41207-34-5

Basic information

• Product Name: (E)-2-OCTADECENOL
• Synonyms: 2-Octadecenol;(E)-2-OCTADECENOL;trans-2-octadecen-1-ol
• CAS NO: 41207-34-5
• Molecular Formula: C₁₈H₃₆O
• Molecular Weight: 268.4778
• Mol File: 41207-34-5.mol

Chemical Properties

• Boiling Point: 351.1 °C at 760 mmHg
• Flash Point: 154.6 °C
• Appearance: /
• Density: 0.847 g/cm³
• CAS DataBase Reference: (E)-2-OCTADECENOL(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-2-OCTADECENOL(41207-34-5)
• EPA Substance Registry System: (E)-2-OCTADECENOL(41207-34-5)

Safety Data

• Hazardous Substances Data: 41207-34-5(Hazardous Substances Data)

Usage

Uses

Used in Food Industry:
(E)-2-Octadecenol is used as a flavoring agent for imparting its distinctive sweet, floral, and waxy notes to food products, enhancing their overall sensory appeal and consumer experience.
Used in Cosmetic Industry:
In the cosmetic sector, (E)-2-Octadecenol serves as a fragrance component, adding a pleasant and natural scent to various cosmetic products, thereby increasing their marketability and consumer acceptance.
Used in Pharmaceutical Industry:
(E)-2-Octadecenol finds potential applications in the pharmaceutical field, where it may be utilized for its properties or as a component in the development of new medicinal formulations.
Used as a Chemical Intermediate:
(E)-2-Octadecenol also functions as an intermediate in the synthesis of other chemicals, contributing to the production of a range of chemical products that serve diverse industrial needs.

Upstream product

• 150989-02-9 octadec-2t-enoyl chloride 
• 2833-97-8 octadec-2-yn-1-ol 
• 94874-12-1 ethyl trans-octadec-2-enoate 
• 2825-79-8 (E)-2-octadecenoic acid 
• 65144-03-8 ethyl 3-hydroxyoctadecanoate 
• 36653-82-4 1-Hexadecanol 
• 14663-11-7 methyl trans-2-octadecenoate 
• 867-13-0 diethoxyphosphoryl-acetic acid ethyl ester 
• 629-80-1 n-hexadecylaldehyde 
• 88303-25-7 tetradecylmagnesium bromide 
• 26186-00-5 1-heptadecyne 
• 629-72-1 pentadecyl bromide 
• 7390-81-0 2-hexadecyloxirane 
• 4111-54-0 lithium diisopropyl amide 

Downstream Products

• 51534-37-3 (E)-octadec-2-enal 
• 1164104-56-6 (R,E)-1-(tert-butyldiphenylsilyloxy)-3-(octadec-2-en-1-yloxy)propan-2-ol 
• 1164104-62-4 (R,E)-3-(tert-butyldiphenylsilyloxy)-2-(octadec-2-en-1-yloxy)propan-1-ol 
• 1354747-56-0 C₄₃H₇₄FNO₇ 
• 1354747-53-7 C₇₃H₁₁₉NO₇ 
• 1354747-52-6 C₄₈H₆₇NO₇ 
• 1354747-51-5 C₅₆H₇₅NO₉ 
• 1354747-50-4 C₄₈H₆₉NO₈ 
• 1354747-49-1 C₅₅H₇₃NO₉ 
• 1354747-48-0 C₅₄H₇₂O₈ 
• 1354747-47-9 C₂₅H₄₀O₂ 
• 1306772-68-8 (R,R)-1-(N,N-dibenzylamino)-2,3-epoxyoctadecane 

Relevant articles and documents

Ligand-controlled cobalt-catalyzed remote hydroboration and alkene isomerization of allylic siloxanes

The Co-catalyzed remote hydroboration and alkene isomerization of allylic siloxanes were realized by a ligand-controlled strategy. The remote hydroboration with dcype provided borylethers, while xantphos favored the formation of silyl enol ethers.

Synthesis of C -glycoside analogues of α-galactosylceramide via linear allylic C-H oxidation and allyl cyanate to isocyanate rearrangement

C-Glycoside analogues of α-galactosylceramide were synthesized in which several significant modifications known to promote Th-1 cytokine production were included. The key transformations include C-H oxidation, Sharpless asymmetric epoxidation, olefin cros

Ring-opening hydrofluorination of 2,3- and 3,4-epoxy amines by HBF 4·OEt2: Application to the asymmetric synthesis of (S, S)-3-deoxy-3-fluorosafingol

Treatment of a range of 2,3- and 3,4-epoxy amines with HBF 4·OEt2 at room temperature results in fast and efficient SN2-type ring-opening hydrofluorination to give stereodefined amino fluorohydrins. Operational simplicity, scalability, and short reaction time at ambient temperature are notable features of this method. The utility of this methodology is exemplified in a concise asymmetric synthesis of (S,S)-3-deoxy-3-fluorosafingol.

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Starting from palmityl alcohol, divergent stereoselective syntheses of spisulosine and its diastereo- and regio-isomers have been achieved. In the Sharpless asymmetric dihydroxylation-based approach, the key step is the synthesis of monoprotected diol, whereas Miyashita's boron-directed C-2 regioselective azidolysis of enantiomerically pure epoxy alcohol is the vital step in the Sharpless asymmetric epoxidation-based route. The latter approach involves the first protecting-group-free synthesis of spisulosine.

An improved two-step synthetic route to primary allylic alcohols from aldehydes

An improved two-step synthetic route to allylic alcohols from aldehydes has been developed. A modification of the HWE reaction in H2O-2-PrOH (1 : 1) and a convenient protocol to prepare AlH3 in THF from LiAlH 4 and n-BuBr are the key factors in the improvement.

Synthesis and antioxidant properties of an unnatural plasmalogen analogue bearing a trans O-vinyl ether linkage

To assess the antioxidant behavior of trans-1, we first synthesized trans-allyl ether 4 by opening an (S)-glycildol derivative with an (E)-alk-2en-ol, and then produced the unnatural E-enol ether 1 by a stereoselective iridium(I)-catalyzed olefin isomerization. Natural cis-1 was preferentially degraded by HOCI and was more protective than trans-1 against lipid peroxidation Induced by a free-radical Initiator, demonstrating that the geometry of the 1-alkenyloxy bond participates In the antioxidant defensive role of 1.

A stereoselective synthesis of dihydrosphingosine

A highly enantioselective synthesis of D-(+)-erythro-dihydrosphingosine (sphinganine) as its triacetate derivative 10, starting from palmityl alcohol (3) and employing the Sharpless asymmetric dihydroxylation as the key step, is described.

Pheromone synthesis, CLXXV: Synthesis of koiganal I and II, the sex pheromone components of the webbing clothes moth

Koiganal I [(E)-2-octadecenal (1)] and II [(2E,13Z)-2,13-octadecadienal (2)], the female-produced pheromone components of the webbing clothes moth (Tineola bisselliella), were synthesized. VCH Verlagsgesellschaft mbH, 1997.

Selective Isomerization of 1,2-Epoxyalkanes to Aldehydes with Lithium Dialkylamides

Reaction of a variety of 1,2-epoxyalkanes with 2.5 equiv. of bulky metal amide - lithium 2,2,6,6-tetramethylpiperidide - affords the corresponding aldehydes exclusively in high yields; this is the first example of base-promoted isomerization of monosubstituted epoxides to aldehydes.

Synthesis of Sphingosine Relatives, XIV. A New Synthesis of Symbioramide, a Ca(++)-ATPase Activator from Symbiodinium sp.

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