16703-52-9 Usage
Description
ETHYL N,N-DIMETHYLOXAMATE, with the molecular formula C5H11NO3, is a clear, colorless liquid chemical compound. It is derived from oxamic acid and is widely recognized for its utility as a solvent and reagent in organic synthesis. ETHYL N,N-DIMETHYLOXAMATE is also frequently employed as a protecting group for amines in peptide synthesis, and it serves as a precursor in the production of other organic compounds. ETHYL N,N-DIMETHYLOXAMATE is noted for its relative stability and non-toxic nature, presenting minimal environmental and health risks when managed and applied correctly.
Uses
Used in Organic Synthesis:
ETHYL N,N-DIMETHYLOXAMATE is used as a solvent and reagent for its ability to facilitate various chemical reactions in organic synthesis processes. Its properties make it a valuable component in the creation of a range of organic compounds.
Used as a Protecting Group in Peptide Synthesis:
In the pharmaceutical and biotechnological industries, ETHYL N,N-DIMETHYLOXAMATE is utilized as a protecting group for amines during peptide synthesis. This application is crucial for preventing unwanted side reactions and ensuring the correct formation of peptide bonds.
Used in Production of Other Organic Compounds:
ETHYL N,N-DIMETHYLOXAMATE also serves as a precursor in the synthesis of other organic compounds, contributing to the development of new chemical entities for various applications across different industries.
Check Digit Verification of cas no
The CAS Registry Mumber 16703-52-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,7,0 and 3 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 16703-52:
(7*1)+(6*6)+(5*7)+(4*0)+(3*3)+(2*5)+(1*2)=99
99 % 10 = 9
So 16703-52-9 is a valid CAS Registry Number.
InChI:InChI=1/C6H11NO3/c1-4-10-6(9)5(8)7(2)3/h4H2,1-3H3
16703-52-9Relevant articles and documents
Donatsch et al.
, p. 1185 (1970)
SUBSTITUTED HETEROARYL COMPOUNDS AND METHODS OF USE
-
Paragraph 000667, (2019/06/05)
The present invention provides novel heteroaryl compounds, pharmaceutical acceptable salts and formulations thereof. They are useful in preventing, managing, treating or lessening the severity of a protein kinase-mediated disease. The invention also provides pharmaceutically acceptable compositions comprising such compounds and methods of using the compositions in the treatment of protein kinase-mediated disease.
Synthesis of 2,3-allenylamides utilizing [1,2]-phospha-Brook rearrangement and their application to gold-catalyzed cycloisomerization providing 2-aminofuran derivatives
Kondoh, Azusa,Ishikawa, Sho,Aoki, Takuma,Terada, Masahiro
supporting information, p. 12513 - 12516 (2016/10/24)
An efficient synthetic method for 2,3-allenylamides having an oxygen functionality at the 2-position, which are difficult to access by conventional methods, was newly developed by utilizing the [1,2]-phospha-Brook rearrangement under Br?nsted base catalysis. Further manipulation of the 2,3-allenylamides via gold-catalyzed cycloisomerization enables the formation of 2-aminofuran derivatives.
