65144-03-8

Usage

Uses

Used in Pharmaceutical Industry:
3-Hydroxystearic acid ethyl ester is used as an intermediate in the synthesis of 3-Hydroxystearoylcarnitine Hydrochloride (H953630), a compound that has been found in overweight patients. This makes it a potential candidate for the development of drugs targeting weight management and obesity-related conditions.
Used in Chemical Synthesis:
3-Hydroxystearic acid ethyl ester can be used as a starting material for the synthesis of various other chemical compounds, such as surfactants, lubricants, and plasticizers. Its unique structure allows for the formation of esters, ethers, and other functional groups, making it a versatile building block in organic chemistry.
Used in Cosmetics and Personal Care Industry:
Due to its solubility and mild properties, 3-Hydroxystearic acid ethyl ester can be used as an ingredient in cosmetics and personal care products. It can act as an emollient, providing a smooth and soft texture to the skin, and can also be used as a solvent for other ingredients in formulations.
Used in Research and Development:
3-Hydroxystearic acid ethyl ester can be utilized in research and development for studying its properties and potential applications. It can be used to investigate the effects of hydroxyl groups on the physical and chemical properties of fatty acid esters, as well as to explore its potential use in various industries, such as pharmaceuticals, cosmetics, and chemical synthesis.

Upstream product

• 64-17-5 ethanol 
• 17773-30-7 3-hydroxyoctadecanoic acid 
• 62625-23-4 ethyl 3-oxooctadecanoate 
• 629-80-1 n-hexadecylaldehyde 
• 105-36-2 ethyl bromoacetate 
• 112-67-4 n-hexadecanoyl chloride 
• 57-10-3 1-hexadecylcarboxylic acid 

Downstream Products

• 2825-79-8 (E)-2-octadecenoic acid 
• 17773-30-7 3-hydroxyoctadecanoic acid 
• 62625-23-4 ethyl 3-oxooctadecanoate 
• 14663-11-7 methyl trans-2-octadecenoate 
• 2831-86-9 trans-octadec-2-en-1-ol 

Relevant academic research and scientific papers

Synthesis of Long-Chain β-Lactones and Their Antibacterial Activities against Pathogenic Mycobacteria

In the quest for new antibacterial agents, a series of novel long- and medium-chain mono- and disubstituted β-lactones was developed. Their activity against three pathogenic mycobacteria—M. abscessus, M. marinum, and M. tuberculosis—was assessed by the resazurin microtiter assay (REMA). Among the 16 β-lactones synthesized, only 3-hexadecyloxetan-2-one (VM005) exhibited promising activity against M. abscessus, whereas most of the β-lactones showed interesting activities against M. marinum, similar to that of the classical antibiotic, isoniazid. Regarding M. tuberculosis, six compounds were found to be active against this mycobacterium, with β-lactone VM008 [trans-(Z)-3-(hexadec-7-en-1-yl)-4-propyloxetan-2-one] being the best growth inhibitor. The promising antibacterial activities of the best compounds in this series suggest that these molecules may serve as leads for the development of much more efficient antimycobacterial agents.

Method for preparation of sphingoid bases

The present invention provides a series of non-toxic compounds which function to inhibit the activity of S-1-P aldolase in respect to its cleavage of S-1-P. These inhibitors are described by the compounds of formula I STR1 wherein R is a radical containing 1 to 15 carbon atoms, a halogen, or hydrocarbon, R' is an organic radical or hydrogen, and R" is --NH3+ or --NH--NH +, with the proviso that, when R is CH3 (CH)12 (CH=CH) and R' is hydrogen, R" is --NH--NH3+. A method for preparing such compounds, which may generally be described as 1-phosphate derivatives of compounds which include a 2-amino-1,3-alcohol radical is also disclosed.