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Cas Database

13130-19-3

13130-19-3

Identification

  • Product Name:Dibenzofuran,1,2,3,4-tetrahydro-

  • CAS Number: 13130-19-3

  • EINECS:

  • Molecular Weight:172.227

  • Molecular Formula: C12H12 O

  • HS Code:2932999099

  • Mol File:13130-19-3.mol

Synonyms:1,2,3,4-Tetrahydrodibenzofuran

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Safety information and MSDS view more

  • Signal Word:no data available

  • Hazard Statement:no data available

  • First-aid measures: General adviceConsult a physician. Show this safety data sheet to the doctor in attendance.If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician. In case of skin contact Wash off with soap and plenty of water. Consult a physician. In case of eye contact Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician. If swallowed Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.

  • Fire-fighting measures: Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide. Wear self-contained breathing apparatus for firefighting if necessary.

  • Accidental release measures: Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. For personal protection see section 8. Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided. Pick up and arrange disposal. Sweep up and shovel. Keep in suitable, closed containers for disposal.

  • Handling and storage: Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Avoid exposure - obtain special instructions before use.Provide appropriate exhaust ventilation at places where dust is formed. For precautions see section 2.2. Store in cool place. Keep container tightly closed in a dry and well-ventilated place.

  • Exposure controls/personal protection:Occupational Exposure limit valuesBiological limit values Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday. Eye/face protection Safety glasses with side-shields conforming to EN166. Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Skin protection Wear impervious clothing. The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique(without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it. Respiratory protection Wear dust mask when handling large quantities. Thermal hazards

Supplier and reference price

  • Manufacture/Brand
  • Product Description
  • Packaging
  • Price
  • Delivery
  • Purchase
  • Manufacture/Brand:AccelPharmtech
  • Product Description:1,2,3,4-tetrahydro-Dibenzofuran 97.00%
  • Packaging:5G
  • Price:$ 3230
  • Delivery:In stock
  • Buy Now
  • Manufacture/Brand:AccelPharmtech
  • Product Description:1,2,3,4-tetrahydro-Dibenzofuran 97.00%
  • Packaging:1G
  • Price:$ 1890
  • Delivery:In stock
  • Buy Now

Relevant articles and documentsAll total 35 Articles be found

Copper-catalysed benzofuran synthesis: developing aryl bromide-alkenyl triflates as general heterocycle precursors

Tadd, Andrew C.,Fielding, Mark R.,Willis, Michael C.

, p. 7578 - 7581 (2007)

A range of conjugated aryl bromide-alkenyl triflates, previously described as indole precursors, are efficiently converted to the corresponding benzofurans when treated with CuI/TMEDA and potassium hydroxide.

-

Caubere,P.,Lalloz,L.

, p. 2859 - 2863 (1975)

-

-

Cullinane,Padfield

, p. 1131,1133 (1935)

-

Efficient [3,3]-sigmatropic rearrangement accelerated by a trifluoroacetyl group: Synthesis of benzofurans under mild conditions

Miyata, Okiko,Takeda, Norihiko,Morikami, Yoshiaki,Naito, Takeaki

, p. 254 - 256 (2003)

The [3,3]-sigmatropic rearrangement took place smoothly during the course of trifluoroacetylation of O-phenyl-oxime at below room temperature to give the dihydrobenzofuran or benzofuran as a result of concomitant cyclization.

Supported Pt-Ni bimetallic nanoparticles catalyzed hydrodeoxygenation of dibenzofuran with high selectivity to bicyclohexane

Cai, Chun,Wu, Pengyu

supporting information, (2021/07/10)

Catalytic hydrodeoxygenation (HDO) is one of the most effective methods to upgrade the oxygen-containing compounds derived from coal tar to valuable hydrocarbons. Herein, an efficient bimetallic catalyst Pt1Ni4/MgO was prepared and applied in the HDO of dibenzofuran (DBF). High yield (95%) of the desired product bicyclohexane (BCH) was achieved at 240 °C and 1.2 MPa of H2. Superior catalytic performance could be ascribed to the “relay catalysis” of Pt sites and Ni sites, and the reaction pathway is proposed as well. Scale-up experiment and recyclability test were also performed, which demonstrated the recyclability and promising potential application of Pt1Ni4/MgO.

Synthesis of benzofurans from the cyclodehydration of α-phenoxy ketones mediated by Eaton’s reagent

Ma, Lin,Ma, Zhanwei,Zhang, Min,Zhou, Min

, p. 426 - 436 (2020/03/23)

Cyclodehydration of α-phenoxy ketones promoted by Eaton’s reagent (phosphorus pentoxide–methanesulfonic acid) is used to prepare 3-substituted or 2,3-disubstituted benzofurans with moderate to excellent yields under mild conditions. The method provides a facile access to benzofurans from readily available starting materials such as phenols and α-bromo ketones. The reaction is highly efficient, which is attributed to the good reactivity and fluidity of Eaton’s reagent. The reaction can be applied to prepare naphthofurans, furanocoumarins, benzothiophenes, and benzopyrans.

Direct C-H α-Arylation of Enones with ArI(O2CR)2 Reagents

Sousa E Silva, Felipe Cesar,Van, Nguyen T.,Wengryniuk, Sarah E.

, p. 64 - 69 (2020/01/22)

α-Arylation of α,β-unsaturated ketones constitutes a powerful synthetic transformation. It is most commonly achieved via cross-coupling of α-haloenones, but this stepwise strategy requires prefunctionalized substrates and expensive catalysts. Direct enone C-H α-arylation would offer an atom- and step-economical alternative, but such reports are scarce. Herein we report the metal-free direct C-H arylation of enones mediated by hypervalent iodine reagents. The reaction proceeds via a reductive iodonium Claisen rearrangement of in situ-generated β-pyridinium silyl enol ethers. The aryl groups are derived from ArI(O2CCF3)2 reagents, which are readily accessed from the parent iodoarenes. The reaction is tolerant of a wide range of substitution patterns, and the incorporated arenes maintain the valuable iodine functional handle. Mechanistic investigations implicate arylation via an umpoled "enolonium" species and show that the presence of a β-pyridinium moiety is critical for the desired C-C bond formation.

In order to phenol and α - halo as raw material synthetic benzofuran derivatives (by machine translation)

-

Paragraph 0028; 0029; 0030; 0031, (2019/04/14)

The present invention to provide a phenol and α - halo as raw materials, the role of titanium tetrachloride in the reaction of the next step high-efficient method for preparing benzofuran derivative, namely under protection of inert gas, adding phenol to and [...], then heating and stirring to reflux then adding titanium tetrachloride, finally dropping into the α - halo and [...] mixed solution, after the reaction is completed after the separation and purification to obtain the benzofuran derivatives. The synthesizing method of the invention, raw materials are easy, low cost, mild reaction conditions, the operation is simple and easy to control, less side reaction, after treatment is simple, and the product yield is high, production cost is greatly reduced, with better economic benefits, is suitable for the industrial large-scale production. (by machine translation)

One-step regioselective synthesis of benzofurans from phenols and α-Haloketones

Wang, Bingqiao,Zhang, Qiu,Luo, Juan,Gan, Zongjie,Jiang, Wengao,Tang, Qiang

, (2019/06/21)

Reported here is the direct synthesis of naphthofurans and benzofurans from readily available phenols and α-haloketones promoted by titanium tetrachloride which combines Friedel-Crafts-like alkylation and intramolecular cyclodehydration into one step. This simple protocol allows for the formation of a variety of high value naphthofurans and benzofurans within which a series of cyclic and acyclic groups are readily incorporated. This process demonstrates the advantages of high levels of regioselectivity, broad substrate scope, and moderate to excellent yields.

Process route upstream and downstream products

Process route

dibenzofuran
132-64-9,214827-48-2

dibenzofuran

dodecahydrodibenzofuran
13054-98-3

dodecahydrodibenzofuran

1,2,3,4-tetrahydrodibenzo[b,d]furan
13130-19-3

1,2,3,4-tetrahydrodibenzo[b,d]furan

cyclohexylcyclohexane
92-51-3

cyclohexylcyclohexane

2-cyclohexylcyclohexanol
6531-86-8

2-cyclohexylcyclohexanol

2-cyclohexylphenol
119-42-6

2-cyclohexylphenol

1,2,3,4,4a,9b-hexahydrodibenzo[b,d]furan
13524-79-3,151123-20-5

1,2,3,4,4a,9b-hexahydrodibenzo[b,d]furan

Conditions
Conditions Yield
With hydrogen; In decalin; at 200 ℃; for 3h; under 9000.9 Torr; Temperature; Catalytic behavior; Autoclave;
dibenzofuran
132-64-9,214827-48-2

dibenzofuran

dodecahydrodibenzofuran
13054-98-3

dodecahydrodibenzofuran

1,2,3,4-tetrahydrodibenzo[b,d]furan
13130-19-3

1,2,3,4-tetrahydrodibenzo[b,d]furan

cyclohexylcyclohexane
92-51-3

cyclohexylcyclohexane

d,l-2-cyclohexylcyclohexanone
90-42-6

d,l-2-cyclohexylcyclohexanone

2-cyclohexylcyclohexanol
6531-86-8

2-cyclohexylcyclohexanol

1,2,3,4,4a,9b-hexahydrodibenzo[b,d]furan
13524-79-3,151123-20-5

1,2,3,4,4a,9b-hexahydrodibenzo[b,d]furan

Conditions
Conditions Yield
With hydrogen; In n-heptane; at 250 ℃; for 2h; under 75007.5 Torr; Autoclave;
dibenzofuran
132-64-9,214827-48-2

dibenzofuran

dodecahydrodibenzofuran
13054-98-3

dodecahydrodibenzofuran

1,2,3,4-tetrahydrodibenzo[b,d]furan
13130-19-3

1,2,3,4-tetrahydrodibenzo[b,d]furan

d,l-2-cyclohexylcyclohexanone
90-42-6

d,l-2-cyclohexylcyclohexanone

2-cyclohexylcyclohexanol
6531-86-8

2-cyclohexylcyclohexanol

2-phenylcyclohexanol
1444-64-0

2-phenylcyclohexanol

2-cyclohexylphenol
119-42-6

2-cyclohexylphenol

1,2,3,4,4a,9b-hexahydrodibenzo[b,d]furan
13524-79-3,151123-20-5

1,2,3,4,4a,9b-hexahydrodibenzo[b,d]furan

Conditions
Conditions Yield
With hydrogen; In n-heptane; at 240 ℃; for 2h; under 75007.5 Torr; Autoclave;
With hydrogen; In n-heptane; at 250 ℃; for 2h; under 75007.5 Torr; Autoclave;
dibenzofuran
132-64-9,214827-48-2

dibenzofuran

1,2,3,4-tetrahydrodibenzo[b,d]furan
13130-19-3

1,2,3,4-tetrahydrodibenzo[b,d]furan

cyclohexylcyclohexane
92-51-3

cyclohexylcyclohexane

1-cyclohexyl-1-cyclohexene
3282-54-0

1-cyclohexyl-1-cyclohexene

d,l-2-cyclohexylcyclohexanone
90-42-6

d,l-2-cyclohexylcyclohexanone

1-phenyl-1-cyclohexane
827-52-1,5379-26-0

1-phenyl-1-cyclohexane

2-cyclohexylcyclohexanol
6531-86-8

2-cyclohexylcyclohexanol

1,2,3,4,4a,9b-hexahydrodibenzo[b,d]furan
13524-79-3,151123-20-5

1,2,3,4,4a,9b-hexahydrodibenzo[b,d]furan

Conditions
Conditions Yield
With hydrogen; In n-heptane; at 240 ℃; for 2h; under 75007.5 Torr; Autoclave;
dibenzofuran
132-64-9,214827-48-2

dibenzofuran

dodecahydrodibenzofuran
13054-98-3

dodecahydrodibenzofuran

1,2,3,4-tetrahydrodibenzo[b,d]furan
13130-19-3

1,2,3,4-tetrahydrodibenzo[b,d]furan

cyclohexylcyclohexane
92-51-3

cyclohexylcyclohexane

d,l-2-cyclohexylcyclohexanone
90-42-6

d,l-2-cyclohexylcyclohexanone

2-cyclohexylcyclohexanol
6531-86-8

2-cyclohexylcyclohexanol

2-phenylcyclohexanol
1444-64-0

2-phenylcyclohexanol

2-cyclohexylphenol
119-42-6

2-cyclohexylphenol

1,2,3,4,4a,9b-hexahydrodibenzo[b,d]furan
13524-79-3,151123-20-5

1,2,3,4,4a,9b-hexahydrodibenzo[b,d]furan

Conditions
Conditions Yield
With hydrogen; In n-heptane; at 240 ℃; for 2h; under 75007.5 Torr; Autoclave;
With hydrogen; In n-heptane; at 240 ℃; for 2h; under 75007.5 Torr; Autoclave;
dibenzofuran
132-64-9,214827-48-2

dibenzofuran

dodecahydrodibenzofuran
13054-98-3

dodecahydrodibenzofuran

1,2,3,4-tetrahydrodibenzo[b,d]furan
13130-19-3

1,2,3,4-tetrahydrodibenzo[b,d]furan

(RS)-2-phenylcyclohexanone
1444-65-1

(RS)-2-phenylcyclohexanone

cyclohexylcyclohexane
92-51-3

cyclohexylcyclohexane

1-cyclohexyl-1-cyclohexene
3282-54-0

1-cyclohexyl-1-cyclohexene

d,l-2-cyclohexylcyclohexanone
90-42-6

d,l-2-cyclohexylcyclohexanone

1-Phenylcyclohexene
771-98-2

1-Phenylcyclohexene

1-phenyl-1-cyclohexane
827-52-1,5379-26-0

1-phenyl-1-cyclohexane

2-cyclohexylcyclohexanol
6531-86-8

2-cyclohexylcyclohexanol

2-phenylcyclohexanol
1444-64-0

2-phenylcyclohexanol

2-cyclohexylphenol
119-42-6

2-cyclohexylphenol

1,2,3,4,4a,9b-hexahydrodibenzo[b,d]furan
13524-79-3,151123-20-5

1,2,3,4,4a,9b-hexahydrodibenzo[b,d]furan

Conditions
Conditions Yield
With hydrogen; at 200 ℃; for 10h; under 9000.9 Torr; Reagent/catalyst;
dibenzofuran
132-64-9,214827-48-2

dibenzofuran

1,2,3,4-tetrahydrodibenzo[b,d]furan
13130-19-3

1,2,3,4-tetrahydrodibenzo[b,d]furan

1-Phenylcyclohexene
771-98-2

1-Phenylcyclohexene

1-phenyl-1-cyclohexane
827-52-1,5379-26-0

1-phenyl-1-cyclohexane

1,2,3,4,4a,9b-hexahydrodibenzo[b,d]furan
13524-79-3,151123-20-5

1,2,3,4,4a,9b-hexahydrodibenzo[b,d]furan

Conditions
Conditions Yield
With hydrogen; at 100 ℃; for 10h; under 9000.9 Torr;
dibenzofuran
132-64-9,214827-48-2

dibenzofuran

1,2,3,4-tetrahydrodibenzo[b,d]furan
13130-19-3

1,2,3,4-tetrahydrodibenzo[b,d]furan

1-cyclohexyl-1-cyclohexene
3282-54-0

1-cyclohexyl-1-cyclohexene

1-Phenylcyclohexene
771-98-2

1-Phenylcyclohexene

1-phenyl-1-cyclohexane
827-52-1,5379-26-0

1-phenyl-1-cyclohexane

Conditions
Conditions Yield
With hydrogen; at 200 ℃; for 10h; under 6000.6 Torr;
dibenzofuran
132-64-9,214827-48-2

dibenzofuran

1,2,3,4-tetrahydrodibenzo[b,d]furan
13130-19-3

1,2,3,4-tetrahydrodibenzo[b,d]furan

d,l-2-cyclohexylcyclohexanone
90-42-6

d,l-2-cyclohexylcyclohexanone

1-Phenylcyclohexene
771-98-2

1-Phenylcyclohexene

1-phenyl-1-cyclohexane
827-52-1,5379-26-0

1-phenyl-1-cyclohexane

1,2,3,4,4a,9b-hexahydrodibenzo[b,d]furan
13524-79-3,151123-20-5

1,2,3,4,4a,9b-hexahydrodibenzo[b,d]furan

Conditions
Conditions Yield
With hydrogen; at 200 ℃; for 1h; under 9000.9 Torr; Time;
dibenzofuran
132-64-9,214827-48-2

dibenzofuran

1,2,3,4-tetrahydrodibenzo[b,d]furan
13130-19-3

1,2,3,4-tetrahydrodibenzo[b,d]furan

cyclohexylcyclohexane
92-51-3

cyclohexylcyclohexane

1-phenyl-1-cyclohexane
827-52-1,5379-26-0

1-phenyl-1-cyclohexane

1,2,3,4,4a,9b-hexahydrodibenzo[b,d]furan
13524-79-3,151123-20-5

1,2,3,4,4a,9b-hexahydrodibenzo[b,d]furan

Conditions
Conditions Yield
With hydrogen; at 275 ℃; under 11251.1 Torr;

Global suppliers and manufacturers

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  • Career Henan Chemical Co
  • Business Type:Lab/Research institutions
  • Contact Tel:+86-371-86658258
  • Emails:purchase@coreychem.com
  • Main Products:1
  • Country:China (Mainland)
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