374796-29-9Relevant articles and documents
CYCLOPROPYLAMINE COMPOUND AS LSD1 INHIBITOR AND USE THEREOF
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Paragraph 0179-0180; 0184, (2021/07/24)
Provided is a cyclopropylamine compound as lysine-specific demethylase 1 (LSD1) inhibitor, and a use thereof in preparation of drug for treating diseases associated with LSD1. The cyclopropylamine compound is a compound represented by formula (I), an isomer thereof, and a pharmaceutically acceptable salt thereof.
Nitroimidazole compound as well as preparation method and application thereof
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, (2021/02/10)
The invention discloses a novel nitroimidazole compound as well as a preparation method and application thereof. The nitroimidazole compound has a general formula (I) shown in the specification.
Spirocyclic amino alcohol building blocks prepared via a Prins-type cyclization in aqueous sulfuric acid
Lukin, Alexey,Bagnyukova, Darya,Kalinchenkova, Natalya,Zhurilo, Nikolay,Krasavin, Mikhail
supporting information, p. 3311 - 3314 (2016/07/11)
A convenient Prins cyclization of various azacycloalkanones with homoallylic alcohol was achieved in aqueous sulfuric acid. The formal four-center, three-component reaction provides a facile and flexible entry into a range of spirocyclic amino alcohols wh
Cyclohexane derivatives and their use as therapeutic agents
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Page 36, (2010/02/06)
The present invention relates compounds of formula (I), wherein ring A is a phenyl or pyridyl ring; X represents a linker selected from the group consisting of formulae: (a), (b), (c), (d), and (e); and R1, R2, R3, R4, R5, R6, R7, R13, R14, R15, R16, R17, R21a and R21b are as defined herein. The compounds are of particular use in the treatment or prevention of depression, anxiety, pain, inflammation, migraine, emesis or postherpetic neuralgia.