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2,6-dibromo-4-methoxyaniline, also known as 2,6-dibromo-4-methoxybenzenamine, is a chemical compound with the molecular formula C7H7Br2NO. It is a substituted aniline derivative characterized by the presence of two bromine atoms and one methoxy group attached to the benzene ring. This pale yellow to brown solid is sparingly soluble in water but more soluble in organic solvents. Recognized for its antimicrobial and antioxidant properties, it is also considered a hazardous substance, necessitating careful handling and disposal according to safety protocols.

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  • 95970-05-1 Structure
  • Basic information

    1. Product Name: 2,6-dibromo-4-methoxyaniline
    2. Synonyms: 2,6-dibromo-4-methoxyaniline;2,6-Dibromo-p-anisidine;6-dibroMo-4-MethoxybenzenaMine;2,6-DibroMo-4-Methoxy-phenylaMine;2,6-dibroMo-4-MethoxybenzenaMine;Benzenamine, 2,6-dibromo-4-methoxy-
    3. CAS NO:95970-05-1
    4. Molecular Formula: C7H7Br2NO
    5. Molecular Weight: 281
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 95970-05-1.mol
  • Chemical Properties

    1. Melting Point: 81-83℃
    2. Boiling Point: 293.6°C at 760 mmHg
    3. Flash Point: 131.4°C
    4. Appearance: /
    5. Density: 1.897
    6. Vapor Pressure: 0.00171mmHg at 25°C
    7. Refractive Index: 1.627
    8. Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
    9. Solubility: N/A
    10. CAS DataBase Reference: 2,6-dibromo-4-methoxyaniline(CAS DataBase Reference)
    11. NIST Chemistry Reference: 2,6-dibromo-4-methoxyaniline(95970-05-1)
    12. EPA Substance Registry System: 2,6-dibromo-4-methoxyaniline(95970-05-1)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 95970-05-1(Hazardous Substances Data)

95970-05-1 Usage

Uses

Used in Pharmaceutical Industry:
2,6-dibromo-4-methoxyaniline serves as an intermediate in the synthesis of various pharmaceuticals, leveraging its chemical structure to contribute to the development of new medications.
Used in Dye Industry:
In the dye industry, 2,6-dibromo-4-methoxyaniline is utilized for the production of dyes, capitalizing on its chemical properties to create a range of colorants for different applications.
Used in Agrochemical Industry:
2,6-dibromo-4-methoxyaniline is employed in the agrochemical sector, where it plays a role in the synthesis of compounds used in agricultural chemicals, potentially enhancing crop protection and yield.
Used for Antimicrobial Purposes:
Due to its antimicrobial properties, 2,6-dibromo-4-methoxyaniline can be used in applications requiring the inhibition of microbial growth, contributing to the preservation and safety of various products.
Used for Antioxidant Applications:
The antioxidant characteristics of 2,6-dibromo-4-methoxyaniline make it suitable for use in applications where protection against oxidation is necessary, such as in the stabilization of certain chemical processes or materials.

Check Digit Verification of cas no

The CAS Registry Mumber 95970-05-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,5,9,7 and 0 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 95970-05:
(7*9)+(6*5)+(5*9)+(4*7)+(3*0)+(2*0)+(1*5)=171
171 % 10 = 1
So 95970-05-1 is a valid CAS Registry Number.
InChI:InChI=1/C7H7Br2NO/c1-11-4-2-5(8)7(10)6(9)3-4/h2-3H,10H2,1H3

95970-05-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 2,6-Dibromo-4-methoxyaniline

1.2 Other means of identification

Product number -
Other names 2,6-dibromo-4-methoxyphenylamine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:95970-05-1 SDS

95970-05-1Relevant articles and documents

From Zn(II) to Cu(II) framework via single-crystal to single-crystal metathesis with superior gas uptake and heterogeneous catalytic properties

Gupta, Mayank,De, Dinesh,Tomar, Kapil,Bharadwaj, Parimal K.

, p. 925 - 934 (2018/08/06)

In this work, a Zn(II) framework, {[Zn2(L)4(H2O)4]·(7DMF)(7H2O)}n (1Zn), has been synthesized using a bent tetracarboxylic acid ligand (H4L). The structure of 1Zn contains [Zn2(COO)4] paddle-wheel secondary building units with axial sites occupied by water molecules. Interestingly, the isostructural Cu(II) framework {[Cu2(L)4(H2O)4]·(7DMF)(7H2O)}n (1Cu) has been obtained via single-crystal to single-crystal metathesis reaction. The activated 1Cu (denoted as a1Cu; a stands for activated) has open coordination sites. This species showed enhanced CO2 adsorption and heterogeneous catalytic properties for the Hantzsch coupling reaction involving condensation of an aldehyde with ethyl acetoacetate and ammonium acetate to produce 1,4-dihydropyridines, and three-component coupling of amines, aldehydes and alkynes to generate propargylic amines with high efficiency.

Synthesis of Indole-, Benzo[ b]thiophene-, and Benzo[ b]selenophene-Based Analogues of the Resveratrol Dimers Viniferifuran and (±)-Dehydroampelopsin B

Krzyzanowski, Adrian,Saleeb, Michael,Elofsson, Mikael

supporting information, p. 6650 - 6654 (2018/10/25)

A convenient synthetic strategy to obtain viniferifuran and (±)-dehydroampelopsin B analogues based on the heterocyclic cores of indole, benzo[b]thiophene, and benzo[b]selenophene is presented. The key transformations utilized in the described syntheses include Sonogashira couplings, Cacchi and alkyne electrophilic cyclizations, Horner-Wadsworth-Emmons (HWE) reaction, chemoselective Suzuki-Miyaura couplings, and acid-promoted intramolecular cyclization to form the seven-membered ring of (±)-dehydroampelopsin B.

Multi-responsive metal-organic lantern cages in solution

Brega, Valentina,Zeller, Matthias,He, Yufan,Peter Lu,Klosterman, Jeremy K.

supporting information, p. 5077 - 5080 (2015/03/30)

Soluble copper-based M4L4 lantern-type metal-organic cages bearing internal amines were synthesized. The solution state integrity of the paramagnetic metal-organic cages was demonstrated using NMR, DLS, MS, and AFM spectroscopy. 1D s

Enantioposition-selective copper-catalyzed azide-alkyne cycloaddition for construction of chiral biaryl derivatives

Osako, Takao,Uozumi, Yasuhiro

supporting information, p. 5866 - 5869 (2015/01/08)

A highly enantioposition-selective copper-catalyzed azide-alkyne cycloaddition (CuAAC) of dialkynes bearing prochiral biaryls has been developed for the construction of 1,2,3-triazoles bearing axially chiral biaryl groups in up to 76% yield and up to 99% ee.

Convergent total syntheses of the amaryllidaceae alkaloids lycoranine A, lycoranine B, and 2-methoxypratosine

Kim, Hye Sun,Banwell, Martin G.,Willis, Anthony C.

, p. 5103 - 5109 (2013/07/05)

The title alkaloids, 1, 2, and 3 respectively, have been prepared in a convergent manner by two related routes. The superior one involves C-H functionalization of the relevant 5-methoxyindole at C-7 using Hartwig's protocol and thus forming the correspond

Molecular spoked wheels: Synthesis and self-assembly studies on rigid nanoscale 2D objects

Aggarwal, A. Vikas,Jester, Stefan-S.,Taheri, Sara Mehdizadeh,Foerster, Stephan,Hoeger, Sigurd

supporting information, p. 4480 - 4495 (2013/05/23)

We present the efficient synthesis of a new molecular spoked-wheel structure (MSW-3). Two derivatives with diameters of approximately 4 nm have been prepared. By highlighting the importance of pseudo-high-dilution conditions during cyclization, we were able to access the compounds on a several hundred milligram scale. In addition to the standard characterization (NMR spectroscopy, MS), we describe a detailed investigation of the optical properties of the fluorescent MSWs by comparison with appropriate model chromophores. Furthermore, a comprehensive study of the structure in solution by means of light- and X-ray scattering experiments has been conducted. Scanning tunneling microscopy (STM) revealed the two-dimensional organization of the molecules on highly oriented pyrolytic graphite and emphasized the spoked-wheel structure. The diameter of these molecules measured by small-angle X-ray scattering is in very good agreement with that obtained from STM and matches the results of molecular modeling. This confirms the rigidifying effect of the spokes, which results in highly shape-persistent nanometer-sized oblate organic compounds. Copyright

Catalytic asymmetric pictet-spengler-type reaction for the synthesis of optically active indolo[3,4-cd][1]benzazepines

Cheng, Dao-Juan,Wu, Hai-Bian,Tian, Shi-Kai

supporting information; experimental part, p. 5636 - 5639 (2011/12/02)

A new strategy has been introduced to develop a catalytic asymmetric Pictet-Spengler-type reaction by replacing the aldehyde with an imine. A range of 4-(2-aminoaryl)indoles smoothly undergo the chiral phosphoric acid catalyzed asymmetric Pictet-Spengler-

NOVEL AMINO AZAHETEROCYCLIC CARBOXAMIDES

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Page/Page column 215-216, (2010/09/03)

The invention provides novel substituted amino azaheterocyclic carboxamide compounds according to Formula (I), their manufacture and use for the treatment of hyperproliferative diseases, such as cancer.

17BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 INHIBITORS FOR THE TREATMENT OF HORMONE-RELATED DISEASES

-

Page/Page column 12-13, (2010/08/18)

The invention relates to the use of non-steroidal 17beta-hydroxysteroid dehydrogenase type 1 inhibitors for the treatment and prophylaxis of hormone-dependent, particularly estrogen-dependent, diseases.The invention further relates to suitable inhibitors and to a method for the production thereof.

2D networks of rhombic-shaped fused dehydrobenzo[12]annulenes: Structural variations under concentration control

Tahara, Kazukuni,Okuhata, Satoshi,Adisoejoso, Jinne,Lei, Shengbin,Fujita, Takumi,De Feyter, Steven,Tobe, Yoshito

supporting information; experimental part, p. 17583 - 17590 (2010/04/01)

A series of alkyl- and alkoxy-substituted rhombic-shaped bisDBA derivatives 1a-d, 2a, and 2b were synthesized for the purpose of the formation of porous networks at the 1,2,4-trichlorobenzene (TCB)/graphite interface. Depending on the alkyl-chain length and the solute concentration, bisDBAs exhibit five network structures, three porous structures (porous A, B, and C), and two nonporous structures (nonporous D and E), which are attributed to their rhombic core shape and the position of the substituents. BisDBAs 1a and 1b with the shorter alkyl chains favorably form a porous structure, whereas bisDBAs 1c and 1d with the longer alkyl chains are prone to form nonporous structures. However, upon dilution, nonporous structures are typically transformed into porous ones, a trend that can be understood by the effect of surface coverage, molecular density, and intermolecular interactions on the system's enthalpy. Furthermore, porous structures are stabilized by the coadsorption of solvent molecules. The most intriguing porous structure, the Kagome pattern, was formed for all compounds at least to some extent, and the size of its triangular and hexagonal pores could be tuned by the alkyl-chain length. The present study proves that the concentration control is a powerful and general tool for the construction of porous networks at the liquid-solid interface.

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