71460-02-1

Basic information

• Product Name: (2S)-2-[[(1,1-Dimethylethoxy)carbonyl]amino]-4-pentynoic acid methyl ester
• Synonyms: (2S)-2-[[(1,1-Dimethylethoxy)carbonyl]amino]-4-pentynoic acid methyl ester;(S)-2-(Boc-amino)-4-pentynoic acid methyl ester;Methyl (2S)-2-(tert-butoxycarbonylamino)pent-4-ynoate
• CAS NO: 71460-02-1
• Molecular Formula: C₁₁H₁₇NO₄
• Molecular Weight: 227.25698
• Mol File: 71460-02-1.mol

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: (2S)-2-[[(1,1-Dimethylethoxy)carbonyl]amino]-4-pentynoic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (2S)-2-[[(1,1-Dimethylethoxy)carbonyl]amino]-4-pentynoic acid methyl ester(71460-02-1)
• EPA Substance Registry System: (2S)-2-[[(1,1-Dimethylethoxy)carbonyl]amino]-4-pentynoic acid methyl ester(71460-02-1)

Safety Data

• Hazardous Substances Data: 71460-02-1(Hazardous Substances Data)

Usage

Uses

Used in Bioconjugation:
(2S)-2-[[(1,1-Dimethylethoxy)carbonyl]amino]-4-pentynoic acid methyl ester is used as a building block for the synthesis of diverse peptide and protein conjugates due to its homopropargyl group, which facilitates the formation of stable covalent bonds with other biomolecules.
Used in Click Chemistry:
In the field of chemical biology, (2S)-2-[[(1,1-Dimethylethoxy)carbonyl]amino]-4-pentynoic acid methyl ester is used as a reactant in click chemistry for the efficient and specific ligation of biomolecules, taking advantage of its alkynyl functionality to form stable triazole linkages.
Used in Drug Development:
(2S)-2-[[(1,1-Dimethylethoxy)carbonyl]amino]-4-pentynoic acid methyl ester is utilized as a key component in the design and synthesis of novel drug candidates, where its ability to be selectively deprotected and functionalized contributes to the creation of targeted therapeutic agents.
Used in Materials Science:
In the realm of materials science, (2S)-2-[[(1,1-Dimethylethoxy)carbonyl]amino]-4-pentynoic acid methyl ester is employed as a component in the development of biocompatible and functional materials, leveraging its chemical reactivity and versatility to create advanced material systems.
Used in Research Applications:
Across various research fields, (2S)-2-[[(1,1-Dimethylethoxy)carbonyl]amino]-4-pentynoic acid methyl ester is used as a research tool for exploring new chemical reactions and mechanisms, as well as for the development of innovative methodologies in organic synthesis and bioconjugation.

Upstream product

• 106-96-7 propargyl bromide 
• 173306-81-5 acetyloxy[[(1,1-dimethylethoxy)carbonyl]amino]acetic acid methyl ester 
• 24424-99-5 di-tert-butyl dicarbonate 
• 70837-20-6 propargyclycine methyl ester hydrochloride 
• 150749-03-4 methyl 2-(tert-butoxycarbonylamino)-2-hydroxyacetate 
• 61172-60-9 diethyl α-acetamido-α-propargylmalonate 
• 61172-66-5 (S)-2-(tert-butoxycarbonylamino)pent-4-ynoic acid 
• 74-88-4 methyl iodide 
• 166271-28-9 (S)-1-methoxy-1-oxopent-4-yn-2-aminium chloride 
• 67-56-1 methanol 
• 23235-01-0 (2S)-2-amino-4-pentynoic acid 
• 186581-53-3 diazomethane 
• 101925-55-7 (S)-propargylglycine methyl ester 
• 18107-18-1 diazomethyl-trimethyl-silane 

Downstream Products

• 208709-97-1 2-tert-Butoxycarbonylamino-5-(2,4-difluoro-phenyl)-pent-4-ynoic acid methyl ester 
• 291534-50-4 (+/-)-methyl 2-(tert-butoxycarbonylamino)-5-phenylpent-4-ynoate 
• 540516-91-4 methyl 5-(2-aminophenyl)-2-[(tert-butoxycarbonyl)amino]-4-pentynoate 
• 291533-78-3 Methyl 2-N-boc-amino-5-(4-morpholinophenyl)-pent-4-ynoate 
• 1027075-46-2 (S)-2-((S)-2-Amino-5-phenyl-pent-4-ynoylamino)-4-methyl-pentanoic acid methyl ester 
• 1027888-17-0 (S)-2-[(S)-2-Amino-5-(3-fluoro-phenyl)-pent-4-ynoylamino]-4-methyl-pentanoic acid methyl ester 
• 1026127-32-1 (S)-2-tert-Butoxycarbonylamino-5-(2-fluoro-phenyl)-pent-4-ynoic acid 
• 208709-91-5 (S)-2-[(S)-2-Amino-5-(2-chloro-phenyl)-pent-4-ynoylamino]-4-methyl-pentanoic acid methyl ester 
• 1026941-79-6 (S)-2-[(Dimethoxy-phosphorylmethyl)-amino]-5-(2-fluoro-phenyl)-pent-4-ynoic acid 
• 208709-98-2 (S)-2-tert-Butoxycarbonylamino-5-(2,4-difluoro-phenyl)-pent-4-ynoic acid 
• 208710-05-8 (S)-5-(2,4-Difluoro-phenyl)-2-[(dimethoxy-phosphorylmethyl)-amino]-pent-4-ynoic acid 
• 208710-04-7 (S)-5-(2,4-Difluoro-phenyl)-2-[(dimethoxy-phosphorylmethyl)-amino]-pent-4-ynoic acid methyl ester 
• 1026717-93-0 [(S)-1-(2-Cyano-ethylcarbamoyl)-4-(2-fluoro-phenyl)-but-3-ynyl]-carbamic acid tert-butyl ester 

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