81038-28-0

Basic information

• Product Name: 4-nitro-1-tosylindol
• Synonyms: 4-nitro-1-tosylindol
• CAS NO: 81038-28-0
• Molecular Formula: C₁₅H₁₂N₂O₄S
• Molecular Weight: 316
• Mol File: 81038-28-0.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-nitro-1-tosylindol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-nitro-1-tosylindol(81038-28-0)
• EPA Substance Registry System: 4-nitro-1-tosylindol(81038-28-0)

Safety Data

• Hazardous Substances Data: 81038-28-0(Hazardous Substances Data)

Upstream product

• 4769-97-5 4-nitro-1H-indoIe 
• 98-59-9 p-toluenesulfonyl chloride 
• 78283-23-5 4-nitro-1-hydroxyindole 
• 81038-27-9 methyl 2-hydroxy-2-(4-nitroindol-1-yl)-acetate 
• 81038-26-8 methyl 2-(4-nitroindole-1-yl)oxyacetate 

Downstream Products

• 81038-31-5 1-tosyl-1H-indol-4-amine 
• 2380-94-1 1H-indol-4-ol 
• 1322744-58-0 (S)-2-benzyloxycarbonylamino-3-[4-nitro-1-(toluene-4-sulfonyl)-1H-indol-3-yl]propionic acid methyl ester 
• 1322744-50-2 3-bromo-4-nitro-1-(toluene-4-sulfonyl)-1H-indole 
• 1446428-09-6 1-tosyl-4-(trifluoromethyl)-1H-indole 

Relevant articles and documents

Silver-mediated trifluoromethylation of aryldiazonium salts: Conversion of amino group into trifluoromethyl group

A novel strategy for aromatic trifluoromethylation by converting aromatic amino group into CF3 group is reported herein. This method, which can be considered as trifluoromethylation variation of the classic Sandmeyer reaction, uses readily available aromatic amines as starting materials and is performed under mild conditions.

Convenient synthesis of chiral tryptophan derivatives using Negishi cross-coupling

A facile synthetic procedure for chiral tryptophan derivatives using Negishi cross-coupling reaction of serine-derived iodoalanine with 3-haloindole is described. The best result was obtained when the reaction of N-tosyl-3-bromoindole with N-Cbz-iodoalani