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2-oxobutanoyl chloride is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 17118-74-0 Structure
  • Basic information

    1. Product Name: 2-oxobutanoyl chloride
    2. Synonyms: 2-oxobutanoyl chloride;Butanoyl chloride, 2-oxo-
    3. CAS NO:17118-74-0
    4. Molecular Formula: C4H5ClO2
    5. Molecular Weight: 120.5343
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 17118-74-0.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 158.5±23.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.203±0.06 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 2-oxobutanoyl chloride(CAS DataBase Reference)
    10. NIST Chemistry Reference: 2-oxobutanoyl chloride(17118-74-0)
    11. EPA Substance Registry System: 2-oxobutanoyl chloride(17118-74-0)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 17118-74-0(Hazardous Substances Data)

17118-74-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 17118-74-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,7,1,1 and 8 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 17118-74:
(7*1)+(6*7)+(5*1)+(4*1)+(3*8)+(2*7)+(1*4)=100
100 % 10 = 0
So 17118-74-0 is a valid CAS Registry Number.

17118-74-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-Oxobutanoyl chloride

1.2 Other means of identification

Product number -
Other names ethyl oxalylchloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:17118-74-0 SDS

17118-74-0Relevant articles and documents

A single-step synthesis of xyridins A and B, metabolites from Xyris indica

Saeed, Aamer

, p. 967 - 972 (2005)

A facile single-step synthesis of the title isocoumarins isolated from Xyris indica has been elaborated. Condensation of butanoyl chloride and 2-oxobutanoyl chloride with 3,4-methylenedioxyhomophthalic acid afforded xyridin A and xyridin B, respectively. Xyridin A was saponified to the corresponding keto acid, which on reduction gave the (±)-3,4-dihydro-6,7- methylenedioxy-3-propylisocoumarin in which diastereotopy of the methylenic protons around the stereogenic center was observed. A mass fragmentation mechanism for xyridins has also been suggested.

Exploiting the Reactivity of 1,2-Ketoamides: Enantioselective Synthesis of Functionalized Pyrrolidines and Pyrrolo-1,4-benzodiazepine-2,5-diones

Acosta, Paola,Becerra, Diana,Goudedranche, Sébastien,Quiroga, Jairo,Constantieux, Thierry,Bonne, Damien,Rodriguez, Jean

, p. 1591 - 1595 (2015)

A new strategy for the synthesis of optically active pyrrolo[1,4]benzodiazepine-2,5-diones has been developed. The approach is based on an initial Michael addition of functionalized 1,2-ketoamides on nitroalkenes, with a reduction-double cyclization seque

Hydroxoiridium/Chiral Diene Complexes as Effective Catalysts for Asymmetric Annulation of α-Oxo- and Iminocarboxamides with 1,3-Dienes

Hatano, Miyuki,Nishimura, Takahiro

supporting information, p. 10949 - 10952 (2015/09/15)

The asymmetric [3+2] annulation of α-oxo- and α-iminocarboxamides with 1,3-dienes catalyzed by hydroxoiridium/chiral diene complexes was realized, giving high yields of the corresponding γ-lactams with high enantioselectivity. [3+2] annulation: The asymme

Cationic Ir/Me-BIPAM-catalyzed asymmetric intramolecular direct hydroarylation of α-ketoamides

Shirai, Tomohiko,Ito, Hajime,Yamamoto, Yasunori

supporting information, p. 2658 - 2661 (2014/03/21)

Asymmetric intramolecular direct hydroarylation of α-ketoamides gives various types of optically active 3-substituted 3-hydroxy-2-oxindoles in high yields with complete regioselectivity and high enantioselectivities (84-98 % ee). This is realized by the use of the cationic iridium complex [Ir(cod) 2](BArF4) and the chiral O-linked bidentate phosphoramidite (R,R)-Me-BIPAM. Carbon's got a brand new bond: Asymmetric intramolecular direct hydroarylation of α-ketoamides gives various optically active 3-substituted 3-hydroxy-2-oxindoles in high yields with complete regioselectivity and high enantioselectivities. This is realized by the use of an asymmetric cationic iridium complex formed in situ (see Scheme).

A new class of tunable dendritic diphosphine ligands: Synthesis and applications in the Ru-catalyzed asymmetric hydrogenation of functionalized ketones

Ma, Baode,Miao, Tingting,Sun, Yihua,He, Yanmei,Liu, Ji,Feng, Yu,Chen, Hui,Fan, Qing-Hua

supporting information, p. 9969 - 9978 (2014/08/18)

A series of tunable G0-G3 dendritic 2,2'-bis(diphenylphosphino)-1,1'-binaphthyl (BINAP) ligands was prepared by attaching polyaryl ether dendrons onto the four phenyl rings on the P atoms. Their ruthenium complexes were employed in the asymmetric hydrogenation of β-ketoesters, α-ketoesters, and α-ketoamides to reveal the effects of dendron size on the catalytic properties. The second- and third-generation catalysts exhibited excellent enantioselectivities, which are remarkably higher than those obtained from the small molecular catalysts and the first-generation catalyst. Molecular modeling indicates that the incorporation of bulky dendritic wedges can influence the steric environments around the metal center. In addition, the ruthenium catalyst bearing a second-generation dendritic ligand could be recycled and reused seven times without any obvious decrease in enantioselectivity.

A temporary-bridge strategy for enantioselective organocatalyzed synthesis of aza-seven-membered rings

Goudedranche, Sbastien,Pierrot, David,Constantieux, Thierry,Bonne, Damien,Rodriguez, Jean

supporting information, p. 15605 - 15608 (2015/01/08)

We report the first enantioselective organocatalyzed domino synthesis of azepane moieties. This temporary-bridge strategy is based on a conceptually original annulation of ambident electrophilic and 1,4-bis-nucleophilic α-ketoamides with 1,3-bis-electrophilic enals. The obtained oxygen-bridged azepanes can be selectively transformed into optically active azepanone, azepanol or azepanedione derivatives of high synthetic value. This journal is

Reactive spin state dependent enantiospecific photocyclization of axially chiral α-substituted acrylanilides

Ayitou, Anoklase Jean-Luc,Sivaguru

supporting information; experimental part, p. 2568 - 2570 (2011/04/26)

The enantiomeric ratio (e.r.) in the 3,4-dihydroquinolin-2-one photoproduct during 6π-photocyclization of α-substituted axially chiral ortho-tert-butyl-acrylanilides depends on the nature of the reactive spin state (singlet or triplet), where the singlet-

Diastereoselective allylation of α-ketoamides bearing camphor N-tosylpyrazolidinone auxiliary: Efficient synthesis of highly optically active two stereoisomers

Chen, Jung-Hsuan,Venkatesham, Uppala,Lee, Li-Chen,Chen, Kwunmin

, p. 887 - 893 (2007/10/03)

Complementary allylation conditions were developed for the synthesis of both diastereomers of tertiary homoallylic alcohols. Treatment of camphor N-tosylpyrazolidinone derived α-ketoamides with allyltributylstannane afforded both the individual homoallyli

Total Syntheses of (±)-Anchinopeptolide D and (±)-Cycloanchinopeptolide D

Snider, Barry B.,Song, Fengbin,Foxman, Bruce M.

, p. 793 - 800 (2007/10/03)

The first synthesis of (±)-anchinopeptolide D (4) has been accomplished in seven steps in 10% overall yield from octopamine hydrochloride (17), N-(Boc)glycine (16), and 5-amino-2-hydroxypentanoic acid (22). The key step is the aldol dimerization and hemiaminal formation of α-keto amide 26, which gives primarily protected anchinopeptolide D 27 under kinetically controlled conditions. Cycloanchinopeptolide D (31) has been prepared by the unprecedented head-to-head photodimerization of the two hydroxystyrylamides of 4 using the hydrophobic effect in water to force the two side chains into close proximity so that [2 + 2] cycloaddition is faster than trans to cis double bond isomerization. Coupling of amine 21 with pyroglutamic acid affords the naturally occurring tripeptide 35, which had been assigned glutamic acid structure 34.

Electro-organic synthesis 68.1 diastereoselective cathodic reduction of phenylglyoxylic acid attached to chiral auxiliaries

Reufer, Christian,Zielinski, Claudia,Schaefer, Hans Juergen,Froehlich, Roland

, p. 1023 - 1037 (2007/10/03)

Two chiral auxiliaries were attached to phenylglyoxylic acid as amides in 67-70% yield. Cyclic voltammetry of one amide in acetonitrile-pivalic acid (0.117 mol 1-1) shows that it is irreversibly reduced at -0.73 to -1.07 V (vs. Ag/AgCl) dependi

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