23190-16-1

Basic information

• Product Name: (1R,2S)-2-Amino-1,2-diphenylethanol
• Synonyms: (1R,2S)-(-)-2-AMINO-1,2-DIPHENYLETHANOL;(1R,2S)-2-AMINO-1,2-DIPHENYLETHANOL;(1R,2S)-(-)-DIPHENYL-2-AMINOETHANOL;(1R,2S)-(-)-ERYTHRO-2-AMINO 1,2-DIPHENYLETHANOL;BENZENEETHANOL, B-AMINO-A-PHENYL-, (AR,BS)-;(1R,2S)-(-)-amino-1,2,-diphenylethanol;(1R,2S)-(-)-2-Amino-1,2-dipenylethanol;(1R,2S)-(-)-1,2-DIPHENYLHYDROXYETHYLAMINE
• CAS NO: 23190-16-1
• Molecular Formula: C₁₄H₁₅NO
• Molecular Weight: 213.27
• Product Categories: chiral;Chiral reagent;Amino Alcohols (Chiral);Chiral Building Blocks;for Resolution of Acids;Optical Resolution;Synthetic Organic Chemistry;Amino Alcohols & Deriv.;CHIRAL CHEMICALS;Chiral Compound;Amino Alcohols;Chiral Building Blocks;Organic Building Blocks
• Mol File: 23190-16-1.mol
• Article Data: 56

Chemical Properties

• Melting Point: 142-144 °C(lit.)
• Boiling Point: 261 °C at 760 mmHg
• Flash Point: 125.3 °C
• Appearance: white to light-yellow/Powder
• Density: 1.148 g/cm₃
• Vapor Pressure: 2.88E-06mmHg at 25°C
• Refractive Index: -7 ° (C=0.6, EtOH)
• Storage Temp.: 2-8°C
• Solubility: Chloroform, Ethanol, Methanol
• PKA: 11.70±0.45(Predicted)
• BRN: 2806218
• CAS DataBase Reference: (1R,2S)-2-Amino-1,2-diphenylethanol(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,2S)-2-Amino-1,2-diphenylethanol(23190-16-1)
• EPA Substance Registry System: (1R,2S)-2-Amino-1,2-diphenylethanol(23190-16-1)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• F: 10
• Hazardous Substances Data: 23190-16-1(Hazardous Substances Data)

Usage

Chemical Properties

white to light yellow crystal powde

Uses

Different sources of media describe the Uses of 23190-16-1 differently. You can refer to the following data:
1. (1R,2S)-(-)-2-Amino-1,2-diphenylethanol is a hydroxylated 1,2-diphenethylamine derivative with affinity for the NMDA receptor.
2. Chiral auxiliary used for Pd(II)-assisted chiral tandem alkylation and carbonylative coupling reactions.

InChI:InChI=1/C14H15NO/c15-13(11-7-3-1-4-8-11)14(16)12-9-5-2-6-10-12/h1-10,13-14,16H,15H2/t13-,14+/m0/s1

Upstream product

• 64-17-5 ethanol 
• 87-69-4 L-Tartaric acid 
• 530-36-9 threo-1,2-diphenyl-2-aminoethan-1-ol 
• 572-45-2 benzil dioxime 
• 618-65-5 helicin 
• 70981-26-9 α'-benzylidenamino-bibenzyl-α-ol 
• 441-38-3 benzoin oxime 
• 574-15-2 benzilmonoxime 
• 1689-71-0 2,3-diphenyloxirane 
• 7677-24-9 trimethylsilyl cyanide 
• 100-52-7 benzaldehyde 
• 780-25-6 N-benzylidene benzylamine 
• 169899-58-5 2-(1-hydroxy-1-phenylmethyl)-4,5-dimethylthiazole 
• 5908-41-8 benzoyltrimethylsilane 

Downstream Products

• 6275-45-2 dichloro-acetic acid-(α'-hydroxy-bibenzyl-α-ylamide) 
• 530-36-9 (1R,2R)-2-amino-1,2-diphenylethane-1-ol 
• 492-70-6 1,2-diphenyl-1,2-ethanediol 
• 530-36-9 (1S,2S)-2-amino-1,2-diphenylethanol 
• 530-36-9 2-amino-1,2-diphenylethanol 
• 49855-40-5 L_g-threo-α'-chloro-bibenzyl-α-ylamine 
• 6287-74-7 (+/-)-erythro-α'-(2-diethylamino-ethylamino)-bibenzyl-α-ol 
• 23364-44-5 (1S,2R)-2-Amino-1,2-diphenylethanol 
• 530-36-9 threo-1,2-diphenyl-2-aminoethan-1-ol 
• 49855-40-5 (+/-)-erythro-α'-chloro-bibenzylyl-(α)-amine 
• 49855-40-5 (+/-)-threo-α'-chloro-bibenzylyl-(α)-amine 
• 780-25-6 N-benzylidene benzylamine 
• 100-52-7 benzaldehyde 
• 100-46-9 benzylamine 

Relevant articles and documents

Double Asymmetric Hydrogenation of α-Iminoketones: Facile Synthesis of Enantiopure Vicinal Amino Alcohols

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