309279-56-9Relevant articles and documents
Application of cyclic ketones in MCR: Ugi/amide coupling based synthesis of fused tetrazolo[1,5-a][1,4]benzodiazepines
Yerande, Swapnil G.,Newase, Kiran M.,Singh, Bhawani,Boltjes, André,D?mling, Alexander
supporting information, p. 3263 - 3266 (2014/06/09)
Azido-Ugi reaction involving cyclic ketone, primary amine, isonitrile, and azide afforded substituted tetrazole derivatives 5. These intermediates were hydrolyzed to corresponding acid derivatives. EDAC/HOBt mediated amide bond formation of 5 gave fused tetrazolo[1,5-a][1,4]benzodiazepine 6 in high yield and good diversity.