67568-30-3

Basic information

• Product Name: 3-AMINOQUINOXALINE-2-CARBOXAMIDE
• Synonyms: 3-AMINOQUINOXALINE-2-CARBOXAMIDE;3-Amino-2-quinoxalinecarboxamide
• CAS NO: 67568-30-3
• Molecular Formula: C₉H₈N₄O
• Molecular Weight: 188.19
• Mol File: 67568-30-3.mol

Chemical Properties

• Boiling Point: 403.8 °C at 760 mmHg
• Flash Point: 198 °C
• Appearance: /
• Density: 1.436 g/cm³
• Vapor Pressure: 9.88E-07mmHg at 25°C
• Refractive Index: 1.751
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 3-AMINOQUINOXALINE-2-CARBOXAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-AMINOQUINOXALINE-2-CARBOXAMIDE(67568-30-3)
• EPA Substance Registry System: 3-AMINOQUINOXALINE-2-CARBOXAMIDE(67568-30-3)

Safety Data

• Hazardous Substances Data: 67568-30-3(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
3-Aminoquinoxaline-2-carboxamide is used as a potential anticancer agent for its ability to target and treat cancer cells. It is also utilized as a building block in the synthesis of various pharmacologically active compounds, contributing to the development of new medications.
Used in Organic Synthesis:
3-Aminoquinoxaline-2-carboxamide serves as a key component in the creation of complex organic molecules, playing a crucial role in advancing chemical research and the production of specialty chemicals.
Used in Antimicrobial Applications:
3-Aminoquinoxaline-2-carboxamide is used as an antibacterial and antifungal agent, leveraging its properties to combat microbial infections and contributing to the field of infectious disease management.

InChI:InChI=1/C9H8N4O/c10-8-7(9(11)14)12-5-3-1-2-4-6(5)13-8/h1-4H,(H2,10,13)(H2,11,14)

Upstream product

• 49679-45-0 ethyl 3-chloroquinoxaline-2-carboxylate 
• 1204-75-7 3-hydroxyquinoxaline-2-carboxylic acid 
• 21580-62-1 2-carbomethoxy-3-hydroxyquinoxaline 
• 1085940-92-6 methyl 3-chloroquinoxaline-2-carboxylate 
• 95-54-5 1,2-diamino-benzene 
• 36818-07-2 ethyl 3-oxo-4H-quinoxaline-2-carboxylate 
• 23395-75-7 ethyl 2-quinoxalinecarboxylate 4-oxide 
• 23190-84-3 2-cyano-3-amino-quinoxaline-di-N-oxide 
• 480-96-6 benzofurazan oxide 
• 36597-16-7 3-amino-2-quinoxalinecarbonitrile 
• 23280-20-8 2-Amino-3-carboxamidoquinoxaline 1,4-di-N-oxide 

Downstream Products

• 1085940-95-9 3-benzyl-2-isobutylbenzo[g]pteridin-4(3H)-one 
• 1085940-96-0 3-benzyl-2-(1-bromo-2-methyl-propyl)-3H-benzo[g]pteridin-4-one 
• 1085940-97-1 {3-[1-(3-Benzyl-4-oxo-3,4-dihydro-benzo[g]pteridin-2-yl)-2-methyl-propylamino]-propyl}-carbamic acid tert-butyl ester 
• 1085940-98-2 C₃₇H₄₂N₆O₄ 
• 490-59-5 alloxazine 
• 85414-82-0 2-aminoquinoxaline-3-carboxylic acid 

Relevant articles and documents

AMINO-QUINOXALINE AND AMINO-QUINOLINE COMPOUNDS FOR USE AS ADENOSINE A2A RECEPTOR ANTAGONISTS

Compounds of the Formula (I), where W represents CH or N; and Q represents -CN, -C(=NOH)NH2, -CONHR1 or various herein described heterocyclic radicals; as well as pharmaceutically acceptable salts, solvates, esters and prodrugs thereof are adenosine A2a receptor antagonists and, therefore, are useful in the treatment of central nervous system diseases, in particular Parkinson''s disease.

KINESIN INHIBITORS

This invention relates to the compounds of formula (I) shown below. Each variable in formula (I) is defined in the specification. These compounds can be used to treat a kinesin Eg5 protein-mediated disorder.

Composition of matter having bioactive properties

Particles of coordinated complex comprising a basic, hydrous polymer and a capacitance adding compound, as well as methods for their production, are described. These complexes exhibit a high degree of bioactivity making them suitable for a broad range of applications through their incorporation into conventional vehicles benefiting from antimicrobial and similar properties.

3-Amino-2-quinoxalinecarbonitrile. New fused quinoxalines with potential cytotoxic activity

Starting with 3-amino-2-quinoxalinecarbonitrile 1,4-dioxide 1, a new series of quinoxaline derivatives was prepared through chemical modifications of the 2-cyano and 3-amino groups. Nitration of 3-amino-2-quinoxalinecarbonitrile 3 afforded the 7-nitro derivative 6. Diazotation of 3 gave the 3-chloro compound 9. 2,3-Quinoxalinedicarbonitrile 14 was obtained from 9. Pyridazino[4,5-b]quinoxalines 15 and 16 were prepared by condensing 14 with hydrazine hydrate. A triazolo[4,5-b]quinoxaline 18, a isothiazolo[4,5-b]quinoxaline 20 and two pyrazolo[3,4-b]quinoxalines 21 and 22 were identified. Compounds were tested as cytotoxic agents both in oxic and in hypoxic cells.