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2-[2-hydroxyethyl-(2-methoxyphenyl)amino]ethanol is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 28005-76-7 Structure
  • Basic information

    1. Product Name: 2-[2-hydroxyethyl-(2-methoxyphenyl)amino]ethanol
    2. Synonyms: 2-[2-hydroxyethyl-(2-methoxyphenyl)amino]ethanol
    3. CAS NO:28005-76-7
    4. Molecular Formula: C11H17NO3
    5. Molecular Weight: 211.26
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 28005-76-7.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 350.8°Cat760mmHg
    3. Flash Point: 165.9°C
    4. Appearance: /
    5. Density: 1.177g/cm3
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. PKA: 14.31±0.10(Predicted)
    10. CAS DataBase Reference: 2-[2-hydroxyethyl-(2-methoxyphenyl)amino]ethanol(CAS DataBase Reference)
    11. NIST Chemistry Reference: 2-[2-hydroxyethyl-(2-methoxyphenyl)amino]ethanol(28005-76-7)
    12. EPA Substance Registry System: 2-[2-hydroxyethyl-(2-methoxyphenyl)amino]ethanol(28005-76-7)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 28005-76-7(Hazardous Substances Data)

28005-76-7 Usage

2. Chemical structure

consists of a hydroxyethylamine group and a methoxyphenylamine group attached to an ethanol molecule
3. Common usage: pharmaceutical industry as a precursor in the synthesis of various drugs, particularly those with anti-inflammatory and analgesic properties
4. Applications: formulation of cosmetics and personal care products as a skin-conditioning agent
5. Potential use: in organic chemistry as a reagent for the synthesis of other complex molecules
6. Further research required: to fully understand the properties and potential applications of the compound.

Check Digit Verification of cas no

The CAS Registry Mumber 28005-76-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,8,0,0 and 5 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 28005-76:
(7*2)+(6*8)+(5*0)+(4*0)+(3*5)+(2*7)+(1*6)=97
97 % 10 = 7
So 28005-76-7 is a valid CAS Registry Number.

28005-76-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-[N-(2-hydroxyethyl)-2-methoxyanilino]ethanol

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:28005-76-7 SDS

28005-76-7Relevant articles and documents

A novel optically based chemosensor for the detection of blood Na+

Gunnlaugsson, Thorfinnur,Nieuwenhuyzen, Mark,Richard, Ludovic,Thoss, Vera

, p. 4725 - 4728 (2001)

The azo dye based chemosensor 2 displays extremely good sensitivity and selectivity for Na+ over other physiologically important alkali and alkali earth metal ions in the 0.3-1.0×10-4 M concentration range as well as being pH independent above pH 3.9. This sensitivity coincides with the Na+ concentration range found in blood. The sensor exhibits almost 110 nm hypsochromic shift in the absorption spectrum upon Na+ detection, with a strong colour change from red to yellow in aqueous solution which is clearly visible to the naked eye even at low concentrations.

Chemical and pharmacological characterization of the TRPML calcium channel blockers ML-SI1 and ML-SI3

Leser, Charlotte,Keller, Marco,Gerndt, Susanne,Urban, Nicole,Chen, Cheng-Chang,Schaefer, Michael,Grimm, Christian,Bracher, Franz

, (2020/11/13)

The members of the TRPML subfamily of non-selective cation channels (TRPML1-3) are involved in the regulation of important lysosomal and endosomal functions, and mutations in TRPML1 are associated with the neurodegenerative lysosomal storage disorder muco

Preparation method of Na molecular fluorescent intermediate and preparation method of Na molecular fluorescent sensor

-

Paragraph 0098; 0103-0105, (2019/01/04)

The invention provides a preparation method of a Na molecular fluorescent intermediate and a preparation method of a Na molecular fluorescent sensor. The Na molecular fluorescent intermediatehas a structure as shown in a formula I. The preparation method of the Na molecular fluorescent intermediate comprises the following steps: S1, carrying out a substitution reaction on o-anisidineand alpha-methyl haloacetate to obtain a compound 2; S2, carrying out a reduction reaction on the compound 2 to obtain a compound 3; S3, carrying out a hydroxyl substitution on the compound 4 by adopting toluene sulfonyl chloride to obtain a compound 5, wherein the compound 4 has a structural formula as the follows; S4, carrying out a cyclization reaction on the compound 3 and the compound 5 to obtain a compound 6; S5, carrying out a formylation reaction on the compound 6 to obtain a compound 7; S6, carrying out a henry reaction on the compound 7 with nitromethane to obtain a compound 8; and S7, carrying out nitroso reduction reaction on the compound 8 to obtain the Na molecular fluorescent intermediate. The method is beneficial to improving the yield of the Na molecular fluorescentintermediate.

A fluorescent combinatorial logic gate with Na+, H+-enabled or and H+-driven low-medium-high ternary logic functions

Spiteri, Jasmine M. A.,Mallia, Carl J.,Scerri, Glenn J.,Magri, David C.

supporting information, p. 10116 - 10121 (2017/12/26)

A novel fluorescent molecular logic gate with a 'fluorophore-spacer1-receptor1-spacer2-receptor2' format is demonstrated in 1:1 (v/v) methanol/water. The molecule consists of an anthracene fluorophore, and terti

Sodium-Selective Fluoroionophore-Based Optodes for Seawater Salinity Measurement

Müller, Bernhard J.,Rappitsch, Tanja,Staudinger, Christoph,Rüschitz, Christian,Borisov, Sergey M.,Klimant, Ingo

, p. 7195 - 7202 (2017/07/22)

A new fluorescent sensor for Na+ is presented. The sensor relies on a Na+ selective fluoroionophore based on a bright red-emitting BODIPY chromophore. The fluorescence of the fluoroionophore is enhanced upon binding of Na+-ions to the highly selective aza-crown ether receptor due to reduction of the photoinduced electron transfer (PET) quenching. Solid state sensing materials were prepared by physically embedding the fluoroionophore into water-swellable biocompatible polymer matrices (polyurethane hydrogels), thus enabling continuous measurements of aqueous samples. Despite the simple design, the sensor showed no leaching of the indicator and featured fast and reversible response. Among different polyurethane hydrogels investigated, the hydrogel D1 featuring the highest water uptake was found to be the most suitable due to the highest dynamics between "off" and "on" states. Due to little or no cross sensitivity to other ions (e.g., Mg2+, Ca2+, K+) and its insensitivity to potential changes in pH, this sensor is promising for use in clinical diagnostics and for biological and marine applications. Fiber-optic sensors based on referenced read-out with a compact phase fluorimeter were prepared. To demonstrate their practical applicability, the sensors were used to determine the salinity in the seawater and brackish water of the Baltic Sea.

Synthesis and structure-analgesic activity relationships of a novel series of monospirocyclopiperazinium salts (MSPZ)

Lin, Song-Wen,Sun, Qi,Ge, Ze-Mei,Wang, Xin,Ye, Jia,Li, Run-Tao

supporting information; experimental part, p. 940 - 943 (2011/03/21)

A series of monospirocyclopiperazinium salts were designed and synthesized to search for a peripherally-acting analgesic drug with low side effects. Extensive SAR studies revealed that a suitable NR2R3 was critical for the analgesic activity, which might be beneficial to expose the cationic nitrogen to bind to the receptor, and possibly interact with the receptor via π-π interaction. Introduction of substituting group on the N4-phenyl ring could improve the activity, and the best position was the 4-position. Compound 14n showed more potent analgesic activity (63%, 20 μM/kg, sc) and holds promise for development as a mechanically new analgesic drug.

Detection of mercury in fish organs with a two-photon fluorescent probe

Su Lim, Chang,Won Kang, Dong,Shun Tian, Yu,Hee Han, Ji,Lim Hwang, Hye,Rae Cho, Bong

supporting information; experimental part, p. 2388 - 2390 (2010/08/05)

We report a two-photon fluorescent probe (AHg1) that can be excited by 780 nm femto-second pulses, shows high photostability and negligible toxicity, and can visualize the site of Hg2+ accumulation, but can also estimate trace amounts of mercur

NOVEL PIPERIDINE DERIVATIVE

-

Page/Page column 39, (2008/06/13)

The invention provides a compound of the following formula (1): wherein m, n, and p are independently an integer of 0 - 4, provided 3 ≤ m + n ≤ 8; X is nitrogen atom or a group of the formula: C-R15; Y is a substituted or unsubstituted aromatic group, etc.; R15, R1, R2, R3, R4 , R5, R6 and R7 are hydrogen atom, a substituted or unsubstituted alkyl group, etc.; and Z is hydrogen atom, cyano group, etc., or a prodrug thereof, or a pharmaceutically acceptable salt thereof, which exhibits an action for enhancing LDL receptor expression, and is useful as a medicament for treating hyperlipidemia, atherosclerosis, etc.

A fluorescent chemosensor for sodium based on photoinduced electron transfer

He, Huarui,Mortellaro, Mark A.,Leiner, Marc J. P.,Young, Susanne T.,Fraatz, Robert J.,Tusa, James K.

, p. 549 - 555 (2007/10/03)

A new optical sensor suitable for practical measurement of sodium in serum and whole blood samples is described. The optical sensor is based on a novel PET (photoinduced eletron transfer) fluoroionophore immobilized in a hydrophilic polymer layer. The des

Method of determining an alkali ion

-

, (2008/06/13)

The invention relates to a method of determining an alkali ion in a sample, wherein the alkali ion is contacted with a compound having a luminophoric moiety and an ionophoric moiety, which ionophoric moiety reacts with the alkali ion present in the sample

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