5326-19-2

Basic information

• Product Name: acridine-9-carbonitrile
• CAS NO: 5326-19-2
• Molecular Formula: C₁₄H₈N₂
• Molecular Weight: 204.2267
• Mol File: 5326-19-2.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 424.9°C at 760 mmHg
• Flash Point: 139.2°C
• Density: 1.26g/cm³
• Vapor Pressure: 2E-07mmHg at 25°C
• Refractive Index: 1.728
• CAS DataBase Reference: acridine-9-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: acridine-9-carbonitrile(5326-19-2)
• EPA Substance Registry System: acridine-9-carbonitrile(5326-19-2)

Safety Data

• Hazardous Substances Data: 5326-19-2(Hazardous Substances Data)

Usage

General Description

Acridine-9-carbonitrile is a chemical compound with the molecular formula C14H9N. It is a derivative of acridine and contains a cyano group, also known as a nitrile group, attached to the ninth carbon atom of the acridine ring. acridine-9-carbonitrile is a yellow to brown solid and is often used in organic synthesis as a building block for the preparation of various heterocyclic compounds. It is also known to exhibit biological activities, such as antibacterial and antitumor properties, making it of interest for potential pharmacological applications. Acridine-9-carbonitrile is relatively stable and can be handled and stored under normal laboratory conditions.

Upstream product

• 1207-69-8 9-Chloroacridine 
• 143-33-9 sodium cyanide 
• 10228-90-7 9-methoxyacridine 
• 74-90-8 hydrogen cyanide 
• 68818-77-9 9,10-dihydro-acridine-9-carbonitrile 
• 151-50-8 potassium cyanide 
• 611-64-3 9-methyl-acridine 
• 260-94-6 acridine 
• 7677-24-9 trimethylsilyl cyanide 
• 857814-50-7 2,2'-dianilino-bibenzyl-α,α'-diol 
• 6540-78-9 acridine-9-thione 
• 140-29-4 phenylacetonitrile 
• 98-95-3 nitrobenzene 
• 64-17-5 ethanol 

Downstream Products

• 37070-64-7 acridin-9-yl(phenyl)methanone 
• 35417-96-0 acridine-9-carboxylic acid amide 
• 42955-73-7 4-Nitroacridine 
• 5796-81-6 acridin-9-yl-phenyl ketone-imine 

Relevant articles and documents

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Regioselective direct oxidative C-H cyanation of quinoline and its derivatives catalyzed by vanadium-containing heteropoly acids

A direct oxidative C-H cyanation of quinoline and its derivatives using trimethylsilyl cyanide as the cyano source and molecular oxygen as the terminal oxidant has been developed. In the presence of catalytic amounts of vanadium-containing heteropoly acids, e.g., H7PV4Mo8O40, cyanation of various quinoline and its derivatives preferentially took place at the 4-position, affording the corresponding substituted 4-cyanoquinolines as the major products.

Preparation of Heteroarenecarbonitriles by Reaction of Haloheteroarenes with Potassium Cyanide Catalyzed by Sodium p-Toluenesulfinate

Several heteroarenecarbonitriles were prepared by reaction of haloheteroarenes with potassium cyanide catalyzed by sodium p-toluenesulfinate (1) or sodium methanesulfinate (2).In the reaction pathway, the cyanation proceeds through the formation of the su