2050-25-1

Basic information

• Product Name: 2-[2-(BENZYLOXY)ETHOXY]ETHANOL
• Synonyms: 2-[2-(BENZYLOXY)ETHOXY]ETHANOL;DI(ETHYLENE GLYCOL) BENZYL ETHER;DIETHYLENE GLYCOL MONOBENZYL ETHER;2-[2-(phenylmethoxy)ethoxy]-Ethanol;5-(Benzyloxy)-3-oxapentane-1-ol;Benzyl-PEG3-alcohol;Benzyl-PEG2-alcohol;Di(ethylene glycol) benzyl ether 97%
• CAS NO: 2050-25-1
• Molecular Formula: C₁₁H₁₆O₃
• Molecular Weight: 196.24
• Mol File: 2050-25-1.mol

Chemical Properties

• Boiling Point: 80-110 °C0.5 mm Hg(lit.)
• Flash Point: >230 °F
• Appearance: /
• Density: 1.094 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.000245mmHg at 25°C
• Refractive Index: n20/D 1.51(lit.)
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 14.36±0.10(Predicted)
• Water Solubility: Soluble in water
• CAS DataBase Reference: 2-[2-(BENZYLOXY)ETHOXY]ETHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[2-(BENZYLOXY)ETHOXY]ETHANOL(2050-25-1)
• EPA Substance Registry System: 2-[2-(BENZYLOXY)ETHOXY]ETHANOL(2050-25-1)

Safety Data

• Safety Statements: 24/25
• WGK Germany: 3
• Hazardous Substances Data: 2050-25-1(Hazardous Substances Data)

Usage

Uses

Used in Polymer Synthesis:
2-[2-(Benzyloxy)ethoxy]ethanol is used as an initiator in the preparation of linear-PLA (poly(L-lactide)) for enhancing the properties of the resulting polymer.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2-[2-(Benzyloxy)ethoxy]ethanol is used as a protecting group for various chemical reactions, particularly in the synthesis of complex molecules. The acid-labile benzyl group can be selectively removed under acidic conditions, allowing for the controlled release of the active compound.
Used in Drug Delivery Systems:
2-[2-(Benzyloxy)ethoxy]ethanol is used as a component in the design of drug delivery systems, where its hydrophilic PEG linker can improve the solubility and bioavailability of drugs in the body. This can lead to enhanced therapeutic outcomes and reduced side effects.
Used in Chemical Synthesis:
In chemical synthesis, 2-[2-(Benzyloxy)ethoxy]ethanol is used as a versatile building block for the creation of various compounds, taking advantage of its reactive primary alcohol and acid-labile benzyl group for further functionalization and protection of sensitive functional groups.
Used in Cosmetics and Personal Care Industry:
In the cosmetics and personal care industry, 2-[2-(Benzyloxy)ethoxy]ethanol is used as an ingredient in formulations due to its ability to improve the solubility of other components, enhance the stability of the final product, and provide a pleasant texture and feel to the consumer.

InChI:InChI=1/C11H16O3/c12-6-7-13-8-9-14-10-11-4-2-1-3-5-11/h1-5,12H,6-10H2

Upstream product

• 75-21-8 oxirane 
• 100-51-6 benzyl alcohol 
• 100-44-7 benzyl chloride 
• 111-46-6 diethylene glycol 
• 100-39-0 benzyl bromide 
• 17229-17-3 benzyl 2-chloroethyl ether 
• 7388-28-5 sodium 2-hydroxyethoxide 
• 107-07-3 2-chloro-ethanol 
• 622-08-2 2-Benzyloxyethanol 

Downstream Products

• 2088-48-4 Benzylether von Monopentoxymethylether des Diethylenglykols 
• 6794-01-0 2-Hexyloxymethoxy-2'-benzyloxy-diethylether 
• 6875-85-0 2-Isobutyloxymethoxy-2'-benzyloxy-diethylether 
• 6794-03-2 2-Diethylaminomethoxy-2'-benzyloxy-diethylether 
• 6794-02-1 2-<2-Cyan-ethoxy>-2'-benzyloxy-diethylether 
• 6913-77-5 2-Butyloxymethoxy-2'-benzyloxy-diethylether 
• 93206-09-8 <2-(benzyloxy)ethoxy>acetic acid 
• 127457-61-8 3-[2-(2-Benzyloxy-ethoxy)-ethoxy]-propionic acid methyl ester 
• 91842-53-4 10-phenyl-3,6,9-trioxadecanoic acid 
• 98627-22-6 2-<2-(phenylmethoxy)ethoxy>ethanol 4-methylbenzenesulfonate 
• 159526-75-7 (2S)-(+)-methyl 2-(N-benzyloxycarbonylamino)-9-benzyloxy-4,7-dioxanonanoate 
• 81731-01-3 benzyloxyethoxyethyl chloroformate 
• 6875-83-8 di(ethylene glycol) benzyl methoxymethyl ether 
• 150272-33-6 di(ethylene glycol)monobenzyl ether methanesulfonate 

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