845751-59-9

Basic information

• Product Name: 7-BroMo-2H-indazole
• Synonyms: 7-BroMo-2H-indazole
• CAS NO: 845751-59-9
• Molecular Formula: C₇H₅BrN₂
• Molecular Weight: 197.032
• Mol File: 845751-59-9.mol

Chemical Properties

• Boiling Point: 177.3±23.0 °C(Predicted)
• Appearance: /
• Density: 1.770±0.06 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 12.82±0.30(Predicted)
• CAS DataBase Reference: 7-BroMo-2H-indazole(CAS DataBase Reference)
• NIST Chemistry Reference: 7-BroMo-2H-indazole(845751-59-9)
• EPA Substance Registry System: 7-BroMo-2H-indazole(845751-59-9)

Safety Data

• Hazardous Substances Data: 845751-59-9(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Research and Development:
7-Bromo-2H-indazole is used as a chemical intermediate for the synthesis of new drug candidates due to its unique structure and potential biological activities.
Used in Anticancer Research:
7-Bromo-2H-indazole is used as a potential anticancer agent, given its observed biological activities that may contribute to the inhibition of cancer cell growth and proliferation.
Used in Antimicrobial Research:
7-Bromo-2H-indazole is used as a potential antimicrobial agent, indicating its possible application in the development of new treatments for infectious diseases.
Used in Medicinal Chemistry Research:
7-Bromo-2H-indazole is used as a building block in the synthesis of novel molecules, facilitating the discovery of new compounds with therapeutic potential.

Upstream product

• 601-87-6 3-methyl-2-nitroaniline 
• 53848-17-2 2-bromo-6-methylaniline 
• 845751-60-2 (2-bromo-6-methylphenyl)[(1,1-dimethylethyl)thio]diazene 
• 52414-97-8 1-bromo-3-methyl-2-nitro-benzene 

Downstream Products

• 701910-14-7 7-bromo-2-methyl-2H-indazole 
• 1000576-59-9 7-bromo-1-methyl-1H-indazole 
• 845751-61-3 7-(2,4-dichloro-phenyl)-1H-indazole 
• 845751-92-0 C₈H₆BrClN₂O₂S 
• 701910-21-6 7-(2,4-dichloro-phenyl)-2-methyl-2H-indazol-3-ylamine 
• 701910-15-8 7-(2,4-dichloro-phenyl)-2-methyl-2H-indazole 

Relevant articles and documents

Design and Synthesis of a Novel Series of Bicyclic Heterocycles As Potent γ-Secretase Modulators

The design and the synthesis of several chemical subclasses of imidazole containing γ-secretase modulators (GSMs) is described. Conformational restriction of pyridone 4 into bicyclic pyridone isosteres has led to compounds with high in vitro and in vivo p

GABANERGIC MODULATORS

This invention relates to the use of compounds of benzoindazole derivatives salts and solvates thereof for the preparation of a medicament for modulating alpha2 subtype GABA A receptors. The invention further relates to novel heterocyclic compounds and pharmaceutical compositions containing said compounds. In addition the invention relates to the use of compounds of formula (I) salts and solvates thereof for the preparation of a medicament for the treatment of depression, an anxiety disorder, a psychiatric disorder, a learning or cognitive disorder, a sleep disorder, a convulsive or seizure disorder or pain.

Indazole derivatives as CRF antagonists

This invention relates to compounds which are generally CRF-1 receptor antagonists and which are represented by Formula I or Formula II: wherein R3 is optionally substituted aryl or heteroaryl, R1 and R2 are as defined in