18305-60-7Relevant articles and documents
Controlled hydrogenation of diphenylacetylene using alkylammonium formate
Suzuki, Hideyuki,Satoh, Ikkyu,Nishioka, Hiromi,Takeuchi, Yasuo
supporting information, p. 3834 - 3837 (2017/09/15)
A simple and straightforward semihydrogenation of alkyne to alkene with triethanolamine and formic acid in the presence of PdCl2 has been described. Although hydrogenation using formic acid as a hydrogenation source has been used in combination with amines previously, few reports are available concerning the associated reactivity. We demonstrated that reactivity changes depending on the type of amine used in the hydrogenation. Further, this reaction requires no strict time control, making it a useful tool in organic synthesis.
Carboxylic acid production of tertiary butyl
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Paragraph 0075, (2016/12/22)
PROBLEM TO BE SOLVED: To provide a process for producing a carboxylic acid tert-butyl ester industrially advantageously.SOLUTION: The process for producing a carboxylic acid tert-butyl ester includes reacting compounds represented by formula (1) and formula (2) (wherein Y denotes a 1-20C alkoxy group) with isobutene in the presence of an acid catalyst and at normal pressure by using a mixed solvent containing an aromatic hydrocarbon.
Production of fumaric acid ester
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Paragraph 0034; 0040, (2016/12/16)
PROBLEM TO BE SOLVED: To produce di-tert-butyl fumarate in a high yield. SOLUTION: A production method of di-tert-butyl fumarate is provided, which includes the steps of: reacting maleic acid with 2-methyl propylene in a specific solvent by use of an acid catalyst to obtain di-tert-butyl maleate; and isomerizing the compound into di-tert-butyl fumarate in the presence of an isomerization catalyst. COPYRIGHT: (C)2012,JPOandINPIT
Cyclopropanation of olefins with diazo compounds catalyzed by a dicopper-substituted silicotungstate [γ-H2SiW 10O36Cu2(μ-1,1-N3) 2]4-
Kamata, Keigo,Kimura, Toshihiro,Mizuno, Noritaka
supporting information; experimental part, p. 702 - 703 (2011/01/08)
The dicopper-substituted γ-Keggin silicotungstate (TBA) 4[γ-H2SiW10O36Cu 2II(μ-1,1-N3)2] (I, TBA = tetra-n-butylammonium) could act as an efficient precatalyst for the chemoselective cylopropanation of olefins with diazo compounds. Various kinds of olefins were efficiently converted to the corresponding cyclopropane derivatives in good yields.
Highly chemo- and stereoselective intermolecular coupling of diazoacetates to give cis-olefins by using Grubbs second-generation catalyst
Hodgson, David M.,Angrish, Deepshikha
, p. 3470 - 3479 (2008/02/08)
Highly stereoselective formation of cis-2-ene-1,4-diesters by homo- and heterocoupling of α-diazoacetates in the presence of Grubbs second-generation catalyst is demonstrated. The dual reactivity of the catalyst in alkene metathesis and diazocoupling has been exploited in the synthesis of 12-26-membered macrocyclic dienyl dilactones by one-pot carbene dimerisation/ring-closing metathesis.
Maleates from diazoacetates and dilactones from head-to-head dimerisation of alkenyl diazoacetates using Grubbs' 2nd-generation ruthenium carbene catalyst
Hodgson, David M.,Angrish, Deepshikha
, p. 4902 - 4904 (2007/10/03)
Grubbs' 2nd-generation ruthenium carbene catalyst homocouples diazoacetates to maleates and also catalyses head-to-head dimerisation of alkenyl diazoacetates giving dienyl dilactones. The Royal Society of Chemistry 2005.
Concave reagents 32: Syn- and anti-selective cyclopropanation of alkenes with diazoacetates catalyzed by copper(I) complexes of concave 1,10- phenanthrolines
L?ffler, Frank,Hagen, Martin,Lüning, Ulrich
, p. 1826 - 1828 (2007/10/03)
Two classes of concave 1,10-phenanthroline ligands 1 and 2 have been used in the copper(I) catalyzed cyclopropanation of several acyclic and cyclic alkenes 3 with three diazoacetates 4-6. The bimacrocyclic 2,9-diaryl- 1,10-phenanthrolines 1 favor the anti(trans- or exo-) cyclopropanation with anti/syn-selectivities of up to > 99:1 (8g). In contrast, with the 1,10- phenanthroline bridged calix[6]arenes 2 as ligands a rarely observed syn- selective cyclopropanation was achieved. Methyl diazoacetate (6) showed the best syn-selectivities with anti/syn-ratios of up to 14:86 (9g).
Highly cis- and enantioface-selective cyclpropanation using (R,R)-Ru- salen complex: Solubility dependent enantioface selection
Uchida, Tatsuya,Irie, Ryo,Katsuki, Tsutomu
, p. 1793 - 1795 (2007/10/03)
The reaction of styrene and t-butyl α-diazoacetate in the presence of (R,R)-(ON+)(salen)ruthenium(II) complex 1 under the irradiation of incandescent light in THF gave the corresponding (IS,2R)- cyclopropanecarboxylate with high stereoselectivi
Efficient and Stereoselective Synthesis of J-104,118, A Novel, Potent Inhibitor of Squalene Synthase
Iwasawa, Yoshikazu,Nonoshita, Katsumasa,Tomimoto, Koji
, p. 7459 - 7462 (2007/10/02)
J-104,118, a novel and potent inhibitor of squalene synthase, was synthesized stereoselectively.The chiral amine 1 was efficiently synthesized by Sharpless asymmetric dihydroxylation as a key reaction.
Ruthenium(II)Cl2-Bis(oxazolinyl)bipyridine Complex. Its Structure and Reactivity
Nishiyama, Hisao,Park, Soon-Bong,Haga, Masa-aki,Aoki, Katsuyuki,Itoh, Kenji
, p. 1111 - 1114 (2007/10/02)
A mixture of 2 and 6,6'-bis(oxazolinyl)-2,2'-bipyridine (Bipymox-ip) was heated in ethanol at 70 deg C to produce Ru(II)Cl2(Bipymox-ip), of which structure was clarified by X-ray analysis to show that Bipymox-ip binds as a tetradentate ligand.Its catalytic activities for transformations of diazoacetates in dimerization and cyclopropanation with styrene were examined and its spectroelectrochemistry was studied.
