Synthesis of diverse indole libraries on polystyrene resin - Scope and limitations of an organometallic reaction on solid supports
The synthesis of diverse substituted indole structures on solid supports is described. The immobilization of nitrobenzoic acid onto Merrifield resin and the subsequent treatment with alkenyl Grignard reagents delivered indole carboxylates bound to solid s
Knepper, Kerstin,Vanderheiden, Sylvia,Braese, Stefan
experimental part
p. 1191 - 1199
(2012/09/07)
Practical synthesis and elaboration of methyl 7-chloroindole-4-carboxylate
A synthesis of a previously unknown indole derivative is presented. The route reported herein allows for the preparation of multihundred gram quantities of material without any chromatographic purification. Conditions are presented for the Pd-catalyzed el
Alper, Phil B.,Nguyen, KhanhLinh T.
p. 2051 - 2053
(2007/10/03)
Bartoli indole synthesis on solid supports
(Matrix presented) Bartoli indole synthesis has been performed for the first time on solid supports. Starting from Merrifield resin, immobilization of five nitro benzoic acids was performed. Addition of four different alkenyl Grignard reagents and basic c
Knepper, Kerstin,Braese, Stefan
p. 2829 - 2832
(2007/10/03)
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