29064-02-6

Upstream product

• 90994-73-3 6-(4-Chloro-benzylamino)-1,3-dimethyl-5-nitro-1H-pyrimidine-2,4-dione 
• 147623-04-9 8-(4-Chloro-phenyl)-1,3-dimethyl-6-phenyl-1,9-dihydro-pyrimido[4,5-b][1,4]diazepine-2,4-dione 
• 13784-07-1 6-amino-5-(4-chloro-benzylideneamino)-1,3-dimethyl-1H-pyrimidine-2,4-dione 
• 42748-11-8 1,2,3,4-Tetrahydro-1,3-dimethyl-6-(4-chlorophenylmethylidenehydrazion)pyrimidin-2,4-dione 
• 58-55-9 theophylline 
• 56075-36-6 1-(4-chlorophenyl)-2-(methylsulfonyl)diazene 
• 104-86-9 4-chlorobenzylamine 
• 122-01-0 4-chloro-benzoyl chloride 
• 5440-00-6 4,5-Diamino-1,3-dimethyluracil 
• 166115-74-8 N-(6-Amino-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydro-pyrimidin-5-yl)-4-chloro-benzamide 
• 147622-95-5 5-Amino-6-[(E)-1-(4-chloro-phenyl)-3-oxo-3-phenyl-propenylamino]-1,3-dimethyl-1H-pyrimidine-2,4-dione 
• 1203-25-4 6-chloro-1,3-dimethyl-5-nitrouracil 

Relevant academic research and scientific papers

Smooth Metal-Free Photoinduced Preparation of Valuable 8-Arylxanthines

A set of 8-arylxanthines was prepared under metal-free conditions and in aqueous solvents from arylazo sulfones and caffeine or theophylline. Notably, the process took place by simply exposing the reaction vessel to visible or solar light, and unreacted xanthine could be easily recovered during the purification step.

Synthesis and in vitro bronchospasmolytic activity of 8-aryl, heteroaryl or arylalkyl theophyllines

Twenty-four 8-aryl- or 8-heteroaryl-substituted theophyllines have been synthesized.The substituents are aromatic rings and heterocycles likely to induce an antiallergic effect or a spasmolytic activity.In vitro evaluation of the bronchospasm caused by ac

REACTIONS OF 5,6-DIAMINO-1,3-DIMETYLURACIL WITH HALOGEN DERIVATIVES OF CHALCONES

The reaction of 5,6-diamino-1,3-dimethyluracil with 1,3-diaryl-2,3-dibromopropan-1-ones gave β-(5-amino-6-imino-1,3-dimethyluracil)chalcones, and conditions for their cyclocondensation to pyrimidinodiazepines were found.For substantiation of the reaction mechanism, the reaction of the diamine with other halogen derivatives of chalcones was studied.The IR, UV, and mass spectra of the synthesized compounds and their condensation products are discussed.

A NEW CONTRACTION OF PTERIDINE 5-OXIDES TO PURINES AND A 7-DEAZAPURINE BY THE 1,3-DIPOLAR CYCLOADDITION REACTION

The 1,3-dipolar cycloaddition reaction of pteridine 5-oxides with dimethyl acetylenedicarboxylate resulted in a new ring contraction of the pyrazine moiety to give purines and a 7-deazapurine.

Reaction of 6-Arylidenehydrazino-1,3-dimethyluracils with Thionyl Chloride Leading to Purine, Thiazolopyrimidine, Pyrimidothiadiazine, Pyrazolopyrimidine, and Thiadiazolopyrimidine Derivatives

The reaction of 6-arylidenehydrazino-1,3-dimethyluracils with thionyl chloride in benzene afforded purine, thiazolopyrimidine, pyrimidothiadiazine, pyrazolopyrimidine, and thiadiazolopyrimidine derivatives, while

Pyrimidine Derivatives and Related Compounds. Part 47. A New Synthesis of Xanthines and Pyrrolopyrimidines by Intramolecular Cyclisation of 6-Substituted 5-Nitrouracil Derivatives

6-Arylalkylamino-1,3-dimethyl-5-nitrouracils (2a-f) were prepared by reaction of 6-chloro-1,3-dimethyl-5-nitrouracil (1) with arylalkylamines in the presence of triethylamine.Among them, the 6-arylalkylaminouracils (2a-d), possessing no substituent at the