16657-07-1

Basic information

• Product Name: 1H-Indene, 7-bromo-
• Synonyms: 1H-Indene, 7-bromo-
• CAS NO: 16657-07-1
• Molecular Formula: C₉H₇Br
• Molecular Weight: 195.0585
• EINECS: 663-059-7
• Mol File: 16657-07-1.mol

Chemical Properties

• Boiling Point: 257.0±29.0 °C(Predicted)
• Flash Point: >110℃
• Appearance: /
• Density: 1.453 g/mL at 25 °C
• Refractive Index: 1.6078 (589.3 nm 25℃)
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 1H-Indene, 7-bromo-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Indene, 7-bromo-(16657-07-1)
• EPA Substance Registry System: 1H-Indene, 7-bromo-(16657-07-1)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• WGK Germany: 3
• Hazardous Substances Data: 16657-07-1(Hazardous Substances Data)

Usage

Uses

Used in Chemical Research:
1H-Indene, 7-bromois used as a research compound for studying the properties and reactions of bromoindene derivatives. Its unique structure allows chemists to explore various chemical pathways and interactions, contributing to the broader understanding of organic chemistry.
Used in Pharmaceutical Research:
1H-Indene, 7-bromois employed as a starting material or intermediate in the synthesis of pharmaceutical compounds. Its specific structure and reactivity make it a valuable component in the development of new drugs, particularly those targeting specific biological pathways or receptors.
Used in Material Science:
1H-Indene, 7-bromois utilized in the development of new materials with unique properties, such as advanced polymers or composites. Its chemical structure can influence the physical and chemical characteristics of these materials, leading to potential applications in various industries.

Upstream product

• 90725-40-9 3-(2-bromophenyl)propanoyl chloride 
• 66192-11-8 diethyl 2-(2-bromobenzyl)propan-1,3-dioate 
• 15115-60-3 4-bromo-2,3-dihydroinden-1-one 
• 15115-58-9 3-(2-bromophenyl)propionic acid 
• 16657-10-6 (±)-4-bromo-2,3-dihydro-1H-inden-1-ol 
• 98-29-3 4-tert-Butylcatechol 
• 104-15-4 toluene-4-sulfonic acid 
• 3433-80-5 1-Bromo-2-bromomethyl-benzene 
• 58380-12-4 <(2-bromophenyl)methyl>propanedicarboxylic acid 

Downstream Products

• 846032-36-8 4-bromo-1,3-dihydro-2H-inden-2-one 
• 124067-30-7 4-Methoxy-indan-2-one 
• 125141-73-3 4-bromo-2,3-dihydro-1H-inden-2-ol 
• 78383-19-4 7-phenylindene 

Relevant articles and documents

FUSED PYRAZOLE AND IMIDAZOLE BASED COMPOUNDS AND USE THEREOF AS GLI1 INHIBITORS

The present invention is directed to a composition and a method for use thereof, such as for the treatment and prevention of a neurological disorder or cancer in a subject.

S1P1 AGONIST AND APPLICATION THEREOF

The present invention relates to a class of tricyclic compounds and an application thereof as a sphingosine 1-phosphate type 1 (S1P1) receptor agonist. The invention specifically relates to a compound represented by formula (II), and a tautomer and pharmaceutically acceptable salt of same.

Enantioselective Synthesis of Chiral Indane Derivatives by Rhodium-Catalyzed Addition of Arylboron Reagents to Substituted Indenes

Rhodium-catalyzed asymmetric addition of arylboron reagents to indene derivatives proceeded to give 2-arylindanes in good yields with high enantioselectivity. Deuterium-labeling experiments indicated that the present reaction involved a 1,4-Rh shift from an initially formed benzylrhodium to an arylrhodium intermediate before protonation leading to the corresponding addition product. The asymmetric addition was also successful for acenaphthylene, which has a similar skeleton to indene, where it was found that the benzylrhodium intermediate underwent direct protonation without the 1,4-Rh shift.

Metallocenes and catalyst compositions derived therefrom

This invention relates to a novel group 2, 3 or 4 transition metal metallocene catalyst compound that is asymmetric having two non-identical indenyl ligands with substitution at R2 having a branched or unbranched C1-C20 alkyl group substituted with a cyclic group or a cyclic group, R8 is an alkyl group and R4 and R10 are substituted phenyl groups.

BRIDGED BIS(INDENYL) TRANSITIONAL METAL COMPLEXES, PRODUCTION, AND USE THEREOF

The invention relates to a novel group bridged metallocene transition metal complexes, wherein the complex includes at least one indenyl ligand substituted at the 4- position with a phenyl group, the 4-phenyl group being preferably substituted at the 3 ', 4', and 5' positions with particular combinations of substituents, particularly wherein the 4'- substituent is a group of the formula (XR'n)-, wherein X is a Group 14-17 heteroatom having an atomic weight of 13 to 79 and R' is one of a hydrogen atom, halogen atom, a C1-C10 alkyl group, or a C6-C10 aryl group and n is 0, 1, 2, or 3. Catalyst systems including the transition metal complex, polymerization processes using the transition metal complex, and polymers made using the transition metal complex are also described.

1,2,3-trisubstituted indanes by highly diastereoselective palladium-catalyzed oxyarylation of indenes with arylboronic acids and nitroxides

Chemecal quation presented Excellent stereoselectivity is obtained in the synthesis of biologically interesting 1,2,3-trisubstituted indanes B by the reaction of readily prepared 3-substituted indenes A with commercially available arylboronic acids by using various TEMPO derivatives as external oxidants and Pd(OAc)2 as a catalyst. The anti,anti isomers are formed and reactions occur stereospecifically under mild conditions.

SPIROAMINOOXAZOLINE ANALOGUES AS ALPHA2C ADRENERGIC RECEPTOR MODULATORS

In its many embodiments, the present invention provides a novel class of spiroaminooxazoline analogues as modulators of α2C adrenergic receptor, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more conditions associated with the α2C adrenergic receptors using such compounds or pharmaceutical compositions.

Pyrethrinoid esters carrying an indanyl nucleus and their use as pesticides

Pyrenthrinoid esters with an indenyl nucleus having the following structural formula STR1 wherein the substituents are herein defined, have been shown to be useful as pesticides and in pesticidal compositions.

Synthesis of Biological Markers in Fossil Fuels. 2. Synthesis and 13C NMR Studies of Substituted Indans and Tetralins

Unambiguous syntheses of all possible methyl, ethyl, n-propyl, and n-butyl derivatives of indan and tetralin were developed using the Kumada coupling procedure involving the reaction of aryl or vinyl halides with Grignard reagents in the presence of nickel(II) chloride.An analysis of the 13C NMR spectra of these compounds was also completed.