3673-68-5

Basic information

• Product Name: 2-(3,5-di-t-butyl-4-hydroxyphenyl)ethanol
• Synonyms: 2-(3,5-di-t-butyl-4-hydroxyphenyl)ethanol
• CAS NO: 3673-68-5
• Molecular Weight: 250.381
• Mol File: 3673-68-5.mol

Chemical Properties

• CAS DataBase Reference: 2-(3,5-di-t-butyl-4-hydroxyphenyl)ethanol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3,5-di-t-butyl-4-hydroxyphenyl)ethanol(3673-68-5)
• EPA Substance Registry System: 2-(3,5-di-t-butyl-4-hydroxyphenyl)ethanol(3673-68-5)

Safety Data

• Hazardous Substances Data: 3673-68-5(Hazardous Substances Data)

Upstream product

• 4130-42-1 2,6-di-tert-butyl-4-ethylphenol 
• 75-21-8 oxirane 
• 128-39-2 2,6-di-tert-butylphenol 
• 98-82-8 Isopropylbenzene 
• 80-15-9 Cumene hydroperoxide 
• 40056-42-6 3,5-di-tert-butyl-4-hydroxyphenylacetyl chloride 
• 107-21-1 ethylene glycol 
• 112-27-6 2,2'-[1,2-ethanediylbis(oxy)]bisethanol 
• 507-19-7 t-butyl bromide 
• 501-94-0 p-hydroxyphenethyl alcohol 
• 1611-03-6 3,5-di-tert-butyl-4-hydroxyphenyl acetic acid 

Downstream Products

• 7019-93-4 2,6-di-tert-butyl-4-(2-hydroxyethylidene)cyclohexa-2,5-dien-1-one 
• 125489-21-6 1-(3,5-di-tert-butyl-4-hydroxyphenyl)-1,2-ethanediol 
• 28145-35-9 4-(2-chloroethyl)phenol 
• 14140-15-9 4-(2-bromoethyl)phenol 
• 1131688-06-6 C₁₉H₃₀O₂ 
• 106-44-5 p-cresol 
• 13196-10-6 benzofuran-5-ol 
• 123-07-9 4-Ethylphenol 
• 501-94-0 p-hydroxyphenethyl alcohol 
• 1240059-73-7 1-[4-(2-hydroxyethyl)phenoxy]-2-(4'-hydroxyphenyl)ethane 
• 501123-58-6 di[2-(4-hydroxyphenyl)]ethyl ether 
• 117516-54-8 6-tert-butyl-5-hydroxybenzofuran 
• 108-95-2 phenol 
• 176308-57-9 2-(tert-butyl)-4-(2-hydroxyethyl)phenol 

Relevant articles and documents

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The use of biophenols to synthesize antioxidants has greatly developed due to their capability of solving environmental problems, economical reasons and renewability. In the present work, the tyrosol derived from olive mill wastewater (OMWW) was alkylated

β-Hydroxyalkylation of sterically hindered phenols with epoxides in acid medium

Reactions of 2,6-dialkylphenols with ethylene oxide, propylene oxide and epichlorohydrin in the presence of SnCl4 at the temperature from -5 to +5°C leads to the formation of respective phenols containing a hydroxy group in the β-position of the aliphatic chain of the para-substituent. The conditions for maximum selectivity of the reaction of 2,6-di-tert-butylphenol with ethylene oxide were determined. By HPLC-MS method the directions of the side reactions were explored. The method has been successfully tested in a pilot installation. With 2,6-dimethylphenol instead of 2,6-di-tert-butylphenol a sharp increase occurs in the content of ethers in the reaction product. With epichlorohydrin, 2,6-di-tert-butylphenol affords a product, which is easily converted into an epoxide containing a sterically hindered phenol in its structure.

Development of a one-stage synthesis of 2,6-di-tert-4-ethylbutylphenol from 2,6-di-tert-butylphenol

Investigation of the catalyzed reaction of 2,6-di-tert-butylphenol with ethanol, ethylene glycol, oligomeric glycols, and paraldehyde in a strongly basic medium permitted to develop a technologically suitable procedure for manufacture of 2,6-di-tert-4-ethyl-butylphenol, used in the synthesis of Antioxidant-425.

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Novel substituted phosphazene compounds are disclosed having the formula STR1 wherein w, x, y and z are integers the sum of which is from 3 to 6 with the proviso that w is at least 1 but equal to or less than (w+x+y+z)-1, x is from 1 to 5, y and z are from 0 to 2; R1 and R2 are the same or different and are C1 to C6 linear or branched alkyl; R3 is an unsubstituted or substituted aryl and n is 0 or an integer from 2 to 6; Q is --O--, STR2 --NR-- or --S--; Ar is STR3 R' and R are the same or different and are C1 to C6 linear or branched alkyl, with the proviso that R can also be hydrogen, wherein R1 and R2 are the same or different C1 to C4 linear or branched alkyl group and n is 0 or an integer from 2 to 6. These compounds display good solubilities in both organic and aqueous systems. Accordingly, they act as antioxidants in adhesive, sealant and coating compositions.