73101-79-8

Basic information

• Product Name: 5-ethoxy-6-methylpyridin-2-amine
• Synonyms: 5-ethoxy-6-methylpyridin-2-amine;6-Amino-3-ethoxy-6-methylpyridine;2-Amino-5-ethoxy-6-methylpyridine
• CAS NO: 73101-79-8
• Molecular Formula: C8H12N2O
• Molecular Weight: 152.19368
• Mol File: 73101-79-8.mol

Chemical Properties

• Boiling Point: 261.3 °C at 760 mmHg
• Flash Point: 111.8 °C
• Appearance: /
• Density: 1.073 g/cm³
• Vapor Pressure: 0.0117mmHg at 25°C
• Refractive Index: 1.543
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• CAS DataBase Reference: 5-ethoxy-6-methylpyridin-2-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 5-ethoxy-6-methylpyridin-2-amine(73101-79-8)
• EPA Substance Registry System: 5-ethoxy-6-methylpyridin-2-amine(73101-79-8)

Safety Data

• Hazardous Substances Data: 73101-79-8(Hazardous Substances Data)

Usage

Uses

Used in Chemical Synthesis:
5-ethoxy-6-methylpyridin-2-amine is used as a building block in the synthesis of organic compounds. Its unique structure allows for the creation of a variety of chemical entities, making it a valuable component in the development of new chemical products.
Used in Pharmaceutical Development:
In the pharmaceutical industry, 5-ethoxy-6-methylpyridin-2-amine is utilized as an intermediate in the production of pharmaceutical drugs. Its presence in the molecular structure can contribute to the drug's efficacy and therapeutic properties.
Used in Agrochemicals and Pesticides:
Due to its chemical properties, 5-ethoxy-6-methylpyridin-2-amine has potential applications in the field of agrochemicals and pesticides. It can be incorporated into formulations to enhance their effectiveness in controlling pests and diseases in agriculture.
Used in Research and Development:
5-ethoxy-6-methylpyridin-2-amine is also employed in research and development for the creation of new materials. Its unique chemical structure offers opportunities for exploration in various scientific fields, contributing to the advancement of knowledge and technology.
It is crucial to handle 5-ethoxy-6-methylpyridin-2-amine with care and follow safety guidelines during its use, as it may pose potential hazards associated with handling and application.

InChI:InChI=1/C8H12N2O/c1-3-11-7-4-5-8(9)10-6(7)2/h4-5H,3H2,1-2H3,(H2,9,10)

Upstream product

• 73101-78-7 3-ethoxy-6-nitro-2-picoline 
• 6652-01-3 3-ethoxy-2-methyl-pyridine 

Downstream Products

• 73101-90-3 5-ethyl-8-oxo-2,3,5,8-tetrahydrofuro<3,2-b><1,8>naphthyridine-7-carboxylic acid 
• 73101-87-8 5-ethyl-8-oxo-5,8-dihydrofuro<3,2-b><1,8>naphthyridine-7-carboxylic acid 
• 83593-35-5 ethyl 6-benzyloxy-1-ethyl-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-7-carboxylate 
• 77016-54-7 3-(6-ethoxy-3-ethoxycarbonyl-4-hydroxy-1,8-naphthyridin-7-yl)acrylic acid 
• 79905-33-2 ethyl 6-benzyloxy-7-(2-dimethylaminovinyl)-1-ethyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylate 
• 79905-34-3 6-benzyloxy-7-(2,2-diethoxyethyl)-1-ethyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid 

Relevant articles and documents

Condensed 4-aminopyridines with antirheumatic activity

Compounds of formula I STR1 and pharmaceutically acceptable salts thereof in which one of A or B represents N and the other represents N or C--R3 ; R1 represents hydrogen, halo, alkyl, hydroxy, carboxyalkenyl, alkoxycarbonylalkenyl, hydroxyalkyl, carboxyalkyl, alkoxycarbonylalkyl, alkoxy, halogenated alkyl, carboxy, alkoxycarbonyl, alkanoylamino or carbamoylalkenyl; R2 represents hydrogen, alkyl, halo, alkoxy, hydroxy, alkanoyloxy, or phenoxy; R3 represents hydrogen or alkyl; R4 represents hydrogen, halo, alkoxycarbonyl, cyano, benzyloxycarbonyl, alkanoyl, benzoyl, alkyl, carboxy, alkylthio or carbamoyl; R5 represents hydrogen or alkyl; R9 represents hydrogen or alkyl; R10 represents phenyl, pyridyl or pyrimidinyl substituted by OR6 and optionally further substituted wherein R6 represents hydrogen, alkyl, alkoxycarbonyl or carbamoyl, alicyclic hydrocarbon, phenyl, cycloalkylalkyl, arylalkyl or pyridyl; or when R10 represents phenyl, OR6 represents a monosaccharide group or a disaccharide group; which are antirheumatic agents. Compositions containing these compounds and processes to prepare them are also disclosed.

Amino naphthyridine compounds as anti-rhoumatic agents

This invention relates to compounds of formula I and pharmaceutically acceptable salts thereof STR1 in which R1 represents hydrogen, alkyl, hydroxy, carboxyalkenyl, alkoxycarbonyalkenyl, hydroxyalkyl, carboxyalkyl, alkoxycarbonylalkyl, alkoxy, halogenated alkyl, carboxy alkoxycarbonyl or alkanoylamino; R2 represents hydrogen, halo, alkoxy, hydroxy, alkanoyloxy, or phenoxy; R3 represents hydrogen or alkyl; R4 represents hydrogen, halo, alkoxycarbonyl, a benzyloxycarbonyl, alkanoyl, benzoyl, carbamoyl, alkyl, carboxy, hydroxyalkyl or alkylthio; R5 represents hydrogen or alkyl; R6 represents hydrogen, alkyl [optionally substituted by one or more of the following: hydroxy, halo or an amino group of formula --NR12 R13 ], a C3-12 alicyclic hydrocarbon group, phenyl, (cycloalkyl)alkyl or benzyl; R7 represents hydrogen, halo, trifluoromethyl, trifluoromethoxy, alkyl, carboxy, or alkoxy; R8 represents hydrogen, halo, trifluoromethyl, trifluoromethoxy, alkyl or alkoxy; and R9 represents hydrogen or alkyl; which are antirheumatic agents. Compositions containing these compounds and processes to make them are also disclosed.

Synthesis of antimicrobial agents. VI. Studies on the synthesis of furo[3,2-b][1,8]naphthyridine derivatives

As a part of our search for new antibacterial agents, 5-ethyl-8-oxo-5,8-dihydrofuro[3,2-b][1,8]naphthyridine-7-carboxylic acid and its 2,3-dihydrofuro derivative, the 4-aza analogue of droxacin, were synthesized and their antibacterial activities were tested. Both compounds exhibited high antibacterial activities and a broad antibacterial spectrum. In an attempt to find a suitable method for industrial-scale synthesis of these compounds, several methods for the furan ring cyclization of 6,7-disubstituted 1,8-naphthyridine-3-carboxylate derivatives were compared.

Furonaphthyridine compounds

2,3,5,8-Tetrahydrofuro- and 5,8-dihydrofuro[3,2-b]-1,8-naphthyridine compounds of the formula (I) STR1 wherein R1 represents an alkyl group having 1 to 6 carbon atoms and M represents a hydrogen atom, an alkali metal or an alkaline earth metal having anti-bacterial activity.