25774-02-1

Basic information

• Product Name: PHENYLMALONIC ACID MONOBENZYL ESTER
• Synonyms: PHENYLMALONIC ACID MONOBENZYL ESTER;MONOBENZYL PHENYLMALONATE;phenyl-propanedioicacimono(phenylmethyl)ester;3-(BENZYLOXY)-3-OXO-2-PHENYLPROPANOIC ACID;LABOTEST-BB LT00455270;benzyl hydrogen phenylmalonate;2-Phenylpropanedioic acid hydrogen 1-phenylmethyl ester;mono-Benzyl 2-phenylmalonate
• CAS NO: 25774-02-1
• Molecular Formula: C₁₆H₁₄O₄
• Molecular Weight: 270.28
• EINECS: 247-257-7
• Mol File: 25774-02-1.mol

Chemical Properties

• Melting Point: 64-66°C
• Boiling Point: 432.1°Cat760mmHg
• Flash Point: 160.2°C
• Appearance: /
• Density: 1.258g/cm³
• PKA: 2.97±0.10(Predicted)
• BRN: 1988061
• CAS DataBase Reference: PHENYLMALONIC ACID MONOBENZYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: PHENYLMALONIC ACID MONOBENZYL ESTER(25774-02-1)
• EPA Substance Registry System: PHENYLMALONIC ACID MONOBENZYL ESTER(25774-02-1)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-36
• Hazardous Substances Data: 25774-02-1(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
Phenylmalonic Acid Monobenzyl Ester is used as an intermediate compound for the synthesis of various pharmaceutical products. Its ability to undergo chemical reactions makes it a valuable component in the development of new drugs and medications.
Used in Perfume Industry:
In the perfume industry, Phenylmalonic Acid Monobenzyl Ester is used as a fragrance ingredient. Its chemical properties allow it to contribute to the creation of unique and complex scents in perfumes and other fragranced products.
Used in Plastics Industry:
Phenylmalonic Acid Monobenzyl Ester is used as a component in the production of certain types of plastics. Its versatility in chemical reactions enables it to be incorporated into the manufacturing process, potentially improving the properties of the final plastic products.

Upstream product

• 124-38-9 carbon dioxide 
• 102-16-9 benzyl 2-phenylacetate 

Downstream Products

• 3973-06-6 6β-((Ξ)-2-benzyloxycarbonyl-2-phenyl-acetylamino)-penicillanic acid 
• 59943-21-4 phthlimidomethyl 9-O-(α-benzyloxycarbonyl)phenylacetylclavulanate 
• 62283-14-1 (6S,7S)-7-(2-Benzyloxycarbonyl-2-phenyl-acetylamino)-3-methyl-8-oxo-4-oxa-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzyl ester 
• 35353-13-0 phenyl-2-(benzyloxycarbonyl)acetyl chloride 
• 59943-16-7 benzyl 9-O-(α-benzyloxycarbonyl)phenylacetylclavulanate 
• 406203-78-9 N-(4-carbamimidoyl-phenyl)-2-phenyl-malonamic acid benzyl ester 
• 362467-57-0 N-[4-(2,3-bis-Bocguanidino)benzyl] 2-(benzyl-oxycarbonyl)-2-phenylacetamide 
• 1070671-52-1 benzyl 3-(2-amino-4-(thiophen-2-yl)phenylamino)-3-oxo-2-phenylpropanoate 
• 1059182-79-4 N-(3,4-dimethoxyphenyl)-2-phenyl-N-[2-(4-trifluoromethylphenyl)ethyl]malonamic acid benzyl ester 
• 1111735-72-8 (R,S)-N-(3,4-dimethyl-phenyl)-2-phenyl-N-[2-(4-trifluoromethyl-phenyl)-ethyl]-malonamic acid benzyl ester 
• 1300049-18-6 KNI-10776 

Relevant articles and documents

Lanthanoid Complex as a Novel Carbon Dioxide Carrier for the Carboxylation of Active Methylene Compounds under Mild Conditions

A lanthanoid complex, formed by the addition of a lanthanoid alkoxide to an isocyanate, serves as a novel carbon dioxide carrier for the rapid carboxylation of active methylene compounds under mild conditions.

6α, β-Substituted penicillin derivatives

Novel 6-methoxy and 6-thioalkyl-6-acylamido-penicillanic acids and their non-toxic pharmaceutically-acceptable salts, esters and amides which are useful as antibiotics. The products are prepared by treating an ester of 6-substituted-6-aminopenicillanic acid with an acylating agent followed by removal of the ester group. Also disclosed are novel intermediates.