56158-78-2Relevant articles and documents
Synthesis, Antimicrobial and Anticancer Evaluation of 2-Azetidinones Clubbed with Quinazolinone
Deep, Aakash,Kumar, Pradeep,Narasimhan, Balasubrmanian,Meng, Lim Siong,Ramasamy, Kalavathy,Mishra, Rakesh Kumar,Mani, Vasudevan
, p. 24 - 28 (2016/07/26)
A novel series of 2-azetidinones clubbed with quinazolinone was synthesized using anthranilic acid. All the synthesized compounds were evaluated for their antimicrobial activity against two Gram positive bacterial strains (Bacillus subtilis and Staphyloco
Synthesis and pharmacological investigation of some novel 2,3-disubstituted quinazolin-4(3H)-ones as analgesic and antiinflammatory agents
Alagarsamy,Meena,Vijayakumar,Ramseshu,Revathi
, p. 233 - 236 (2007/10/03)
A series of novel 2-substituted quinazolin-4(3H)-ones have been synthesized by condensing the aromatic primary amine of 2-substituted quinazolines with different aldehydes and ketones. The synthesized compounds were confirmed by their spectral data (IR, N
Synthesis of certain 3-aminoquinazolinone Schiff's bases structurally related to some biologically active compounds.
Roshdy,Ghoneim,Khalifa
, p. 210 - 213 (2007/10/08)
The condensation of 2-methyl-3-amino-4(3H)-quinazolinone and 2-phenyl-3-amino-4(3H)-quinazolinone with different aldehydes is described. Reacting equimolecular amounts of these two amino compounds with p-nitrobenzaldehyde, p-hydroxybenzaldehyde, cinnamaldehyde and 5-nitro-2-furfuraldehyde diacetate afforded the respective Schiff's bases. Condensation of benzaldehyde, anisaldehyde, p-dimethylaminobenzaldehyde and o-nitrobenzaldehyde with the former quinazolinone afforded the corresponding condensation products while with the latter no condensation took place. Furthermore, condensation of cinnamaldehyde with methylaminoquinazolinone in pyridine and in glacial acetic acid afforded the mono- and di-condensation products respectively while furfural, thiophenaldehyde, resorcinaldehyde, protocatechualdehyde, veratraldehyde, and salicylaldehyde, the condensation ended in failure.