113211-94-2 Usage
Description
2,3-Difluorobenzyl bromide is an organic compound characterized by the presence of two fluorine atoms at the 2nd and 3rd positions of a benzyl bromide structure. It is a clear colorless to light yellow liquid and is known for its chemical reactivity and stability.
Uses
Used in Pharmaceutical Industry:
2,3-Difluorobenzyl bromide is used as a synthetic intermediate for the development of chemokine antagonists, which are crucial in the treatment of various diseases, including autoimmune disorders and inflammatory conditions. Its unique structure allows for the creation of novel compounds with potential therapeutic applications.
Used in Chemical Synthesis:
2,3-Difluorobenzyl bromide serves as a valuable building block in the synthesis of various organic compounds, particularly those with fluorinated aromatic rings. Its reactivity and stability make it a preferred choice for researchers and chemists working on the development of new molecules with specific properties and applications.
Check Digit Verification of cas no
The CAS Registry Mumber 113211-94-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,3,2,1 and 1 respectively; the second part has 2 digits, 9 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 113211-94:
(8*1)+(7*1)+(6*3)+(5*2)+(4*1)+(3*1)+(2*9)+(1*4)=72
72 % 10 = 2
So 113211-94-2 is a valid CAS Registry Number.
InChI:InChI=1/C4F7I/c5-1(2(6)12)3(7,8)4(9,10)11/b2-1-
113211-94-2Relevant articles and documents
NOVEL INHIBITORS
-
Page/Page column 88; 170, (2014/09/29)
The invention relates to a compound of formula (I) or a pharmaceutically acceptable salt, solvate or polymorph thereof, including all tautomers and stereoisomers thereof, wherein R1, R2, R3, R4 and R5 are as defined herein, as inhibitors of glutaminyl cyclase (QC, EC 2.3.2.5). QC catalyzes the intramolecular cyclization of N- terminal glutamine residues into pyroglutamic acid (5-oxo-prolyl, pGlu*) under liberation of ammonia and the intramolecular cyclization of N-terminal glutamate residues into pyroglutamic acid under liberation of water.