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5-bromo-2,4-dimethylphenylamine is an organic chemical compound with the molecular formula C8H10BrN. It is a derivative of aniline, featuring a bromine atom attached to the benzene ring and two methyl groups at the 2 and 4 positions. 5-bromo-2,4-dimethylphenylamine is widely recognized for its versatility in various applications, particularly in the fields of organic synthesis, pharmaceutical research, and materials science.

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  • 69383-60-4 Structure
  • Basic information

    1. Product Name: 5-bromo-2,4-dimethylphenylamine
    2. Synonyms: 5-bromo-2,4-dimethylphenylamine;4-BROMO-6-AMINO-M-XYLENE;4-Amino-6-bromo-m-xylene;4-Amino-6-bromo-m-xylene, 5-Bromo-2,4-xylidine;NSC 159240
    3. CAS NO:69383-60-4
    4. Molecular Formula: C8H10BrN
    5. Molecular Weight: 200.078
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 69383-60-4.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 274.8°Cat760mmHg
    3. Flash Point: 120°C
    4. Appearance: /
    5. Density: 1.424g/cm3
    6. Vapor Pressure: 0.00528mmHg at 25°C
    7. Refractive Index: 1.596
    8. Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
    9. Solubility: N/A
    10. CAS DataBase Reference: 5-bromo-2,4-dimethylphenylamine(CAS DataBase Reference)
    11. NIST Chemistry Reference: 5-bromo-2,4-dimethylphenylamine(69383-60-4)
    12. EPA Substance Registry System: 5-bromo-2,4-dimethylphenylamine(69383-60-4)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 69383-60-4(Hazardous Substances Data)

69383-60-4 Usage

Uses

Used in Organic Synthesis:
5-bromo-2,4-dimethylphenylamine is used as a reagent in organic synthesis for its ability to participate in a range of chemical reactions, facilitating the creation of diverse organic compounds.
Used in Pharmaceutical Research:
In pharmaceutical research, 5-bromo-2,4-dimethylphenylamine is utilized as a key intermediate in the synthesis of various pharmaceuticals, contributing to the development of new drugs and therapeutic agents.
Used in Agrochemicals:
5-bromo-2,4-dimethylphenylamine is employed in the synthesis of agrochemicals, playing a crucial role in the development of pesticides and other agricultural chemicals to enhance crop protection and yield.
Used in Materials Science:
5-bromo-2,4-dimethylphenylamine is also used in materials science for the production of dyes and organic pigments, where its unique chemical structure imparts specific color and stability properties to the final products.
Used in Medicine and Biochemistry:
Due to its unique properties and chemical structure, 5-bromo-2,4-dimethylphenylamine has potential applications in medicine and biochemistry, where it may be involved in the study of biological processes or the development of novel bioactive compounds.

Check Digit Verification of cas no

The CAS Registry Mumber 69383-60-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,9,3,8 and 3 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 69383-60:
(7*6)+(6*9)+(5*3)+(4*8)+(3*3)+(2*6)+(1*0)=164
164 % 10 = 4
So 69383-60-4 is a valid CAS Registry Number.
InChI:InChI=1/C8H10BrN/c1-5-3-6(2)8(10)4-7(5)9/h3-4H,10H2,1-2H3

69383-60-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-Bromo-2,4-dimethylaniline

1.2 Other means of identification

Product number -
Other names 5-bromo-2,4-dimethylaniline

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:69383-60-4 SDS

69383-60-4Relevant articles and documents

Discovery of aryl aminothiazole γ-secretase modulators with novel effects on amyloid β-peptide production

Bhattarai, Sanjay,Liu, Lei,Wolfe, Michael S.

supporting information, (2021/11/16)

A series of analogs based on a prototype aryl aminothiazole γ-secretase modulator (GSM) were synthesized and tested for their effects on the profile of 37-to-42-residue amyloid β-peptides (Aβ), generated through processive proteolysis of precursor protein

Discovery of 4-Aminoquinoline-3-carboxamide derivatives as potent reversible Bruton's tyrosine kinase inhibitors for the treatment of rheumatoid arthritis

Yao, Xia,Sun, Xiuyun,Jin, Shuyu,Yang, Ling,Xu, Hongjiang,Rao, Yu

, p. 6561 - 6574 (2019/08/20)

A structure-hopping strategy was applied to discover a series of novel 4-aminoquinoline-3-carboxamide derivatives as potent, reversible BTK inhibitors. Compared to the previously described cinnoline scaffold compounds, the 4-aminoquinoline analogues showed significantly improved drug-like properties, especially in their aqueous solubility. The most potent compound, 25, displayed a stronger inhibitory effect on both BTKWT (IC50 = 5.3 nM) and BTKC481S (IC50 = 39 nM). In a rodent collagen-induced arthritis model, compound 25 efficiently reduced paw swelling without a loss in body weight. On the basis of potency, drug-like properties, stability, and noncovalent mode of inhibition, our representative inhibitors could have a promising profile to be treatments for a wide range of autoimmune diseases.

4,5,6-TRI-SUBSTITUTED INDAZOLES DERIVATIVES, PREPARATION THEREOF, AND USE THEREOF IN MEDICINES

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Paragraph 0110-0111, (2019/02/19)

Provided are 4,5,6-tri-substituted indazoles derivatives, a preparation method therefor, and a use thereof in medicines. Specifically, provided are compounds of formula (I) or pharmaceutically acceptable salts, stereoisomers, solvates, or prodrugs thereof

THIOPHENE-2-CARBOXAMIDE DERIVATIVES AS MODULATORS OF CCR9 RECEPTOR

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Page/Page column 42-43, (2009/05/29)

Provided are compounds of Formula (I) or of Formula (II) that are modulators of CCR9 receptor activity, compositions containing the compounds and methods of use of the compounds and compositions. In certain embodiments, provided are methods for treating or amelioratin diseases associated with modulation of CCR9 receptor activity.

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