13280-00-7

Basic information

• Product Name: 3-chloropentan-2-one
• Synonyms: 3-chloropentan-2-one;2-Pentanone, 3-chloro- (6CI,7CI,8CI,9CI)
• CAS NO: 13280-00-7
• Molecular Formula: C₅H₉ClO
• Molecular Weight: 120.57736
• EINECS: 236-282-9
• Product Categories: ACETYLGROUP
• Mol File: 13280-00-7.mol

Chemical Properties

• Boiling Point: 135.2°Cat760mmHg
• Flash Point: 50.5°C
• Appearance: /
• Density: 1.005g/cm³
• Vapor Pressure: 7.8mmHg at 25°C
• Refractive Index: 1.415
• CAS DataBase Reference: 3-chloropentan-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-chloropentan-2-one(13280-00-7)
• EPA Substance Registry System: 3-chloropentan-2-one(13280-00-7)

Safety Data

• Hazardous Substances Data: 13280-00-7(Hazardous Substances Data)

Usage

InChI:InChI=1/C5H9ClO/c1-3-5(6)4(2)7/h5H,3H2,1-2H3

Upstream product

• 7791-25-5 sulfuryl dichloride 
• 107-87-9 2-Pentanone 
• 71-43-2 benzene 
• 7782-50-5 chlorine 
• 39149-66-1 t-butyl 2-ethylacetoacetate 
• 98434-91-4 3-chloro-2-methoxy-2-methyl-valeraldehyde 
• 89581-03-3 2,3-dichloro-2-methylpentanal 
• 51756-08-2 methyl 2-ethyl-3-oxobutanoate 
• 7647-01-0 hydrogenchloride 
• 130000-37-2 2-ethyl-2-chloro-acetoacetic acid ethyl ester 
• 64-19-7 acetic acid 
• 625-35-4 trans-chrotonyl chloride 
• 917-65-7 methylaluminum dichloride 
• 130000-33-8 methyl 2-chloro-2-ethyl-3-oxobutanoate 

Downstream Products

• 1311386-58-9 4-chloro-3-methyl-1-phenylhex-1-yn-3-ol 
• 6116-76-3 3-ethyl-2-methyl-4-oxo-1H-4,5,6,7-tetrahydroindole 
• 69736-37-4 5-Ethyl-4-ethynyl-2,2,4-trimethyl-[1,3]dioxolane 
• 600-14-6 2,3-Pentanedione 
• 1026014-05-0 1-(1-ethyl-2-oxo-propyl)-piperidin-2-one 
• 29025-26-1 3-(2-Methoxy-phenoxy)-pentan-2-one 
• 17649-00-2 3--pentan-2-on 
• 31883-01-9 4-methyl-5-ethylthiazole 

Relevant articles and documents

Novel Regioselective Chlorination of Aliphatic Ketones via Mono-organothallium(III) Derivates

Room temperature reaction of simple aliphatic ketones with an aqueous solution of TiCl3 leads to mono-oxoalkylthalium(III) derivatives followed by formation of selectively α-monochlorinated ketones.

PROCESS FOR PREPARATION OF MOLINDONE

The present invention provides process for preparation of molindone (I) comprising: a) reacting compound with cyclohexane-1,3-dione to form 2-(2-oxopentan-3-yl)cyclohexane-1,3-dione wherein X is Cl, Br or I, b) cyclizing 2-(2-oxopentan-3-yl)cyclohexane-1,

Enantio and diastereoselective addition of phenylacetylene to racemic α-chloroketones

In this report, we have presented the first diastereoselective addition of phenylacetylene to chiral racemic chloroketones. The addition is controlled by the reactivity of the chloroketones that allowed the stereoselective reaction to be performed at -20

CYCLOBUTENEDIONE DERIVATIVES

The present invention relates to compounds of the formula (I): to pharmaceutically acceptable salts therefore and to pharmaceutically acceptable solvates of said compounds and salts, wherein the substituents are defined herein; to compositions containing such compounds; and to the uses of such compounds in the treatment of various diseases, particularly inflammatory conditions.

Lewis Acid-Promoted Coupling Reactions of Acid Chlorides with Organoaluminum and Organozinc Reagents

An efficient synthesis of α,α-unsaturated ketones by the reaction of acid chlorides with trialkyl-aluminum (1/3 mole equiv) in the presence of AlCl3 (1 mol equiv) is described. Dialkylzincs were also useful and are easier to prepare than trialkylaluminum. Reaction of RCOCl with R′AlCl3 or R′2AlCl gave R′COR, without AlCl3, in high yield.

A Convenient Synthesis of 3-Chloro-2-alkanones

3-Chloro-2-alkanones were regiospecifically synthesized from methyl 2-alkyl-3-oxobutanoates by chlorination to afford methyl 2-alkyl-2-chloro-3-oxobutanoates followed by demethoxycarbonylation in acid medium.