75340-02-2

Basic information

• Product Name: 7-DeMethylrobustigenin
• Synonyms: 7-DeMethylrobustigenin
• CAS NO: 75340-02-2
• Molecular Formula: C₁₈H₁₆O₇
• Molecular Weight: 344.31544
• Product Categories: Aromatics, Miscellaneous Reagents, Pharmaceuticals, Intermediates & Fine Chemicals
• Mol File: 75340-02-2.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 7-DeMethylrobustigenin(CAS DataBase Reference)
• NIST Chemistry Reference: 7-DeMethylrobustigenin(75340-02-2)
• EPA Substance Registry System: 7-DeMethylrobustigenin(75340-02-2)

Safety Data

• Hazardous Substances Data: 75340-02-2(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
7-DeMethylrobustigenin is used as an antiplasmodial agent for its ability to combat plasmodium parasites, which are responsible for causing malaria. Its presence in Erythrina Sacleuxil makes it a potential candidate for developing treatments and therapies against malaria.

Upstream product

• 75340-01-1 5,7-bis(benzyloxy)-2',4',5'-trimethoxyisoflavone 
• 72545-40-5 2',4',6'-trihydroxy-(2,4,5-trimethoxyphenyl)acetophenone 
• 68-12-2 N,N-dimethyl-formamide 
• 108-73-6 3,5-dihydroxyphenol 
• 38444-50-7 2,4,5-trimethoxybenzeneacetonitrile 
• 4460-86-0 asaraldehyde 
• 75340-00-0 4,6-bis(benzyloxy)-2-hydroxy-2',4',5'-trimethoxydeoxybenzoin 

Downstream Products

• 72545-41-6 2',4',5,5',7-pentamethoxyisoflavone 
• 1446307-18-1 7-(1,1-dimethylpropargyloxy)-5-hydroxy-2',4',5'-trimethoxyisoflavone 
• 58084-83-6 2',4',5,5'-tetramethoxy-2,2-dimethylpyrano<5,6-g>isoflavone 
• 1446307-19-2 C₂₂H₁₈O₇ 
• 58084-82-5 C₂₃H₂₂O₇ 
• 3044-60-8 5-hydroxy-2',4',5'-trimethoxy-2,2-dimethylpyrano<6,5-h>isoflavone 

Relevant articles and documents

Studies on the total synthesis of Hirtellanine A: Regioselective synthesis of benzopyran

The total synthesis of Hirtellanine A was accomplished by two different synthetic approaches. Hirtellanine A was assembled using a one-pot, tandem acid-mediated deprotection and tautomerization cascade starting from quinone derivative 23. The key features

Synthesis of 5,7-Dihydroxy-2',4',5'-trimethoxyisoflavone and Its 7-Methyl Ether (Robustigenin)

The treatment of 2,4,6-trihydroxy-2',4',5'-trimethoxydeoxybenzoin with benzyl chloride gave a dibenzyl ether.The condensation of the ether with ethyl formate, followed by the debenzylation of the resulting isoflavone, afforded 5,7-dihydroxy-2',4',5'-trimethoxyisoflavone, which was then converted into a pentamethoxyisoflavone.The partial demethylation of the pentamethoxyisoflavone gave 5-hydroxy-2',4',5',7'-tetramethoxyisoflavone, which was identical with natural robustigenin.