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5-Methyl-1,3-thiazole-2-carboxaldehyde is a colorless to pale yellow liquid with a pungent odor. It is a synthetic intermediate used in the production of pharmaceuticals and other organic compounds. This chemical is known for its high flammability and should be handled with caution due to its potential fire hazard when exposed to heat or flame. It is also an irritant to the eyes, skin, and respiratory system, necessitating proper protective measures and working in a well-ventilated area.

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  • 13838-78-3 Structure
  • Basic information

    1. Product Name: 5-Methyl-1,3-thiazole-2-carboxaldehyde
    2. Synonyms: 5-Methylthiazole-2-carboxaldehyde;2-Formyl-5-methyl-1,3-thiazole;5-methyl-2-thiazolecarboxaldehyde;5-Methyl-1,3-thiazole-2-carboxaldehyde;5-methyl-1,3-thiazole-2-carbaldehyde
    3. CAS NO:13838-78-3
    4. Molecular Formula: C5H5NOS
    5. Molecular Weight: 127.1643
    6. EINECS: N/A
    7. Product Categories: Thiazoles, Isothiazoles & Benzothiazoles;Aldehydes;Thiazoles, Isothiazoles &Benzothiazoles
    8. Mol File: 13838-78-3.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 236.0℃
    3. Flash Point: 96.5℃
    4. Appearance: /
    5. Density: 1.270
    6. Vapor Pressure: 0.074mmHg at 25°C
    7. Refractive Index: 1.601
    8. Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
    9. Solubility: N/A
    10. PKA: 0.92±0.10(Predicted)
    11. CAS DataBase Reference: 5-Methyl-1,3-thiazole-2-carboxaldehyde(CAS DataBase Reference)
    12. NIST Chemistry Reference: 5-Methyl-1,3-thiazole-2-carboxaldehyde(13838-78-3)
    13. EPA Substance Registry System: 5-Methyl-1,3-thiazole-2-carboxaldehyde(13838-78-3)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: IRRITANT
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 13838-78-3(Hazardous Substances Data)

13838-78-3 Usage

Uses

Used in Pharmaceutical Industry:
5-Methyl-1,3-thiazole-2-carboxaldehyde is used as a synthetic intermediate for the production of various pharmaceuticals. Its role in the synthesis process is crucial for creating a range of medications that can address different health conditions.
Used in Organic Compounds Production:
5-Methyl-1,3-thiazole-2-carboxaldehyde is used as a synthetic intermediate in the creation of other organic compounds. Its versatility in chemical reactions allows for the development of a wide array of products with various applications in different industries.
Safety Precautions:
5-Methyl-1,3-thiazole-2-carboxaldehyde is used as a hazardous chemical that requires special handling and safety measures. Its flammability and irritant properties necessitate the implementation of proper protective equipment and procedures to ensure the safety of those working with this substance.

Check Digit Verification of cas no

The CAS Registry Mumber 13838-78-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,8,3 and 8 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 13838-78:
(7*1)+(6*3)+(5*8)+(4*3)+(3*8)+(2*7)+(1*8)=123
123 % 10 = 3
So 13838-78-3 is a valid CAS Registry Number.
InChI:InChI=1/C5H5NOS/c1-4-2-6-5(3-7)8-4/h2-3H,1H3

13838-78-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-methyl-1,3-thiazole-2-carbaldehyde

1.2 Other means of identification

Product number -
Other names 5-methyl-2-thiazolylcarboxaldehyde

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:13838-78-3 SDS

13838-78-3Relevant articles and documents

HEPATITIS B VIRUS SURFACE ANTIGEN INHIBITOR

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Paragraph 0204; 0205; 0206, (2020/01/22)

10-oxo-6,1-dihydrobenzo[e]pyrido[1,2-c][1,3]oxazine-9-carboxylic acid derivatives of formula (I) as hepatitis B surface antigen inhibitors or pharmaceutically acceptable salts thereof, and uses of a compound of formula (I) or pharmaceutically acceptable salts thereof and pharmaceutical compositions thereof in preparation of medicaments for treatment of viral hepatitis B.

THIENO[3,2-B] PYRROLE[3,2-D]PYRIDAZINONE DERIVATIVES AND THEIR USE AS PKM2 DERIVATIVES FOR THE TREATMENT OF CANCER, OBESITY AND DIABETES RELATED DISORDERS

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Page/Page column 82-83, (2020/08/28)

Described herein are compounds that regulate pyruvate kinase activity, pharmaceutical compositions and methods of use thereof. These compounds are represented by Formula (I) wherein R2, L1-L2, U1-U7, m, ring A, and Q are as defined herein.

SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF

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Paragraph 0281; 0282, (2014/09/30)

Compounds, compositions and methods are described for inhibiting the TRPC5 ion channel and disorders related to TRPC5.

SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF

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Page/Page column 368, (2014/09/29)

Compounds, compositions and methods are described for inhibiting the TRPC5 ion channel and disorders related to TRPC5.

(3-HYDROXY-4-AMINO-BUTAN-2-YL) -3- (2-THIAZOL-2-YL-PYRROLIDINE-1-CARBONYL) BENZAMIDE DERIVATIVES AND RELATED COMPOUNDS AS BETA-SECRETASE INHIBITORS FOR TREATING

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Page/Page column 85, (2009/05/29)

The present invention provides novel beta-secretase inhibitors and methods for their use, including methods of treating of Alzheimer's disease. (Formula)

Non-covalent thrombin inhibitors featuring P3-heterocycles with P1-monocyclic arginine surrogates

Reiner, John E.,Siev, Daniel V.,Araldi, Gian-Luca,Cui, Jingrong Jean,Ho, Jonathan Z.,Reddy, Komandla Malla,Mamedova, Lala,Vu, Phong H.,Lee, Kuen-Shan S.,Minami, Nathaniel K.,Gibson, Tony S.,Anderson, Susanne M.,Bradbury, Annette E.,Nolan, Thomas G.,Semple, J. Edward

, p. 1203 - 1208 (2007/10/03)

Investigations on P2-P3-heterocyclic dipeptide surrogates directed towards identification of an orally bioavailable thrombin inhibitor led us to pursue novel classes of achiral, non-covalent P1-arginine derivatives. The design, synthesis, and biological activity of inhibitors NC1-NC30 that feature three classes of monocyclic P1-arginine surrogates will be disclosed: (1) (hetero)aromatic amidines, amines and hydroxyamidines, (2) 2-aminopyrazines, and (3) 2-aminopyrimidines and 2-aminotetrahydropyrimidines.

Substituted heterocyclylisoquinolinium salts and compositions and method of use thereof

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, (2008/06/13)

Substitutued heterocyclylisoquinolinium salts, pharmaceutical compositions containing them and methods for the treatment or prevention of neurodegenerative disorders or neurotoxic injuries utilizing them.

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