408523-59-1

Basic information

• Product Name: 2,4-DICHLORO-6-NITROQUINOLINE
• Synonyms: 2,4-DICHLORO-6-NITROQUINOLINE
• CAS NO: 408523-59-1
• Molecular Formula: C9H4Cl2N2O2
• Molecular Weight: 243.05
• Mol File: 408523-59-1.mol

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 2,4-DICHLORO-6-NITROQUINOLINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-DICHLORO-6-NITROQUINOLINE(408523-59-1)
• EPA Substance Registry System: 2,4-DICHLORO-6-NITROQUINOLINE(408523-59-1)

Safety Data

• Hazardous Substances Data: 408523-59-1(Hazardous Substances Data)

Usage

Uses

Used in Agricultural Industry:
2,4-Dichloro-6-nitroquinoline is used as a crop protectant for its antifungal and antimicrobial properties, which help in safeguarding crops from various pathogens and pests, thereby ensuring a healthy and productive yield.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 2,4-dichloro-6-nitroquinoline is used as a research compound for its potential antibacterial and antitumor activities. Its ability to target and inhibit the growth of bacteria and tumor cells makes it a promising candidate for the development of new drugs and therapies.
It is crucial to handle 2,4-dichloro-6-nitroquinoline with care, as it may pose health risks if ingested, inhaled, or if it comes into contact with the skin or eyes, causing irritation. Proper safety measures should be taken during its use to minimize any potential hazards.

Upstream product

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• 863723-28-8 6-nitro-1H-quinoline-2,4-dione 
• 125600-42-2 2-amino-5-nitrophenylacetylene 
• 503-38-8 trichloromethyl chloroformate 
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• 6293-83-0 2-iodo-4-nitrophenylamine 
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• 10390-08-6 ethyl 3-((4-nitrophenyl)amino)-3-oxopropanoate 
• 100-01-6 4-nitro-aniline 
• 264260-06-2 6-nitro-quinoline-2,4-diol 

Downstream Products

• 437708-76-4 4-chloro-6-nitro-2-piperazin-1-yl-quinoline 

Relevant articles and documents

Acetonitrile-mediated synthesis of 2,4-dichloroquinoline from 2-ethynylaniline and 2,4-dichloroquinazoline from anthranilonitrile

2,4-Dichloroquinolines and 2,4-dichloroquinazolines were synthesized from 2-ethynylanilines and anthranilonitriles, respectively, using diphosgene in acetonitrile and heating at 130 °C or 150 °C for 12 hours. This reaction was applied to the synthesis of 4,6-dichloropyrazolo[3,4-d]pyrimidine (dichloro-9H-isopurine). The postulated mechanism is also described. Georg Thieme Verlag Stuttgart.

QUINOLINE TACHYKININ RECEPTOR ANTAGONISTS

The present invention is directed to certain quinoline compounds which are useful as neurokinin-1 (NK-1) receptor antagonists, and inhibitors of tachykinin and in particular substance P. The invention is also concerned with pharmaceutical formulations comprising these compounds as active ingredients and the use of the compounds and their formulations in the treatment of certain disorders, including emesis, urinary incontinence, depression, and anxiety.

Syntheses and binding affinities of 6-nitroquipazine analogues for serotonin transporter. Part 4: 3-Alkyl-4-halo-6-nitroquipazines

On the basis of the structure-activity relationship (SAR) of 4-chloro-6-nitroquipazine (Ki = 0.03 nM) and 3-fluoropropyl-6- nitroquipazine (Ki = 0.32 nM), 3-alkyl-4-halo-6-nitroquipazines were synthesized and tested for their potenti

Syntheses and binding affinities of 6-nitroquipazine analogues for serotonin transporter. Part 2: 4-Substituted 6-nitroquipazines

Eleven 4-substituted derivatives of 6-nitroquipazine were synthesized and evaluated for their abilities to displace [3H]citalopram binding to the rat cortical synaptic membranes. Among them, 4-chloro-6-nitroquipazine was shown to possess the hi