10570-46-4

Basic information

• Product Name: Phosphonic acid, (4-chlorobenzoyl)-, diethyl ester
• CAS NO: 10570-46-4
• Molecular Formula: C11H14ClO4P
• Molecular Weight: 276.657
• Mol File: 10570-46-4.mol
• Article Data: 19

Chemical Properties

• CAS DataBase Reference: Phosphonic acid, (4-chlorobenzoyl)-, diethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Phosphonic acid, (4-chlorobenzoyl)-, diethyl ester(10570-46-4)
• EPA Substance Registry System: Phosphonic acid, (4-chlorobenzoyl)-, diethyl ester(10570-46-4)

Safety Data

• Hazardous Substances Data: 10570-46-4(Hazardous Substances Data)

Upstream product

• 52057-50-8 α-trimethylsiloxy-p-chlorobenzylphosphonic acid diethyl ester 
• 104-88-1 4-chlorobenzaldehyde 
• 108054-54-2 diethyl (4-chlorophenyl)(hydroxy)methylphosphonate 
• 122-01-0 4-chloro-benzoyl chloride 
• 122-52-1 triethyl phosphite 
• 78-40-0 triethyl phosphate 
• 3226-37-7 4-chlorophenyl thiocyanate 
• 762-04-9 phosphonic acid diethyl ester 
• 106-39-8 bromochlorobenzene 
• 201230-82-2 carbon monoxide 
• 110480-88-1 diethyl 1-amino(p-chlorophenyl)methylphosphonate 

Downstream Products

• 16656-47-6 diethyl [N-(hydroxy)imino](p-chlorophenyl)methylphosphonate 
• 27594-52-1 diethyl (p-chlorophenyl)carbamothioylphosphonate 
• 2617-79-0 N-(4-chlorophenyl)formamide 
• 27594-54-3 diethyl p-chlorobenzoylphosphoramidate 
• 74-11-3 para-chlorobenzoic acid 
• 256511-59-8 diethyl 1-(p-chlorobenzoyloxy)octylphosphonate 
• 1609483-70-6 1-(4-chlorophenyl)-2-methyl-4-phenylbutan-1-one 
• 1602490-09-4 diethyl (S)-(4-chlorophenyl)(hydroxy)[(2R)-5-oxo-2,5-dihydrofuran-2-yl]methylphosphonate 
• 1513846-36-0 diethyl ((2S,3S)-2-(4-chlorophenyl)-5-oxo-3-phenyltetrahydrofuran-2-yl)phosphonate 
• 1402349-73-8 (S)-diethyl (4-chlorophenyl)cyano(hydroxy)methylphosphonate 
• 1402349-94-3 C₁₅H₂₃ClNO₄PSi 

Relevant articles and documents

Preparation of α-ketophosphonates by oxidation of α-hydroxyphosphonates with Pyridinium Chlorochromate (PCC)

Various types of diethyl α-hydroxyphosphonates were converted efficiently to their corresponding diethyl α-ketophosphonates by pyridiinum chlorochromate (PCC) without cleavage of C(O) - P bond in the absence of solvent or in solution in high yields.

Surface-mediated solid-phase reactions: The preparation of acyl phosphonates by oxidation of 1-hydroxyphosphonates on the solid surface

Alumina-supported CrO3, under solvent-free conditions, was found to be an efficient oxidizing reagent for the preparation of acyl phosphonates from 1-hydroxyphosphonates. This method is an easy, rapid, and high-yielding reaction for the prepara

Enantioselective vinylogous aldol reaction of acylphosphonates with 3-alkylidene oxindoles

A simple strategy for yielding chiral tertiary α-hydroxy phosphonates that integrates two highly biologically relevant scaffolds namely 3-alkylidene-2-oxindoles and phosphonates has been described. The hydrogen bonding ability of the bifunctional thiourea catalyst allows simultaneous dual activation of a vinylogous oxindole nucleophile and an acylphosphonate electrophile, affording hydroxyphosphonato-3-alkylidene-2-oxindoles as aldol adducts in high yields (up to 92%) with excellent stereocontrol (up to 99% ee).

Visible photocatalysis of novel oxime phosphonates: Synthesis of β-aminophosphonates

A novel type of oxime phosphonate was synthesized and used in the intermolecular cascade radical addition reaction of alkenes to access β-aminophosphonates via visible-light-driven N-centered iminyl radical-mediated and redox-neutral selective C-P single-bond cleavage in an active phosphorus radical route. The procedure is characterized by its ability to achieve the construction of Csp3-P and Csp3-N bonds without the requirement for oxidants and bases.