2050-25-1Relevant articles and documents
Antibody drug conjugate, intermediate, preparation method, pharmaceutical composition and uses thereof
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Page/Page column 108; 110, (2019/11/11)
Disclosed are an antibody drug conjugate IB, which uses ether linkages for connection, and improves the water solubility, stability and cytotoxicity in vivo and in intro, and an intermediate, a pharmaceutical composition, and uses of the antibody drug conjugate. The antibody drug conjugate has simple synthetic steps and a high yield.
Aryl substituted phosphorothio amine derivatives and their use in medical application
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Paragraph 0149-0153, (2017/09/12)
The invention relates to an aryl-substituted phosphonaminate and an application of the aryl-substituted phosphonaminate in medical science, in particular to an aryl-substituted phosphonaminate showed in a general formula (I), stereoisomer of the aryl-subs
8034
Suthagar, Kajitha,Watson, Andrew J.A.,Wilkinson, Brendan L.,Fairbanks, Antony J.
, p. 153 - 166 (2015/08/24)
Abstract A series of arabinose glycosyl sulfamides with varying alkyl chain types and lengths were synthesised as mimics of decaprenolphosphoarabinose (DPA), and as potential inhibitors of mycobacterial cell wall biosynthesis. Unprecedented conversion of