1-Propene, 1,3,3,3-tetrafluoro-1-methoxy-2-(trifluoromethyl)-

Base Information

• Chemical Name: 1-Propene, 1,3,3,3-tetrafluoro-1-methoxy-2-(trifluoromethyl)-
• CAS No.: 360-53-2
• Molecular Formula: C5H3 F7 O
• Molecular Weight: 212.067
• Hs Code.: 2909199090
• European Community (EC) Number: 671-732-1
• DSSTox Substance ID: DTXSID5073167
• Nikkaji Number: J27.132B
• Mol file: 360-53-2.mol

Synonyms:360-53-2;1,3,3,3-tetrafluoro-1-methoxy-2-(trifluoromethyl)prop-1-ene;1-Propene, 1,3,3,3-tetrafluoro-1-methoxy-2-(trifluoromethyl)-;1,1,1,3-tetrafluoro-2-(trifluoromethyl)-4-oxapent-2-ene;Methyl perfluoroisobutenyl ether;Heptafluoroisobutylene methyl ether;ETHER, METHYL HEPTAFLUOROISOBUTENYL;1-Methoxy-(perfluoro-2-methyl-1-propene);BRN 1787514;1-methoxy(perfluoro-2-methyl-1-propene);Ether, methyl 1,3,3,3-tetrafluoro-2-(trifluoromethyl)propenyl;Ether, methyl tetrafluoro-2-(trifluoromethyl)propenyl;1,3,3,3-Tetrafluoro-1-methoxy-2-(trifluoromethyl)-1-propene;SCHEMBL154401;DTXSID5073167;1-methoxyheptafluoro-1-isobutene;heptafluoroisobutenyl methyl ether;MFCD00054679;AKOS015852384;LS-67865;FT-0607997;A823103;1,3,3,3-Tetrafluoro-2-trifluoromethyl-1-methoxy-1-propene;1-methoxy-1,3,3,3-tetrafluoro-2-(trifluoromethyl)prop-1-ene;1-Propene, 1-methoxy-2-trifluoromethyl-1,3,3,3-tetrafluoro-;1,3,3,3-Tetrafluoro-1-methoxy-2-(trifluoromethyl)-1-propene #

Chemical Property of 1-Propene, 1,3,3,3-tetrafluoro-1-methoxy-2-(trifluoromethyl)-

Chemical Property:

• Vapor Pressure: 60.3mmHg at 25°C
• Refractive Index: 1.317
• Boiling Point: 91.7°Cat760mmHg
• Flash Point: 14.6°C
• PSA: 9.23000
• Density: 1.424g/cm³
• LogP: 2.93850
• XLogP3: 3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 1
• Exact Mass: 212.00721185
• Heavy Atom Count: 13
• Complexity: 194

Purity/Quality:

99% ^*data from raw suppliers

1,1,1,3-Tetrafluoro-2-(trifluoromethyl)-4-oxapent-2-ene 97% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: T
• Statements: 23/24/25
• Safety Statements: 26-36-45

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC(=C(C(F)(F)F)C(F)(F)F)F

Technology Process of 1-Propene, 1,3,3,3-tetrafluoro-1-methoxy-2-(trifluoromethyl)-

There total 7 articles about 1-Propene, 1,3,3,3-tetrafluoro-1-methoxy-2-(trifluoromethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.7%

1,1,1,3,3-pentafluoro-3-methoxy-2-trifluoromethylpropane (382-26-3) → 1,3,3,3-tetrafluoro-1-methoxy-2-trifluoromethyl-propene (360-53-2) + 1,1,3,3-Tetrafluoro-3-methoxy-2-trifluoromethyl-propene

Guidance literature:

With potassium hydroxide; at 65 - 80 ℃; for 1.5h; var. reag.: NaOH, Ca(OH)2;

DOI:10.1016/S0022-1139(00)85113-1

Reference yield: 72.0%

1,1,1,3,3-pentafluoro-3-methoxy-2-trifluoromethylpropane (382-26-3) → 1,3,3,3-tetrafluoro-1-methoxy-2-trifluoromethyl-propene (360-53-2)

Guidance literature:

With calcium hydroxide; N-benzyl-N,N,N-triethylammonium chloride; In water;

DOI:10.1016/S0022-1139(00)84991-X

Reference yield: 69.0%

methanol (67-56-1) + perfluoroisobutylene (382-21-8) → 1,3,3,3-tetrafluoro-1-methoxy-2-trifluoromethyl-propene (360-53-2)

Guidance literature:

methanol; perfluoroisobutylene; at 20 ℃; for 48h; Autoclave;

With potassium hydroxide; In diethyl ether;

DOI:10.1016/j.ejmech.2009.08.007

upstream raw materials:

methanol

perfluoroisobutylene

1,1,1,3,3-pentafluoro-3-methoxy-2-trifluoromethylpropane

tributyltin methoxide

Downstream raw materials:

3,3,3-Trifluoro-2-methyl-2-(trifluoromethyl)propanoyl fluoride

nonafluoroisobutyl methyl ether

3,3,3-trifluoro-2-(trifluoromethyl)propanoic acid

methyl nonafluorobutyl ether

Refernces

• 1、 Koshar et al.. "-". . p. 1741,1742. Retrieved 1957.
• 2、 Guo, Yong,Zhao, Xiaming,Zhang, Dazhi,Murahashi, Shun-Ichi. "Iridium-catalyzed reactions of trifluoromethylated compounds with alkenes: A Csp3-H bond activation α to the trifluoromethyl group". supporting information; experimental part. p. 2047 - 2049. Retrieved 2009/07/25.
• 3、 Rossman, D. I.,Muller, A. J.. "Exchange reactions of organotin and organosilicon compounds with vinylic fluorine". . p. 61 - 68. Retrieved 2007/10/02.