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Tri-tert-butyl N--L-glutamate is a complex organic compound with the molecular formula C31H49NO8. It is a derivative of glutamic acid, an amino acid, and is characterized by the presence of a benzyloxycarbonyl group attached to the γ-glutamyl moiety. tri-tert-butyl N--L-glutamate is often used in peptide synthesis as a protecting group to prevent unwanted side reactions during the formation of peptide bonds. The tert-butyl groups provide additional stability and protection, ensuring that the molecule remains intact during the synthesis process. It is a key intermediate in the preparation of more complex peptide structures, particularly in医药领域, where it can be used to create specific sequences with controlled reactivity.

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  • (s)-di-tert-butyl 2-((s)-4-(((benzyloxy)carbonyl)amino)-5-(tert-butoxy)-5-oxopentanamido)pentanedioate

    Cas No: 32719-56-5

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  • 32719-56-5 Structure
  • Basic information

    1. Product Name: tri-tert-butyl N--L-glutamate
    2. Synonyms: tri-tert-butyl N--L-glutamate
    3. CAS NO:32719-56-5
    4. Molecular Formula:
    5. Molecular Weight: 578.703
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 32719-56-5.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: tri-tert-butyl N--L-glutamate(CAS DataBase Reference)
    10. NIST Chemistry Reference: tri-tert-butyl N--L-glutamate(32719-56-5)
    11. EPA Substance Registry System: tri-tert-butyl N--L-glutamate(32719-56-5)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 32719-56-5(Hazardous Substances Data)

32719-56-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 32719-56-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,2,7,1 and 9 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 32719-56:
(7*3)+(6*2)+(5*7)+(4*1)+(3*9)+(2*5)+(1*6)=115
115 % 10 = 5
So 32719-56-5 is a valid CAS Registry Number.

32719-56-5Downstream Products

32719-56-5Relevant articles and documents

PROCESSES OF PREPARING POLYGLUTAMATED ANTIFOLATES AND USES OF THEIR COMPOSITIONS

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Paragraph 0540; 0541, (2021/02/12)

Provided herein are methods of preparing polyglutamated compounds, such as polyglutamated antifolates, and/or pharmaceutical compositions such as liposomal compositions comprising the same, Also provided herein are substantially pure polyglutamated compou

Quinazoline Antifolates Inhibiting Thymidylate Synthase: Synthesis of Four Oligo(L-γ-glutamyl) Conjugates of N10-Propargyl-5,8-dideazafolic Acid and Their Enzyme Inhibition

Pawelczak, Krzysztof,Jones, Terence R.,Kempny, Michal,Jackman, Ann L.,Newell, David R.,et al.

, p. 160 - 165 (2007/10/02)

The synthesis is described of four oligo(γ-glutamyl) conjugates of N10-propargyl-5,8-dideazafolic acid containing a total of two, three, four, and five L-glutamic acid residues.The tert-butyl group was chosen as the carboxyl protecting group in

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