25784-91-2

Basic information

• Product Name: 2-Chloro-5-nitrobenzoyl chloride
• Synonyms: 2-CHLORO-5-NITROBENZOYL CHLORIDE;2-chloro-5-nitro-benzoylchlorid;Benzoyl chloride, 2-chloro-5-nitro-;2-Chloro-5-Nitrobenzoyl;2-Chloro-5-nitrobenzoic acid chloride
• CAS NO: 25784-91-2
• Molecular Formula: C₇H₃Cl₂NO₃
• Molecular Weight: 220.01
• EINECS: 247-262-4
• Mol File: 25784-91-2.mol

Chemical Properties

• Melting Point: 58-60°C
• Boiling Point: 157-158°C 11mm
• Flash Point: 157-158°C/11mm
• Appearance: /
• Density: 1.575g/cm³
• Vapor Pressure: 0.000705mmHg at 25°C
• Refractive Index: 1.602
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• Sensitive: Moisture Sensitive
• BRN: 2213721
• CAS DataBase Reference: 2-Chloro-5-nitrobenzoyl chloride(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Chloro-5-nitrobenzoyl chloride(25784-91-2)
• EPA Substance Registry System: 2-Chloro-5-nitrobenzoyl chloride(25784-91-2)

Safety Data

• Hazard Codes: C,Xi
• Statements: 34-41
• Safety Statements: 26-36/37/39-45
• RIDADR: 3261
• TSCA: T
• HazardClass: 8
• PackingGroup: II
• Hazardous Substances Data: 25784-91-2(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical and Agrochemical Industries:
2-Chloro-5-nitrobenzoyl chloride is used as a key intermediate for the synthesis of pharmaceuticals and agrochemicals. Its reactivity allows for the creation of a wide range of compounds with potential therapeutic and pesticidal properties.
Used in Organic Synthesis:
As a reagent, 2-Chloro-5-nitrobenzoyl chloride is utilized in organic synthesis, particularly for the preparation of benzoyl chlorides and benzoyl isothiocyanates. These compounds are essential building blocks in the production of various organic molecules.
Used in Dye and Pigment Manufacturing:
2-Chloro-5-nitrobenzoyl chloride is also employed in the manufacturing of dyes, pigments, and other fine chemicals due to its ability to contribute to the color and properties of these products.
Safety Considerations:
Due to its corrosive nature, 2-Chloro-5-nitrobenzoyl chloride should be handled with care to prevent skin, eye, and respiratory system irritation. Proper safety measures and equipment are necessary when working with this compound.

InChI:InChI=1/C7H3Cl2NO3/c8-6-2-1-4(10(12)13)3-5(6)7(9)11/h1-3H

Upstream product

• 2516-96-3 2-chloro-5-nitrobenzoic acid 
• 16588-15-1 2-chloro-5-nitro-benzamide 
• 873-32-5 2-Chlorobenzonitrile 
• 16588-02-6 4-chloro-3-cyanonitrobenzene 
• 95-51-2 o-chloroaniline 
• 118-91-2 ortho-chlorobenzoic acid 
• 79-37-8 oxalyl dichloride 

Downstream Products

• 6307-82-0 2-chloro-5-nitro-benzoic acid methyl ester 
• 130674-22-5 2-chloro-5-nitro-N-(n-propyl)benzamide 
• 109563-06-6 2-chloro-5-nitro-benzoic acid-(2-dimethylamino-ethyl ester); hydrochloride 
• 16588-15-1 2-chloro-5-nitro-benzamide 
• 23082-50-0 2'-chloro-5'-nitroacetophenone 
• 117054-83-8 N-ethyl-2-chloro-5-nitrobenzamide 
• 60587-79-3 N,N-dimethyl-2-chloro-5-nitrobenzamide 
• 22978-25-2 2-chloro-5-nitrobenzanilide 
• 860561-75-7 (2-chloro-5-nitro-benzoyl)-urea 
• 85469-93-8 2-chloro-5-nitro-N-methylbenzamide 
• 34052-37-4 2-chloro-5-nitrobenzophenone 
• 69819-50-7 2-chloro-5-nitro-N-(5-nitro-thiazol-2-yl)-benzamide 
• 54253-05-3 2-chloro-N-(4-chlorophenyl)-5-nitrobenzamide 
• 54252-67-4 5-(2-chloro-5-nitro-benzoyl)-2,3,4,5-tetrahydro-benzo[b][1,4]oxazepine 

Relevant articles and documents

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