360-53-2

Basic information

• Product Name: 1-METHOXY-(PERFLUORO-2-METHYL-1-PROPENE)
• Synonyms: methylperfluoroi;1-Methoxy-1,3,3,3-tetrafluoro-2-(trifluoromethyl)prop-1-ene 97%;1-Methoxy-1,3,3,3-tetrafluoro-2-(trifluoromethyl)prop-1-ene, 1,1,1,3-Tetrafluoro-2-(trifluoromethyl)-4-oxapent-2-ene;Methyl 1,3,3,3-tetrafluoro-2-(trifluoromethyl)prop-1-en-1-yl ether 97%;Methyl1,3,3,3-tetrafluoro-2-(trifluoromethyl)prop-1-en-1-ylether97%;1-Propene,1,3,3,3-tetrafluoro-1-methoxy-2-(trifluoromethyl)-;1,3,3,3-tetrafluoro-1-methoxy-2-(trifluoromethyl)-1-propen;ether,methyl1,3,3,3-tetrafluoro-2-(trifluoromethyl)propenyl
• CAS NO: 360-53-2
• Molecular Formula: C₅H₃F₇O
• Molecular Weight: 212.07
• Mol File: 360-53-2.mol

Chemical Properties

• Boiling Point: 98 °C
• Flash Point: 14.6°C
• Appearance: /
• Density: 1.508
• Vapor Pressure: 60.3mmHg at 25°C
• Refractive Index: 1.317
• CAS DataBase Reference: 1-METHOXY-(PERFLUORO-2-METHYL-1-PROPENE)(CAS DataBase Reference)
• NIST Chemistry Reference: 1-METHOXY-(PERFLUORO-2-METHYL-1-PROPENE)(360-53-2)
• EPA Substance Registry System: 1-METHOXY-(PERFLUORO-2-METHYL-1-PROPENE)(360-53-2)

Safety Data

• Hazard Codes: T
• Statements: 23/24/25
• Safety Statements: 26-36-45
• RIDADR: 2810
• HazardClass: TOXIC
• Hazardous Substances Data: 360-53-2(Hazardous Substances Data)

Usage

Uses

Used in Industrial Applications:
1-METHOXY-(PERFLUORO-2-METHYL-1-PROPENE) is used as a solvent or a surfactant due to its unique properties, including chemical inertness, thermal stability, and low surface tension. Its high fluorination content contributes to its performance in these applications.
Used in Chemical Industry:
In the chemical industry, 1-METHOXY-(PERFLUORO-2-METHYL-1-PROPENE) is utilized as a component in the formulation of various products that require its specific characteristics, such as resistance to combustion and low friction.
Used in Research and Development:
1-METHOXY-(PERFLUORO-2-METHYL-1-PROPENE) is employed in research and development for the creation of new materials and compounds that can benefit from its unique properties, such as its chemical inertness and thermal stability.
It is important to handle 1-METHOXY-(PERFLUORO-2-METHYL-1-PROPENE) with care and follow safety guidelines to mitigate potential health and environmental risks associated with its highly fluorinated nature.

InChI:InChI=1/C5H3F7O/c1-13-3(6)2(4(7,8)9)5(10,11)12/h1H3

Upstream product

• 67-56-1 methanol 
• 382-21-8 perfluoroisobutylene 
• 382-26-3 1,1,1,3,3-pentafluoro-3-methoxy-2-trifluoromethylpropane 
• 1067-52-3 tributyltin methoxide 
• 56152-71-7 1-chloro-2-trifluoromethyl-1,3,3,3-tetrafluoro-1-propene 

Downstream Products

• 1735-87-1 3,3,3-Trifluoro-2-methyl-2-(trifluoromethyl)propanoyl fluoride 
• 382-26-3 1,1,1,3,3-pentafluoro-3-methoxy-2-trifluoromethylpropane 
• 97653-57-1 2-methyl-4-fluoro-5-trifluoromethyl-6-methoxypyrimidine 
• 92983-83-0 2-phenyl-4-fluoro-5-trifluoromethyl-6-methoxypyrimidine 
• 593-53-3 Methyl fluoride 
• 684-36-6 perfluoromethacryloyl fluoride 
• 684-22-0 bis(trifluoromethyl)ketene 
• 382-30-9 1,1,1,3,3,3-Hexafluoro-2-methoxymethyl-propane 
• 163702-08-7 nonafluoroisobutyl methyl ether 
• 97653-67-3 4,6-Dimethoxy-2-phenyl-5-trifluoromethyl-pyrimidine 
• 163702-07-6 methyl nonafluorobutyl ether 
• 564-10-3 3,3,3-trifluoro-2-(trifluoromethyl)propanoic acid 
• 360-54-3 methyl 2-(trifluoromethyl)-3,3,3-trifluoropropionate 

Relevant articles and documents

Synthesis of 1-aroyl(1-arylsulfonyl)-4-bis(trifluoromethyl)alkyl semicarbazides as potential physiologically active compounds

1,1-Bis(trifluoromethyl)alkyl isocyanates obtained from perfluoroisobutene (PFIB) react with aroyl(arylsulfonyl)hydrazines. Twenty eight prospective biologically active polyfluorinated 1,4-substituted semicarbazides were synthesized. The structure of each

Synthesis and anticancer activity of N-bis(trifluoromethyl)alkyl-N′-thiazolyl and N-bis(trifluoromethyl)alkyl-N′-benzothiazolyl ureas

A number of N-bis(trifluoromethyl)alkyl-N′-thiazolyl and -benzothiazolyl ureas have been synthesized and evaluated for their in vitro antiproliferative activities against the human cancer cell lines at the National Cancer Institute (NCI, USA). The activity was shown for compounds 8a,c and 9a-c. The most sensitive cell lines relative to the tested compounds are: 8c PC-3 (prostate cancer, log GI50 -7.10), 9c SNB-75 (CNS cancer, log GI50 -5.84), 9b UO-31 (renal cancer, log GI50 -5.66), and SR (leukemia, log GI50 -5.44) human cancer cells.

Iridium-catalyzed reactions of trifluoromethylated compounds with alkenes: A Csp3-H bond activation α to the trifluoromethyl group

(Chemical Equation Presented) Catalytic convenience: The use of iridium or ruthenium catalysts for Csp3-H bond activation has led to the addition reaction of trifluoromethylated compounds to alkenes (see scheme). This atom-economical reaction o

Exchange reactions of organotin and organosilicon compounds with vinylic fluorine

Compounds carrying reactive fluorine atoms, such as methylphosphonis difluoride and perfluoroisobutene, undergo facile exchange with organosilanes and stannanes.Reactions with protic nucleophiles also yield similar products.To account for the products formed and observed reactivity differences, appropriate mechanisms are proposed.The reactions described herein have considerable synthetic utility.

CONVERSION OF METHOXYPERFLUOROISOBUTENE TO α-METHYLHEXAFLUOROISOBUTYRIC ACID FLUORIDE BY A PHASE TRANSFER CATALYST

Methoxyperfluoroisobutene was converted to α-methylhexafluoroisobutyric acid fluoride by a catalytic amount of phase transfer catalyst in quantitative yield.