129306-17-8

Basic information

• Product Name: 4,7-Diazaspiro[2.5]octane-5,8-dione
• Synonyms: 4,7-Diazaspiro[2.5]octane-5,8-dione
• CAS NO: 129306-17-8
• Molecular Formula: C6H8N2O2
• Molecular Weight: 140.13992
• Mol File: 129306-17-8.mol

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 4,7-Diazaspiro[2.5]octane-5,8-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 4,7-Diazaspiro[2.5]octane-5,8-dione(129306-17-8)
• EPA Substance Registry System: 4,7-Diazaspiro[2.5]octane-5,8-dione(129306-17-8)

Safety Data

• Hazardous Substances Data: 129306-17-8(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
4,7-Diazaspiro[2.5]octane-5,8-dione is used as a potential therapeutic agent for its pharmacological properties. Its unique structure and potential biological activities make it a promising candidate for further research and development in the field of medicine.
Used in Organic Synthesis:
4,7-Diazaspiro[2.5]octane-5,8-dione is used as a key intermediate in the synthesis of various organic compounds. Its unique spirocyclic structure allows for the creation of novel molecules with potential applications in different industries.
Used in Medicinal Chemistry:
4,7-Diazaspiro[2.5]octane-5,8-dione is used as a building block in the design and synthesis of new pharmaceutical compounds. Its potential biological activities and unique structure make it a valuable tool for medicinal chemists in the development of innovative drugs.
Further research is needed to fully understand the chemical and pharmacological properties of 4,7-Diazaspiro[2.5]octane-5,8-dione, which will help in exploring its potential applications in various fields.

Upstream product

• 1012781-78-0 C₇H₁₂N₂O₃ 
• 5680-79-5 glycine ethyl ester hydrochloride 
• 84677-06-5 (benzyloxycarbonylamino)cyclopropanecarboxylic acid 
• 145122-59-4 [(1-benzyloxycarbonylaminocyclopropanecarbonyl)amino]acetic acid ethyl ester 
• 191033-44-0 1-(2-Benzyloxycarbonylamino-acetylamino)-cyclopropanecarboxylic acid methyl ester 
• 140195-93-3 1-(2-Benzyloxycarbonylamino-acetylamino)-cyclopropanecarboxylic acid ethyl ester 
• 129306-16-7 [(1-Amino-cyclopropanecarbonyl)-amino]-acetic acid ethyl ester 

Downstream Products

• 99214-52-5 4,7-diazaspiro[2.5]octane 
• 145256-97-9 1-(2,4-difluorophenyl)-6-fluoro-7-(4,7-diazaspiro<2,5>octan-7-yl)-1,4-dihydro-4-oxo<1,8>naphthyridine-3-carboxylic acid trifluoroacetic acid salt 
• 145122-69-6 ethyl 1-(2,4-difluorophenyl)-6-fluoro-7-(4,7-diazaspiro<2,5>octan-7-yl)-1,4-dihydro-4-oxo<1,8>naphthyridine-3-carboxylate 
• 145122-56-1 4,7-diazaspiro<2,5>octane dihydrochloride 

Relevant articles and documents

A 4, 7 - diaza spiro [2.5] octane -7 - formic acid tert-butyl synthetic method

The invention belongs to the technical field of chemical synthesis of N-heterocycle-containing drug intermediates, and particularly relates to a synthesis method of tert-butyl 4,7-diazaspiro[2.5]octyl-7-formate. By using diethyl malonate as a raw material, cyclization reaction, Hofmann reaction, hydrolysis reaction, acylation reaction for recyclization, reduction reaction and the like are performed to conveniently synthesize the target compound product. The method has the advantages of simple synthesis technique, cheap and accessible raw materials, mild reaction conditions, high controllability, low cost and high yield, and is convenient to operate.

SUBSTITUTED NICOTINAMIDE COMPOUNDS

The present invention relates to a novel class of substituted nicotinamides. These compounds can inhibit histone deacetylase and are suitable for use in selectively inducing terminal differentiation, and arresting cell growth and/or apoptosis of neoplasti

An unexpected aminocyclopropane reductive rearrangement

A reductive rearrangement of aminocyclopropanes is described for the synthesis of cis- or trans-fused bicyclic 1,2-diaminocyclobutanes. Ionization of a cyclic aminal using BF3·OEt2 induces rearrangement to a cyclobutyl iminium ion, w

SUBSTITUTED NICOTINAMIDE COMPOUNDS

The present invention relates to a novel class of substituted nicotinamides.. These compounds can inhibit histone deacetylase and are suitable for use in selectively inducing terminal differentiation, and arresting cell growth and/or apoptosis of neoplast

FIVE-MEMBERED HETEROCYCLIC DERIVATIVE

The present invention relates to a compound represented by formula (I): a salt of the compound, or a solvate of the compound or the salt; a drug containing any of the compounds, the salts, and the solvates; a preventive and/or therapeutic agent for an ischemic disease containing any of the compounds, the salts, and the solvates; and a platelet coagulation inhibitor containing any of the compounds, the salts, and the solvates. The compound of the present invention is useful as a strong platelet coagulation inhibitor without inhibiting COX-1 or COX-2.

Cyclic dipeptides with 1-aminocyclopropane-1-carboxylic acid

Cyclic dipeptides of the formula cyclo(-Acc-X-), where Acc = 1-aminocyclopropane-1-carboxylic acid, X = Gly, Ala, Val, Leu, Phe or Tyr, were synthesized. The prepared 2,5-piperazinediones showed no proliferative or antiproliferative activity on normal hum

Spiro compound

The present invention relates to spiro compounds of general formula I: STR1 wherein the substituents are herein below defined. The present invention relates to antibacterial spiro compounds which are of value as drugs for humans, veterinary drugs or drugs for use in fish culture or as preservatives, and to antibacterial compositions containing one or more of the same compounds as active ingredients.