42955-73-7

Basic information

• Product Name: 4-NITROACRIDINE
• Synonyms: 4-NITROACRIDINE;4-Nitroacridine 97%
• CAS NO: 42955-73-7
• Molecular Formula: C₁₃H₈N₂O₂
• Molecular Weight: 224.21
• Mol File: 42955-73-7.mol

Chemical Properties

• Boiling Point: 424.1 °C at 760 mmHg
• Flash Point: 210.3 °C
• Appearance: /
• Density: 1.377 g/cm³
• Vapor Pressure: 5.25E-07mmHg at 25°C
• Refractive Index: 1.754
• CAS DataBase Reference: 4-NITROACRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-NITROACRIDINE(42955-73-7)
• EPA Substance Registry System: 4-NITROACRIDINE(42955-73-7)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 42955-73-7(Hazardous Substances Data)

Usage

Uses

Used in Dye and Pigment Synthesis:
4-Nitroacridine is used as a chemical intermediate for the synthesis of dyes and pigments, leveraging its yellow coloration properties to create a range of colorants for various applications.
Used in Pharmaceutical Synthesis:
In the pharmaceutical industry, 4-Nitroacridine serves as a key intermediate in the production of certain drugs, capitalizing on its chemical structure to develop new therapeutic agents.
Used in Organic Light-Emitting Diodes (OLEDs):
4-Nitroacridine is utilized in the development of organic light-emitting diodes due to its electronic and optical properties, contributing to the advancement of display and lighting technologies.
Used as an Antitumor Agent:
4-Nitroacridine is studied for its potential as an antitumor agent, with research focusing on its cytotoxic effects against cancer cells, offering a possible avenue for cancer treatment.
Used in Antimicrobial and Antiviral Research:
4-NITROACRIDINE is also investigated for its antimicrobial and antiviral activities, exploring its ability to combat infections and contributing to the development of new antimicrobial and antiviral agents.

InChI:InChI=1/C13H8N2O2/c16-15(17)12-7-3-5-10-8-9-4-1-2-6-11(9)14-13(10)12/h1-8H

Upstream product

• 89-98-5 2-chloro-benzaldehyde 
• 88-74-4 2-nitro-aniline 
• 577-19-5 2-nitrophenyl bromide 
• 529-23-7 o-aminobenzaldehyde 
• 260-94-6 acridine 
• 7697-37-2 nitric acid 
• 98-95-3 nitrobenzene 
• 28948-44-9 2-(2-nitro-anilino)-benzaldehyde 
• 6630-33-7 ortho-bromobenzaldehyde 
• 225640-26-6 4-nitro-acridine-9-carbonitrile 
• 5326-19-2 acridine-9-carbonitrile 
• 1207-69-8 9-Chloroacridine 
• 92-81-9 acridine 

Downstream Products

• 578-07-4 4-aminoacridine 

Relevant articles and documents

1,2-Dihydro-1-hydroxy-2,3,1-benzodiazaborine Bearing an Acridine Moiety as a Circular Dichroism Probe for Determination of Absolute Configuration of Mono-Alcohols

A new chiral probe molecule for mono-alcohols is developed by using 1,2-dihydro-1-hydroxy-2,3,1-benzodiazaborine (DAB) bearing an acridine moiety 1. In the presence of mono-alcohols, DAB 1 forms borate 2 by boronic ester formation, followed by coordination of the acridine moiety to the boron atom. Borate 2 has a chiral center on the boron atom and works as a stereodynamic circular dichroism (CD) probe molecule for chiral mono-alcohols based on the π–π interaction between the acridine moiety and the carbon–carbon unsaturated moiety on mono-alcohols.

Investigation on the photoreactions of nitrate and nitrite ions with selected azaarenes in water

The photoreactions of selected azaarenes with nitrate and nitrite ions were investigated under irradiation at λ = 313 nm. The excitation of both anions leads to several photochemical reactions forming mainly hydroxyl radicals and nitrogen oxides. The purification capability of natural waters i.e. the oxidation of inorganic and organic substances results from the formation of hydroxyl radicals. Nitrated isomers of azaarenes were found among the main products of the investigated photoreactions. The nitrogen oxides were responsible for the production of nitrated derivatives which possess a high toxic potential. Their formation was explained by the parallel occurance of two mechanism, a molecular and a radical one. The molecular mechanism became more important with increasing ionisation potentials of the azaarenes. The spectrum of oxidized products corresponded to the one got in the photoreactions of azaarenes with hydrogen peroxide. The formation of several oxidation and nitration products of the pyridine ring with its low electron density was explained by the reaction of excited states of azaarenes. The photoreactions with nitrite ions only led to the formation of oxidized and nitrated products. Nitroso products were not formed. The reactivity of nitrogen monoxide is too low for its reaction with the azaarenes.