1135-72-4

Basic information

• Product Name: 1-(hydroxy-phenyl-methyl)cyclohexan-1-ol
• Synonyms: 1-(hydroxy-phenyl-methyl)cyclohexan-1-ol
• CAS NO: 1135-72-4
• Molecular Formula: C₁₃H₁₈O₂
• Molecular Weight: 0
• Mol File: 1135-72-4.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 350.8°Cat760mmHg
• Flash Point: 167.1°C
• Appearance: /
• Density: 1.156g/cm³
• Vapor Pressure: 1.6E-05mmHg at 25°C
• Refractive Index: 1.585
• CAS DataBase Reference: 1-(hydroxy-phenyl-methyl)cyclohexan-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(hydroxy-phenyl-methyl)cyclohexan-1-ol(1135-72-4)
• EPA Substance Registry System: 1-(hydroxy-phenyl-methyl)cyclohexan-1-ol(1135-72-4)

Safety Data

• Hazardous Substances Data: 1135-72-4(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Tetrahedron Letters, 34, p. 2311, 1993 DOI: 10.1016/S0040-4039(00)77601-5

InChI:InChI=1/C13H18O2/c14-12(11-7-3-1-4-8-11)13(15)9-5-2-6-10-13/h1,3-4,7-8,12,14-15H,2,5-6,9-10H2

Upstream product

• 947-19-3 1-hydroxycyclohexyl phenyl ketone 
• 412346-08-8 8,16-diphenyl-7,15-dioxa-dispiro[5.2.5.2]hexadecane-8,16-diol 
• 1195776-87-4 1-(methoxymethoxyphenyl)methylcyclohexanol 
• 34877-64-0 2-phenyl-1-oxaspiro[2,5]octane 
• 1135-71-3 (1-chlorocyclohexyl)(phenyl)methanone 
• 712-50-5 Cyclohexyl phenyl ketone 
• 4714-09-4 1-benzylcyclohexene 
• 1944-01-0 1-benzylcyclohexan-1-ol 
• 4410-75-7 (cyclohexylmethyl)benzene 
• 108-94-1 cyclohexanone 
• 100-52-7 benzaldehyde 

Downstream Products

• 947-19-3 1-hydroxycyclohexyl phenyl ketone 
• 65-85-0 benzoic acid 

Relevant articles and documents

Oxidative carbon-carbon bond cleavage of 1,2-diols to carboxylic acids/ketones by an inorganic-ligand supported iron catalyst

The carbon-carbon bond cleavage of 1,2-diols is an important chemical transformation. Although traditional stoichiometric and catalytic oxidation methods have been widely used for this transformation, an efficient and valuable method should be further explored from the views of reusable catalysts, less waste, and convenient procedures. Herein an inorganic-ligand supported iron catalyst (NH4)3[FeMo6O18(OH)6]·7H2O was described as a heterogeneous molecular catalyst in acetic acid for this transformation in which hydrogen peroxide was used as the terminal oxidant. Under the optimized reaction conditions, carbon-carbon bond cleavage of 1,2-diols could be achieved in almost all cases and carboxylic acids or ketones could be afforded with a high conversion rate and high selectivity. Furthermore, the catalytic system was used efficiently to degrade renewable biomass oleic acid. Mechanistic insights based on the observation of the possible intermediates and control experiments are presented.

Direct metalation of methoxymethyl arylmethyl ethers: A tin-free approach to the generation of α-alkoxyalkoxy-substituted aryllithiums

The generation of a series of α-methoxymethoxy-substituted arylmethyllithiums was achieved by direct metalation of the corresponding arylmethyl methoxymethyl ethers. While the effect of substituents at the benzylic position is straightforward, substituent

Samarium Dibromide, an Efficient Reagent for the Pinacol Coupling Reactions.

The preparation of SmBr2 from Sm2O3 is described.This samarium (II) compound is a powerful one electron reductant able to very efficiently mediate pinacolic couplings.Cross couplings are effective in some cases, for example a chiral diol can be obtained from benzophenone and camphor.Intramolecular pinacolization of a diketone has been performed.