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N-(3-Chlorophenyl)pivalaMide is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 32597-37-8 Structure
  • Basic information

    1. Product Name: N-(3-Chlorophenyl)pivalaMide
    2. Synonyms: N-(3-Chlorophenyl)pivalaMide;N-(3-Chloro-phenyl)-2,2-dimethyl-propionamide
    3. CAS NO:32597-37-8
    4. Molecular Formula: C11H14ClNO
    5. Molecular Weight: 211.68796
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 32597-37-8.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: N-(3-Chlorophenyl)pivalaMide(CAS DataBase Reference)
    10. NIST Chemistry Reference: N-(3-Chlorophenyl)pivalaMide(32597-37-8)
    11. EPA Substance Registry System: N-(3-Chlorophenyl)pivalaMide(32597-37-8)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 32597-37-8(Hazardous Substances Data)

32597-37-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 32597-37-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,2,5,9 and 7 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 32597-37:
(7*3)+(6*2)+(5*5)+(4*9)+(3*7)+(2*3)+(1*7)=128
128 % 10 = 8
So 32597-37-8 is a valid CAS Registry Number.

32597-37-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name N-(3-Chlorophenyl)-2,2-dimethylpropanamide

1.2 Other means of identification

Product number -
Other names N-(3-chlorophenyl)pivalamide

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:32597-37-8 SDS

32597-37-8Relevant articles and documents

Cyclic sulfone compound and preparation method, application and pharmaceutical composition thereof

-

Paragraph 0121; 0123; 0124; 0125; 0126; 0127, (2021/05/29)

The invention belongs to the technical field of pharmacy, and relates to a cyclic sulfone compound and a preparation method, application and a pharmaceutical composition thereof. The cyclic sulfone compound is shown as a formula (I), is a CXCR2 antagonist

Equivalent Loading of Directed Arenes in Pd(II)-Catalyzed Oxidative Cross-Coupling of Aryl C-H Bonds at Room Temperature

Mei, Chong,Zhao, Mengdi,Lu, Wenjun

, p. 2714 - 2733 (2021/02/01)

The unsymmetrical biaryls (Ar1-Ar2) produced by the catalytic cross-couplings of aryl halides (Ar1-halo) with aryl metallics (Ar2-M) in the loading ratio of 1:1 are popular in chemical synthesis. In contrast, there has been less precedence on the same biaryls produced effectively from two normal aryl C-H bonds with equivalent loading. Here, we report that, in a palladium/oxidant/acid catalytic system at room temperature, one arene (Ar1-H, 1 equiv) can highly selectively couple with the other one (Ar2-H, 1 equiv) to afford the target Ar1-Ar2 just by controlling the directing groups and the substituted groups on their phenyl rings. The utility of this one-one cross-coupling is also demonstrated by synthesis of a few bioactive molecules.

Ligand Promoted Olefination of Anilides for Indirectly Introducing Fluorinated Functional Groups via Palladium Catalyst

Wang, Dongjie,Xu, Xu,Zhang, Jingyu,Zhao, Yingsheng

, p. 2696 - 2705 (2021/02/27)

We report a palladium-catalyzed, ligand promoted, C-H fluorine-containing olefination of anilides with 4-bromo-3,3,4,4-tetrafluorobutene as the fluorinated reagent, which has a potential transformation into other compounds due to its -CF2CF2Br functional group. -CF2CF2H was obtained by using the mild reducing agent sodium borohydride. Bioactive compounds such as aminoglutethimide derivative and propham were well-tolerated in this reaction, both of which highlight the synthetic importance of this method.

Palladium(II)-Catalyzed Oxidative Homo- and Cross-Coupling of Aryl ortho -sp2 C-H Bonds of Anilides at Room Temperature

Mei, Chong,Lu, Wenjun

, p. 4812 - 4823 (2018/04/26)

The preparation of secondary 2,2'-bisanilides has been successfully achieved through an oxidative coupling of aryl ortho-sp2 C-H bonds of anilides in the presence of catalytic Pd(OAc)2 and K2S2O8 as an oxidant in MsOH/CF3CO2H (TFA) at room temperature (25 °C). The aromatic rings of anilides substituted by various electron-donating or electron-withdrawing groups are tolerant in these coupling reactions.

Efficient copper catalysts for C[sbnd]H bond arylation under microwave heating: Direct access to multi-substituted pivanilides

Yang, Hyun Ji,Mathew, Bijoy P.,Oh, Dong Gun,Myung, Kyungjae,Kwak, Ja Hun,Hong, Sung You

, p. 83 - 86 (2016/12/14)

We herein describe a parallel comparison between homogeneous and heterogeneous copper catalysts for microwave-assisted direct C[sbnd]H bond arylation. These catalytic systems feature enhanced catalytic activities, unique bulky ligand/base effects, mild co

Palladium-Catalysed Synthesis of α-(Trifluoromethyl)styrenes by Means of Directed C-H Bond Functionalization

Zhao, Qun,Besset, Tatiana,Poisson, Thomas,Bouillon, Jean-Philippe,Pannecoucke, Xavier

, p. 76 - 82 (2016/01/26)

We report the first introduction of 2-bromo-3,3,3-trifluoropropene (BTP) by directed C-H bond functionalization. The developed method gives straightforward access to α-(trifluoromethyl)styrene derivatives without prior prefunctionalization of the substrates. This palladium-catalysed transformation was applied to a broad range of substrates, and the corresponding trifluoromethylated products were obtained in good yields. This approach represents an alternative pathway to the classical method previously used to access such molecules.

Comparative Catalytic Activity of Group 9 [CpMIII] Complexes: Cobalt-Catalyzed C-H Amidation of Arenes with Dioxazolones as Amidating Reagents

Park, Juhyeon,Chang, Sukbok

supporting information, p. 14103 - 14107 (2016/01/25)

A procedure for the [CpCoIII]-catalyzed direct C-H amidation of arenes with dioxazolone has been developed. This reaction proceeds under straightforward and mild conditions with a broad range of substrates, including anilides. A comparative study on the catalytic activity of Group 9 [{CpMCl2}2] complexes revealed the unique efficiency of the cobalt catalyst. Pick of the bunch: A variety of arenes, including anilides, underwent direct C-H amidation with dioxazolones in the presence of a cobalt catalyst with a Cp? ligand under mild and straightforward reaction conditions (see scheme; Piv=pivaloyl). A comparative study of Group 9 [CpMIII] complexes revealed the unique ability of the cobalt catalyst to promote this transformation efficiently.

A highly efficient Pd-catalyzed decarboxylative ortho-arylation of amides with aryl acylperoxides

Li, Dengke,Xu, Ning,Zhang, Yicheng,Wang, Lei

supporting information, p. 14862 - 14865 (2014/12/11)

An efficient Pd-catalyzed decarboxylative ortho-arylation of amides with aryl acylperoxides was developed. A variety of anilides reacted with aryl acylperoxides to afford the corresponding ortho-arylation products, and N-methoxyarylamides generated phenanthridinones. This journal is

Phosphonated benzoxazole derivatives: Synthesis and metal-complexing properties

Lagadic, Elodie,Bruyneel, Frédéric,Demeyer, Noémie,Hérent, Marie-France,Garcia, Yann,Marchand-Brynaert, Jacqueline

supporting information, p. 817 - 822 (2013/05/22)

Phosphonated benzoxazole derivatives are good candidates as ligands for metal complexes. Two regioisomers were synthesized with the phosphonate function at the C-4 and C-7 positions. Different alkyl chains were also introduced at the C-2 position to functionalize these two regioisomers and increase their complexation properties. The formation of coordination complexes of selected benzoxazoles with M2+ and M3+ metal cations has been screened in solution using HRMS (high-resolution mass spectrometry) as the analytical tool. Georg Thieme Verlag Stuttgart · New York.

Approaches to the synthesis of 2,3-dihaloanilines. Useful precursors of 4-functionalized-1 H-indoles

Guilarte, Veronica,Castroviejo, M. Pilar,Garcia-Garcia, Patricia,Fernandez-Rodriguez, Manuel A.,Sanz, Roberto

experimental part, p. 3416 - 3437 (2011/06/28)

2,3-Dihaloanilines have been proved as useful starting materials for synthesizing 4-halo-1H-indoles. Subsequent or in situ functionalization of the prepared haloindoles allows the access to a wide variety of 2,4- or 2,3,4-regioselectively functionalized indoles in good overall yields. As no efficient synthetic routes to 2,3-dihaloanilines have been described in the literature, different approaches to the preparation of these 1,2,3-functionalized aromatic precursors are now presented. The most general one involves a Smiles rearrangement from the corresponding 2,3-dihalophenols and allows the preparation of 2,3-dihaloanilides in a straightforward and synthetically useful manner.

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