14467-69-7

Basic information

• Product Name: Benzene,1,1'-[1,2-ethanediylbis(oxy)]bis[4-nitro-
• Synonyms: Ethane,1,2-bis(p-nitrophenoxy)- (6CI,8CI); 1,2-Bis(4-nitrophenoxy)ethane;1,2-Bis(p-nitrophenoxy)ethane; Ethylene glycol bis(4-nitrophenyl) ether; NSC113230
• CAS NO: 14467-69-7
• Molecular Formula: C14H12 N2 O6
• Molecular Weight: 304.259
• Mol File: 14467-69-7.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 501.7°Cat760mmHg
• Flash Point: 226.1°C
• Density: 1.37g/cm³
• CAS DataBase Reference: Benzene,1,1'-[1,2-ethanediylbis(oxy)]bis[4-nitro-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene,1,1'-[1,2-ethanediylbis(oxy)]bis[4-nitro-(14467-69-7)
• EPA Substance Registry System: Benzene,1,1'-[1,2-ethanediylbis(oxy)]bis[4-nitro-(14467-69-7)

Safety Data

• Hazardous Substances Data: 14467-69-7(Hazardous Substances Data)

Usage

General Description

Benzene,1,1'-[1,2-ethanediylbis(oxy)]bis[4-nitro- is a chemical compound that consists of a benzene ring with two nitro groups attached to it, as well as an ethylene glycol bridge between the two nitro groups. It is commonly used as a raw material in the production of dyes, pharmaceuticals, and pesticides. Additionally, it can also be employed as a solvent and an intermediate in the synthesis of various organic compounds. However, it is important to note that benzene and nitro compounds are known to be toxic and potentially carcinogenic, so caution should be exercised when handling this chemical.

Upstream product

• 56-23-5 tetrachloromethane 
• 104-66-5 1,2-diphenoxyethane 
• 106-93-4 ethylene dibromide 
• 824-78-2 4-nitrophenol sodium salt 
• 10424-18-7 sodium p-nitrophenoxide dihydrate 
• 107-21-1 ethylene glycol 
• 350-46-9 4-Fluoronitrobenzene 
• 100-02-7 4-nitro-phenol 
• 13288-06-7 1-(2-bromoethoxy)-4-nitrobenzene 
• 100-00-5 4-chlorobenzonitrile 
• 7697-37-2 nitric acid 
• 6315-52-2 1,2-bis-tosyloxyethane 
• 1124-31-8 potassium 4-nitrophenolate 
• 16365-27-8 2-(4-nitrophenoxy)ethanol 

Downstream Products

• 6052-10-4 1,2-bis(4-aminophenoxy)ethane 
• 92061-47-7 1,2-bis-(2,4-dinitro-phenoxy)-ethane 
• 37988-01-5 1,2-bis(4-acetamidophenoxy)ethane 

Relevant articles and documents

Discovery of Diphenoxy Derivatives with Flexible Linkers as Ligands for β-Amyloid Plaques

The highly rigid and planar scaffolds with π-conjugated systems have been widely considered to be indispensable for β-amyloid (Aβ) binding ligands. In this study, a library of diphenoxy compounds with different types of more flexible linkers as Aβ ligands were synthesized and evaluated. Most of them displayed good affinity (Ki1-42aggregates, and some ligands even showed values of Kiless than 10 nM. Structure-activity relationship analysis revealed that modification on the linkers or substituents tolerated great flexibility, which challenged the long-held belief that rigid and planar structures are exclusively favored for Aβ binding. Three ligands were labeled by iodine-125, and they exhibited good properties in vitro and in vivo, which further supported that this flexible scaffold was potential and promising for the development of Aβ imaging agents.

Liquid crystal dimers having vary oxyethylene flexible spacers

In this article, we are prepared that the liquid crystal dimers have aromatic-ester type mesogenic units or aromatic-Schiff base type mesogonic units and confirmed by 1H-NMR spectrometry. The mesomorphic and optical properties of the resultant dimers were studied by differential scanning calorimetry and polarizing optical microscopy.

Alkoxylation of 4-chloronitrobenzene with aliphatic alcohols and glycols in the presence of NaOH

The reaction of 4-chloronitrobenzene with aliphatic C1-n-C 4 alcohols and with mono-, di-, and triethylene glycols in the presence of NaOH in liquid ammonia at 15-50°C was studied.