1423027-07-9

Basic information

• Product Name: 3-(4-fluorophenyl)pent-4-enoic acid
• Synonyms: 3-(4-fluorophenyl)pent-4-enoic acid
• CAS NO: 1423027-07-9
• Molecular Weight: 194.206
• Mol File: 1423027-07-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-(4-fluorophenyl)pent-4-enoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-fluorophenyl)pent-4-enoic acid(1423027-07-9)
• EPA Substance Registry System: 3-(4-fluorophenyl)pent-4-enoic acid(1423027-07-9)

Safety Data

• Hazardous Substances Data: 1423027-07-9(Hazardous Substances Data)

Upstream product

• 136265-10-6 ethyl 4-fluorocinnamate 
• 459-57-4 4-fluorobenzaldehyde 
• 78-39-7 Triethyl orthoacetate 
• 124980-95-6 (E)-3-(4-fluorophenyl)-2-propen-1-ol 
• 124980-95-6 3-(4-fluorophenyl)prop-2-en-1-ol 

Downstream Products

• 950838-19-4 (4S,5R)-4-(4-fluorophenyl)-5-(hydroxymethyl)dihydrofuran-2(3H)-one 
• 201855-60-9 (3S,4R)-[1-benzyl-4-piperidin-3-yl-4-(4-fluorophenyl)]methanol 
• 1423027-28-4 (S)-1-benzyl-4-(4-fluorophenyl)piperidin-3-one 
• 1423027-25-1 (3R,4S)-1-benzyl-4-(4-fluorophenyl)piperidin-3-ol 
• 1423027-22-8 (4S,5R)-4-(4-fluorophenyl)-5-hydroxypiperidin-2-one 
• 1423027-19-3 (4S,5R)-5-(azidomethyl)-4-(4-fluorophenyl)dihydrofuran-2(3H)-one 
• 1423027-17-1 ((2R,3S)-3-(4-fluorophenyl)-5-oxotetrahydrofuran-2-yl)methyl methanesulfonate 
• 1423026-35-0 (4S,5S)-4-(4-fluorophenyl)-5-(hydroxymethyl)dihydrofuran-2(3H)-one 
• 1423026-58-7 (R)-methyl 3-(4-fluorophenyl)-3-((R)-oxiran-2-yl)propanoate 
• 1423026-45-2 (R)-methyl 3-(4-fluorophenyl)-3-((S)-oxiran-2-yl)propanoate 

Relevant articles and documents

Rapid Access to Thiolactone Derivatives through Radical-Mediated Acyl Thiol-Ene and Acyl Thiol-Yne Cyclization

A new synthetic approach to thiolactones that employs an efficient acyl thiol-ene (ATE) or acyl thiol-yne (ATY) cyclization to convert unsaturated thiocarboxylic acid derivatives into thiolactones under very mild conditions is described. The high overall yields, fast kinetics, high diastereoselectivity, excellent regiocontrol, and broad substrate scope of these reaction processes render this a very useful approach for diversity-oriented synthesis and drug discovery efforts. A detailed computational rationale is provided for the observed regiocontrol.