926307-72-4

Basic information

• Product Name: 1H-Isoindole-5-carboxylic acid, 2,3-dihydro-1-oxo-, Methyl ester
• Synonyms: 1H-Isoindole-5-carboxylic acid, 2,3-dihydro-1-oxo-, Methyl ester;Methyl 1-oxo-2,3-dihydro-1H-isoindole-5-carboxylate;Methyl 1-oxoisoindoline-5-carboxylate;1-Oxo-2,3-dihydro-1H-isoindole-5-carboxylic acid methyl ester
• CAS NO: 926307-72-4
• Molecular Formula: C₁₀H₉NO₃
• Molecular Weight: 191.18336
• Mol File: 926307-72-4.mol

Chemical Properties

• Appearance: /
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 1H-Isoindole-5-carboxylic acid, 2,3-dihydro-1-oxo-, Methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Isoindole-5-carboxylic acid, 2,3-dihydro-1-oxo-, Methyl ester(926307-72-4)
• EPA Substance Registry System: 1H-Isoindole-5-carboxylic acid, 2,3-dihydro-1-oxo-, Methyl ester(926307-72-4)

Safety Data

• Hazardous Substances Data: 926307-72-4(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Research and Development:
1H-Isoindole-5-carboxylic acid, 2,3-dihydro-1-oxo-, methyl ester is used as a synthetic intermediate for the creation of new drugs and medications. Its unique structure and reactivity make it a valuable component in the design and synthesis of pharmaceutical compounds, potentially leading to advancements in various therapeutic areas.
Used in Organic Synthesis:
In the field of organic synthesis, 1H-Isoindole-5-carboxylic acid, 2,3-dihydro-1-oxo-, methyl ester is utilized as a versatile building block. Its chemical properties allow it to be incorporated into a wide range of organic compounds and derivatives, contributing to the development of novel chemical entities with diverse applications.
Used in Agricultural Chemicals:
1H-Isoindole-5-carboxylic acid, 2,3-dihydro-1-oxo-, methyl ester may also find applications in the agricultural sector, potentially serving as a component in the development of new pesticides, herbicides, or other agrochemicals. Its chemical structure could offer unique modes of action or enhanced efficacy in these applications.
Used in Materials Science:
1H-Isoindole-5-carboxylic acid, 2,3-dihydro-1-oxo-, methyl ester's potential use in materials science is suggested by its chemical properties and reactivities. It could be employed in the synthesis of new materials with specific properties, such as improved stability, reactivity, or other characteristics that are valuable in various industrial applications.

Upstream product

• 67-56-1 methanol 
• 552330-86-6 5-bromoisoindolin-1-one 
• 201230-82-2 carbon monoxide 
• 78471-43-9 methyl 4-bromo-2-(bromomethyl)benzoate 
• 5372-81-6 dimethyl aminoterephthalate 
• 58331-98-9 dimethyl 2-cyanoterephthalate 
• 99548-55-7 4-bromo-2-methyl-benzoic acid methyl ester 
• 3375-31-3 palladium diacetate 

Downstream Products

• 1421922-95-3 5-acetyl-2,3-dihydro-1H-isoindol-1-one 
• 926307-97-3 5-(hydroxymethyl)isoindolin-1-one 
• 23386-40-5 1-oxo-2,3-dihydro-1H-isoindole-5-carboxylic acid 

Relevant articles and documents

Degradable hydrogel under physiological conditions

The present invention discloses a hydrogel that can be degraded under physiological conditions. The hydrogel includes at least one backbone moiety and an optional crosslinking moiety, and biodegradable linkers connecting backbone moieties and crosslinking moieties can be degraded by intramolecular cyclization.

NOVEL CLOSTRIDIUM DIFFICILE TOXIN INHIBITORS

The present invention relates to benzodiazepine derivative compounds of formula (I), or pharmaceutically acceptable salts thereof. The present benzodiazepine compounds are useful Clostridium difficile inhibitors in the treatment of Clostridium difficile infection in humans. The present invention provides a pharmaceutical composition containing benzodiazepine compounds of formula (I) and a method of making as well as a method of using the same in treating patients infected with Clostridium difficile infection by administering the same. The compounds of the present invention may be used in combination with additional antibiotics or anti-toxin antibody drugs.

BIOREVERSABLE PROMOIETIES FOR NITROGEN-CONTAINING AND HYDROXYL-CONTAINING DRUGS

Disclosed are promoieties of the following formula which can be used to form prodrugs of nitrogen-containing or hydroxyl-containing drug or a pharmaceutically active agent: (I) and pharmaceutical compositions comprising the prodrugs.

TRPM8 ANTAGONISTS AND THEIR USE IN TREATMENTS

Compounds of Formula (I) are useful as antagonists of TRPM8. Such compounds are useful in treating a number of TRPM8 mediated disorders and conditions and may be used to prepare medicaments and pharmaceutical compositions useful for treating such disorders and conditions. Examples of such disorders include, but are not limited to, migraines and neuropathic pain. Compounds of Formula (I) have a structure where the definitions of the variables are provided herein.