69644-78-6

Basic information

• Product Name: BIS-ACV
• Synonyms: (H-AAD(CYS-D-VAL-OH)-OH)2;BIS-DELTA-(L-ALPHA-AMINOADIPYL)-L-CYSTINYL-BIS-D-VALINE;BIS-ACV;Bis-d-(L-a-aMinoadipyl)-L-cystinyl-bis-D-valine
• CAS NO: 69644-78-6
• Molecular Formula: C28H48N6O12S2
• Molecular Weight: 724.84
• Mol File: 69644-78-6.mol

Chemical Properties

• Appearance: /
• Storage Temp.: −20°C
• CAS DataBase Reference: BIS-ACV(CAS DataBase Reference)
• NIST Chemistry Reference: BIS-ACV(69644-78-6)
• EPA Substance Registry System: BIS-ACV(69644-78-6)

Safety Data

• Safety Statements: 22-24/25
• WGK Germany: 3
• Hazardous Substances Data: 69644-78-6(Hazardous Substances Data)

Usage

Uses

Used in Polymer and Hydrogel Manufacturing:
BIS-ACV is used as a crosslinking agent for strengthening the structure of polymers and hydrogels by forming covalent bonds between polymer chains, which improves the material's stability and performance.
Used in Biomedical Applications:
In the biomedical industry, BIS-ACV is used as a component in drug delivery systems to enhance the controlled release of therapeutic agents, and in tissue engineering to support the growth and development of artificial tissues.
Used in DNA Analysis and Biological Research:
BIS-ACV is utilized in DNA analysis and other biological research applications, where its chemical properties contribute to advancements in understanding and manipulating biological systems.

Upstream product

• 79761-05-0 N-benzyloxycarbonyl-α-benzyl-δ-(L-α-aminoadipoyl)-S-benzyl-L-cysteinyl-D-valine benzyl ester 
• 24325-17-5 N-benzyloxycarbonyl-α-benzylester-δ-L-α-aminoadipic acid 
• 24325-14-2 (2S)-2-[(phenylmethoxy)carbonyl]aminoadipic acid 
• 87141-23-9 p-nitrobenzyl N-benzyloxycarbonyl-L-α-aminoadipate 
• 87141-25-1 N-benzyloxycarbonyl-1-(p-nitrobenzyl)-δ-(L-α-aminoadipyl)-S-benzyl-L-cysteine, benzhydryl ester 
• 61852-70-8 D-valine, benzhydryl ester 
• 123872-88-8 (R)-2-((R)-2-Amino-3-benzylsulfanyl-propionylamino)-3-methyl-butyric acid benzyl ester; hydrochloride 
• 109345-41-7 N-(tert-butyloxycarbonyl)-S-benzyl-L-cysteinyl-D-valine benzyl ester 
• 84701-31-5 di-(1-<(1R)-carboxy-2-methylpropyl>-(3R)-<-(5S)-5-amino-5-carboxypentanamido>-(4R)-mercapto azetidin-2-one)disulphide 
• 21566-74-5 (L-α-amino-δ-adipyl)-L-cysteinyl-D-valine 
• 87141-26-2 N-benzyloxycarbonyl-1-(p-nitrobenzyl)-δ-(L-α-aminoadipyl)-S-benzyl-L-cysteine 
• 87141-27-3 N-benzyloxycarbonyl-1-(p-nitrobenzyl)-δ-(L-α-aminoadipyl)-S-benzyl-L-cysteinyl-D-valine, benzhydryl ester 

Downstream Products

• 21566-74-5 (L-α-amino-δ-adipyl)-L-cysteinyl-D-valine 

Relevant articles and documents

EFFICIENT ROUTES TO THE ARNSTEINS'S TRIPEPTIDE δ-(L-α-AMINOADIPYL)-L-CYSTEINYL-D-VALINE (LLD ACV) FROM THE OXIDATION PRODUCTS OF L-LYSINE DERIVATIVES

Two efficient syntheses of the linear tripeptide precursor of penam and cephem antibiotics are presented.The routes are characterised by the use of L-lysine derivatives, Z-L-Lys(Z)-OH and H-L-Lys(Z)-OH as starting materials.By the permanganate oxidation t

Synthesis of δ-(L-α-Aminoadipyl)-L-cysteinyl-D-valine and δ-(L-α-Aminoadipyl)-L-cysteinyl-D-valylglycine

An efficient synthesis of δ-(L-α-aminoadipyl)-L-cysteinyl-D-valine (ACV; 1) and δ-(L-α-aminoadipyl)-L-cysteinyl-D-valylglycine (ACVG; 2) via the protected tripeptide N-benzyloxycarbonyl-1-(p-nitrobenzyl)-δ-(L-α-aminoadipyl)-S-benzyl-L-cysteinyl-D-valine,