1638-63-7Relevant articles and documents
Ligand-Enabled Meta-C-H Alkylation and Arylation Using a Modified Norbornene
Shen, Peng-Xiang,Wang, Xiao-Chen,Wang, Peng,Zhu, Ru-Yi,Yu, Jin-Quan
supporting information, p. 11574 - 11577 (2015/09/28)
2-Carbomethoxynorbornene is identified as a more effective transient mediator to promote a Pd(II)-catalyzed meta-C(sp2)-H alkylation of amides with various alkyl iodides as well as arylation with previously incompatible aryl iodides. The use of a tailor-made quinoline ligand is also crucial for this reaction to proceed.
SUBSTITUTED CYCLOHEXYL-1,4-DIAMINE DERIVATIVES WITH A CHAIN EXTENSION
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Page/Page column 25, (2008/06/13)
The invention relates to substituted cyclohexyl-1,4-diamine derivatives, to a method for their production, to medicaments containing said compounds and to the use of substituted cyclohexyl-1,4-diamine derivatives for producing medicaments.
Asymmetric induction in the cycloaddition of a mandeloylnitroso compound and penta-1,3-diene: X-ray crystal structure analysis of two N-mandeloyldihydrooxazines
Freer, Andrew A.,Isaacs, Neil W.,Kirby, Gordon W.,Snedden, Peter,Tierney, Sean G. T.
, p. 601 - 621 (2007/10/03)
Oxidation of (+/-)-mandelohydroxamic acid with tetraethylammonium periodate in the presence of (E)-penta-1,3-diene at 0 deg C gave a mixture of 4 racemic cycloadducts of the derived, transient acylnitroso compound (+/-)-2.The 6-methyl 5 and 6 and 3-methyl 7 and 8 pairs of diastereoisomeric dihydro-oxazines were obtained in the ratio 3.0 : 1 : 1.2 :1.2 , respectively.The relative configurations of the racemic cycloadducts 5 and 7 were determined by X-ray crystallography.The relative asymmetric inductions observed for the pairs of regioisomers 5 and 6 and 7 and 8 are briefly discussed.