140-99-8

Basic information

• Product Name: CALCIUM SUCCINATE, MONOHYDRATE
• Synonyms: Butanedioicacid,calciumsalt(1:1);succinicacidcalciummonohydrate;SUCCINIC ACID CALCIUM SALT MONOHYDRATE;CALCIUM SUCCINATE, MONOHYDRATE;BUTANEDIOIC ACID CALCIUM SALT MONOHYDRATE;Calciumsuccinate-1-hydrate;Butanedioic acid, calcium salt;Butanedioic acid,calcium salt
• CAS NO: 140-99-8
• Molecular Formula: 2C₄H₅O₄*Ca
• Molecular Weight: 174.17
• EINECS: 205-445-6
• Mol File: 140-99-8.mol

Chemical Properties

• Boiling Point: 236.1 °C at 760 mmHg
• Flash Point: 110.9 °C
• Appearance: Powder, Flakes, Granular
• Vapor Pressure: 0.0165mmHg at 25°C
• Solubility: 1 M HCl: 100 mg/mL, clear to hazy
• Water Solubility: g/100g H2O: 1.127 (0°C), 1.28 (20°C), 0.66 (100°C) [LAN05]; insoluble alcohol; soluble dilute acids [MER06]
• CAS DataBase Reference: CALCIUM SUCCINATE, MONOHYDRATE(CAS DataBase Reference)
• NIST Chemistry Reference: CALCIUM SUCCINATE, MONOHYDRATE(140-99-8)
• EPA Substance Registry System: CALCIUM SUCCINATE, MONOHYDRATE(140-99-8)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• Hazardous Substances Data: 140-99-8(Hazardous Substances Data)

Usage

Chemical Properties

needles or granules [MER06]

InChI:InChI=1/C4H6O4.Ca/c5-3(6)1-2-4(7)8;/h1-2H2,(H,5,6)(H,7,8);/q;+2/p-2

Upstream product

• 150-90-3 sodium succinate 
• 50-99-7 D-glucose 
• 110-15-6 succinic acid 

Downstream Products

• 7440-06-4 platinum 
• 2226-88-2 diammonium succinate 
• 150-90-3 sodium succinate 
• 106-65-0 Dimethyl succinate 
• 556-32-1 magnesium succinate 

Relevant articles and documents

Method of obtaining complex acidic salts of divalent metals and dicarboxylic acids

A method of obtaining a complex acidic salt of a divalent metal and a dicarboxylic acid includes heating water in a reactor; adding a dicarboxylic acid to the heated water; stirring the water to dissolve the dicarboxylic acid in the heated water to produce a solution or a suspension of the dicarboxylic acid in the heated water; adding MeO to the solution or the suspension, where Me is a divalent metal; continuing the stirring of the solution or suspension until formation of the complex acidic salt Me(AcH)2.nH2O begins, where Ac is an anion of the dicarboxylic acid, and n=0-8; cooling the complex acidic salt to below a temperature of crystallization; sedimenting the complex acidic salt; filtering the complex acidic salt to remove water from the complex acidic salt; and drying the complex acidic salt.

PROCESS FOR MANUFACTURING SUCCINIC ACID

The present invention discloses a Process for the preparation of succinic acid comprising the steps of : a) providing an aqueous medium comprising magnesium succinate by fermentation, wherein a carbohydrate source is fermented by means of a micro-organism to form succinic acid, a magnesium base being added as neutralising agent during fermentation to provide the magnesium succinate; b) subjecting the aqueous medium comprising magnesium succinate to a crystallisation step and a salt exchange step to provide an aqueous solution comprising a monovalent succinate salt, wherein the salt exchange, which is performed either prior to or after crystallisation, comprises treating the magnesium succinate with a monovalent base to provide a magnesium base and the monovalent succinate salt; c) adjusting the concentration of the monovalent succinate salt in the aqueous solution to a value between 10 and 35 wt.%; d) subjecting the aqueous solution comprising the monovalent succinate salt to water-splitting electrodialysis, to produce a first solution comprising monovalent base and a second solution comprising succinic acid and monovalent succinate salt, the electrodialysis being carried out to a partial conversion of 40 to 95 mole%; e) separating the second solution comprising succinic acid and monovalent succinate salt into succinic acid and a solution comprising the monovalent succinate salt by crystallisation; f) recycling the solution of step e) comprising the monovalent succinate salt to step d).

Process for manufacturing succinic acid

The present invention discloses a Process for the preparation of succinic acid comprising the steps of: a) providing an aqueous medium comprising magnesium succinate by fermentation, wherein a carbohydrate source is fermented by means of a micro-organism to form succinic acid, a magnesium base being added as neutralising agent during fermentation to provide the magnesium succinate; b) subjecting the aqueous medium comprising magnesium succinate to a crystallisation step and a salt exchange step to provide an aqueous solution comprising a monovalent succinate salt, wherein the salt exchange, which is performed either prior to or after crystallisation, comprises treating the magnesium succinate with a monovalent base to provide a magnesium base and the monovalent succinate salt; c) adjusting the concentration of the monovalent succinate salt in the aqueous solution to a value between 10 and 35 wt.%; d) subjecting the aqueous solution comprising the monovalent succinate salt to water-splitting electrodialysis, to produce a first solution comprising monovalent base and a second solution comprising succinic acid and monovalent succinate salt, the electrodialysis being carried out to a partial conversion of 40 to 95 mole%; e) separating the second solution comprising succinic acid and monovalent succinate salt into succinic acid and a solution comprising the monovalent succinate salt by crystallisation; f) recycling the solution of step e) comprising the monovalent succinate salt to step d).

METHOD OF MANUFACTURING SUCCINIC ACID AND AMMONIUM SUCCINATE SOLUTIONS

The present invention provides a method of manufacturing a highly pure ammonium succinate solution including the steps of (A) producing calcium succinate trihydrate by crystallization fermentation of a microorganism; (B) converting calcium succinate trihydrate to calcium succinate monohydrate by transition crystallization; (C) separating the calcium succinate monohydrate crystals; (D) substituting the calcium salt in the calcium succinate monohydrate with ammonium salt resulting in an ammonium succinate solution; and (E) removing the solid calcium carbonate from the ammonium succinate solution.