606-41-7

Basic information

• Product Name: 2-amino-1-naphthol
• Synonyms: 2-amino-1-naphthol;2-Amino-1-naphthalenol;2-Aminonaphthalen-1-ol
• CAS NO: 606-41-7
• Molecular Formula: C₁₀H₉NO
• Molecular Weight: 159.18456
• EINECS: 210-117-0
• Mol File: 606-41-7.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-amino-1-naphthol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-amino-1-naphthol(606-41-7)
• EPA Substance Registry System: 2-amino-1-naphthol(606-41-7)

Safety Data

• Hazardous Substances Data: 606-41-7(Hazardous Substances Data)

Usage

Uses

Used in Dye Production:
2-amino-1-naphthol is used as a key intermediate in the production of dyes, specifically azo dyes, due to its ability to easily undergo diazotization and coupling reactions, resulting in a wide range of colorants.
Used in Pharmaceutical Manufacturing:
2-amino-1-naphthol is used as a building block in the synthesis of various pharmaceuticals, contributing to the development of new drugs and medications.
Used as a Reagent in Organic Synthesis:
2-amino-1-naphthol serves as a reagent in organic synthesis, facilitating various chemical reactions and processes in the laboratory and industrial settings.
It is important to handle 2-amino-1-naphthol with care, as it can be toxic and poses potential health hazards if not used properly.

InChI:InChI=1/C10H9NO/c11-9-6-5-7-3-1-2-4-8(7)10(9)12/h1-6,12H,11H2

Upstream product

• 879-15-2 2-diazo-1,2-naphthoquinone 
• 132-53-6 2-Nitroso-1-naphthol 
• 607-24-9 2-nitro-1-naphthol 
• 573-07-9 2-amino-1-naphthol-5-sulfonic acid 
• 6373-60-0 1,2-naphthoquinone-2-oxime 
• 100-63-0 phenylhydrazine 
• 71-43-2 benzene 
• 5099-03-6 2-(4-Methoxy-phenylazo)-[1]naphthol 
• 3375-23-3 2-phenylazo-1-naphthol 
• 581-89-5 2-nitronaphthalene 
• 91-59-8 naphthalen-2-ylamine 
• 7647-01-0 hydrogenchloride 
• 607-27-2 2-(2-(4-nitrophenyl)diazenyl)naphth-1-ol 
• 5577-38-8 2-o-Tolylazo-[1]naphthol 

Downstream Products

• 605-92-5 1-Hydroxy-2-amino-naphthalin-O-sulfonsaeure 
• 97283-42-6 2-phenyl-2,3-dihydro-naphtho[2,1-d][1,3,2]oxazaborole 
• 3608-49-9 2-(4-chloro-phenyl)-naphtho[2,1-d]oxazole 
• 3574-03-6 2-phenylnaphthylene<2.1-d>oxazole 
• 16155-58-1 2-p-tolyl-naphtho[2,1-d]oxazole 
• 22613-28-1 2-biphenyl-4-yl-naphtho[2,1-d]oxazole 
• 60350-54-1 N,N-dimethyl-4-naphtho[2,1-d]oxazol-2-yl-aniline 
• 103086-28-8 2-(2-chloro-5-nitrobenzamido)-1-naphthol 
• 127827-78-5 1,3,5-naphth0<2,1-b>oxadiazepin-4-one 
• 879-15-2 2-diazo-1,2-naphthoquinone 
• 72771-50-7 N-(1-hydroxy-[2]naphthyl)-benzamide 
• 54073-91-5 2-methoxy-1-nitro-6-styryl-14H-naphtho[2',1':5,6][1,4]oxazino[2,3-c]quinoline 
• 16256-12-5 2-[4-(trans-2-biphenyl-4-yl-vinyl)-phenyl]-naphtho[2,1-d]oxazole 
• 41014-42-0 2-chloromethyl-naphtho[2,1-d]oxazole 

Relevant articles and documents

Degradation of azo dye, acid red-14 by hexacyanoferrate(III) using iridium nanoclusters: A kinetic study

In the present work, a novel method for the treatment of wastewater containing an azo dye, acid red-14 by hexacyanoferrate [HCF(III)] in presence of iridium nanoclusters has been proposed. The effect of some important operational parameters such as pH, temperature and catalyst concentration (iridium nano) has been investigated by kinetic spectrophotometric method at λmax 515 nm of the reaction mixture. The results reveal that degradation kinetics of acid red-14 follows first order kinetic model with respect to [HCF(III)], [acid red-14] and Ir nano concentration. Iridium nanoclusters were recovered with the help of centrifugation and reused for three consecutive cycles. Thermodynamic parameters Ea, ΔS#, ΔF#, ΔH# and 'A' have been calculated by studying the reaction rate in the range of temperatures 40 to 55 °C. The formation of degradation products was characterized by chromatographic and spectroscopic techniques after the extraction with ethyl acetate. 1-Hydroxy-2-amino naphthalene and naphthalene sodium sulphate were identified as major degradation products. The results can provide fundamental knowledge for the treatment of wastewater containing acid red-14/other azo dyes.

Antitumor agents. 5. Synthesis, structure - activity relationships, and biological evaluation of dimethyl-5H-pyridophenoxazin-5-ones, tetrahydro-5H-benzopyridophenoxazin-5-ones, and 5H-benzopyridophenoxazin-5-ones with potent antiproliferative activity

New antiproliferative compounds, dimethyl-5H-pyrido[3,2-a]phenoxazin-5-ones (1-6), tetrahydro-5H-benzopyrido[2,3-j]phenoxazin-5-ones (7-9), and 5H-benzopyrido[3,2-a]phenoxazin-5-ones (10-12) were synthesized and evaluated against representative human neoplastic cell lines. Dimethyl derivatives 1-6 were more active against carcinoma than leukemia cell lines. The tetrahydrobenzo derivatives 7-9 were scarcely active, whereas the corresponding benzo derivatives 10-12 showed notable cytotoxicity against a majority of the tested cell lines. Molecular modeling studies indicated that the high potency of 10 and 11, the most cytotoxic compounds of the whole series, could be due to the position of the condensed benzene ring, which favors π-π stacking interactions with purine and pyrimidine bases in the DNA active site. Biological studies suggested that 10-12 have no effect on human topoisomerases I and II and that they induce arrest at the G2/M phase.

Regio- and chemoselective catalytic transfer hydrogenation of aromatic nitro and carbonyl as well as reductive cleavage of azo compounds over novel mesoporous NiMCM-41 molecular sieves

(equation presented) Regio-and chemoselective reduction of nitroarenes and carbonyl compounds and reductive cleavage of azo compounds, including bulkier molecules, was achieved by the catalytic transfer hydrogenation method (CTH) using a novel nickel-containing mesoporous silicate (NiMCM-41) molecular sieve catalyst. In addition, the catalyst was also found to behave as a truly heterogeneous catalyst as the yield was practically unaffected.

Kinetics of Hydrolysis of Some New Heterocyclic Azomethines

Kinetics of base hydrolysis of new heterocyclic azomethines derived from active methyl quaternary salts and aromatic nitroso compounds were investigated in the presence of 70percent (wt/wt) water-methanol.The base hydrolysis of these compounds is strictly first-order with respect to OH- and azomethine.The rate determining step is suggested to be the attack of the hydroxide ion on the free base.Effects of water content and nature of organic hydroxylic solvent have been studied.It is concluded that specific solute-solvent interactions through dispersion forces play a major role in the base hydrolysis rate of the azomethines investigated.The effect of pH (2.98 - 12.24) on hydrolysis rates of compounds having a diethylamino substituent in the presence of 30percent methanol has been studied.In acidic media, the rate determining step is probably the water attack on the protonated substrate.

Method for preparing adduct of butadiene polymer or copolymer and α, β-ethylenically unsaturated dicarboxylic acid compound

In a method for preparing an adduct of (A) a butadiene lower polymer or butadiene lower copolymer and (B) a α,β-ethylenically unsaturated dicarboxylic acid compound, said method is characterized in that said (A) and (B) are caused to react in the presence of one or more compounds selected from (C) p-phenylenediamine derivatives, catechol derivatives, pyrogallol derivatives, N-nitrosamines, quinoline derivatives and naphthol derivatives, thus serious increase of the viscosity of said adduct in the addition reaction can be prevented.