3874-31-5

Basic information

• Product Name: 1-(2,5-DIFLUOROPHENYL)ETHANOL
• Synonyms: 1-(2,5-DIFLUOROPHENYL)ETHANOL
• CAS NO: 3874-31-5
• Molecular Formula: C₈H₈F₂O
• Molecular Weight: 158.15
• Mol File: 3874-31-5.mol

Chemical Properties

• Appearance: /
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 1-(2,5-DIFLUOROPHENYL)ETHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2,5-DIFLUOROPHENYL)ETHANOL(3874-31-5)
• EPA Substance Registry System: 1-(2,5-DIFLUOROPHENYL)ETHANOL(3874-31-5)

Safety Data

• Hazardous Substances Data: 3874-31-5(Hazardous Substances Data)

Usage

Type of compound

Organic compound

Structure

Phenyl ring with two fluorine atoms and an attached ethanol group

Usage

Building block in organic synthesis

Role

Starting material for the production of various compounds

Function

Reagent in chemical reactions, particularly in the formation of new carbon-carbon and carbon-heteroatom bonds

Applications

Pharmaceutical, agricultural, and material science industries

Potential

Development of new drugs, agrochemicals, and advanced materials

Upstream product

• 446-29-7 1-(4-fluoro-2-methylphenyl)ethanone 
• 2646-90-4 2,5-difluorobenzaldehyde 
• 75-16-1 methylmagnesium bromide 
• 540-36-3 para-difluorobenzene 
• 75-07-0 acetaldehyde 
• 1979-36-8 2',5'-difluoroacetophenone 

Downstream Products

• 398-70-9 2,5-difluorostyrene 
• 1080636-32-3 C₁₀H₈F₂O 
• 1346817-88-6 3-(1-(2,5-difluorophenyl)ethoxy)-2-nitropyridine 
• 1346818-05-0 3-(1-(2,5-difluorophenyl)ethoxy)pyridin-2-amine 
• 1346818-36-7 5-bromo-3-(1-(2,5-difluorophenyl)ethoxy)pyridin-2-amine 
• 1613148-56-3 5-bromo-N,N-bis(tert-butoxycarbonyl)-3-(1-(2,5-difluorophenyl)ethoxy)pyridin-2-amine 
• 1613148-57-4 N,N-bis(tert-butoxycarbonyl)-3-(1-(2,5-difluorophenyl)ethoxy)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine 
• 1613148-58-5 N,N-bis(tert-butoxycarbonyl)-5-(5-(tert-butoxycarbonyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl)-3-(1-(2,5-difluorophenyl)ethoxy)pyridin-2-amine 
• 1613148-55-2 3-(1-(2,5-difluorophenyl)ethoxy)-5-(4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl)pyridin-2-amine 
• 1613148-60-9 3-(6-(bis(tert-butoxycarbonyl)amino)-5-(1-(2,5-difluorophenyl)ethoxy)pyridin-3-yl)-6-(tert-butoxycarbonyl)-5,6,7,8-tetrahydro-1,6-naphthyridin-8-ol 
• 1613148-59-6 3-(6-amino-5-(1-(2,5-difluorophenyl)ethoxy)pyridin-3-yl)-5,6,7,8-tetrahydro-1,6-naphthyridin-8-ol 
• 126534-37-0 (R)-1-(2,5-difluorophenyl)ethanol 

Relevant articles and documents

Substituted pyridine compound and its method and use thereof

The invention relates to a novel substitutive pyridine compound, and a pharmaceutically acceptable salt and a pharmaceutical preparation of the substitutive pyridine compound for regulating the activity of protein kinases and regulating signal responses between cells or in the cells. Meanwhile, the invention further relates to a pharmaceutical composition containing the compound provided by the invention, and a method for treating high proliferative diseases of mammals, especially human with the pharmaceutical composition.

SALT OF HALOGEN-SUBSTITUTED HETEROCYCLIC COMPOUND

The invention provides a novel α-halogen-substituted thiophene compound salt that has a potent LPA receptor antagonistic action and is useful as a medicament. The salt is represented by the general formula (I): (wherein R is a hydrogen atom or a methoxy g

Substituted ring compound and its method and use thereof

The invention provides a substituted cyclic compound as well as a use method and application thereof. The compound is a compound as shown in a formula (I) or stereoisomers, stereomers, tautomers, nitric oxides, solvates, metabolites and pharmaceutically acceptable salts or prodrugs of the compound as shown in the formula (I). The invention further provides a medicament composition containing the compound. The compound and the medicament composition are capable of regulating the activity of protein kinase in a biological sample body and are used for protecting, treating or relieving proliferative diseases of patients. The formula (I) is as shown in the specification.

SUBSTITUTED CYCLIC COMPOUNDS AND METHODS OF USE

The present invention provides novel substituted alkynyl compounds, pharmaceutical acceptable salts and formulations thereof useful in modulating the protein tyrosine kinase activity, and in modulating cellular activities such as proliferation, differentiation, apoptosis, migration and invasion. The invention also provides pharmaceutically acceptable compositions comprising such compounds and methods of using the compositions in the treatment of hyperproliferative disorders in mammals, especially humans.

ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS

Described herein are compounds that are antagonists of lysophosphatidic receptor(s). Also described are pharmaceutical compositions and medicaments that include the compounds described herein, as well as methods of using such antagonists, alone and in combination with other compounds, for treating LPA-dependent or LPA-mediated conditions or diseases.

SUBSTITUTED HETEROCYCLIC DERIVATIVES AND THEIR PHARMACEUTICAL USE AND COMPOSITIONS

Compounds of the general Formula I, wherein X1, X2, X3, X4, X5, X6, X7, R1, R2, R4, R5, R6, R7, R8, R9, R10, Y1, n, m, p and q are defined as above, their preparation and their use as antimicrobial agents.