1944-01-0Relevant articles and documents
Naphthalene-Catalysed Reductive Desulfonylation with Lithium: Alkyllithiums from Alkyl Phenyl Sulfones
Guijaro, David,Yus, Miguel
, p. 2965 - 2968 (1994)
The reaction of alkyl aryl sulfones 1 with an excess of lithium powder and a catalytic amount of naphthalene (8 mol percent) in the presence of a carbonyl compound iCHO, PhCHO, Et2CO, (CH2)5CO> or trimethylchlorosilane (Barbier-type conditions) in THF at temperatures ranging between -78 and 20 deg C leads, after hydrolysis with water, to the expected coupling products, arising from the corresponding alkyllithium in situ generated, in 30-61percent yields.
Triphosgene and DMAP as Mild Reagents for Chemoselective Dehydration of Tertiary Alcohols
Ganiu, Moshood O.,Cleveland, Alexander H.,Paul, Jarrod L.,Kartika, Rendy
supporting information, p. 5611 - 5615 (2019/08/01)
The utility of triphosgene and DMAP as mild reagents for chemoselective dehydration of tertiary alcohols is reported. Performed in dichloromethane at room temperature, this reaction is readily tolerated by a broad scope of substrates, yielding alkenes preferentially with the (E)-geometry. While formation of the Hofmann products is generally favored, a dramatic change in alkene selectivity toward the Zaitzev products is observed when the reaction is carried out in dichloroethane at reflux.
PROCESS FOR PREPARING ARYL KETONE
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Paragraph 0160; 0161, (2017/06/12)
A process for preparing aryl ketones is disclosed. The process includes photo-oxidizing a compound of formula (V), (VI), (VII) or (VIII): in the presence of an oxidative system comprising at least one bromide compound to form aryl ketones. X1, X2, R1, R2, R3, L1, L2, L3, L4, t, n, m and p have the meanings as described in the specification and claims.