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CAS

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2544-29-8

N2-acetylfolic acid, also known as 5,6,7,8-tetrahydrofolic acid, is a synthetic derivative of folic acid, a B-vitamin essential for various biological processes. It plays a crucial role in the synthesis of DNA, RNA, and proteins, as well as in the metabolism of homocysteine. N2-acetylfolic acid is often used as a dietary supplement to address folic acid deficiencies, which can lead to anemia, neural tube defects in developing fetuses, and other health issues. It is also used in the treatment of megaloblastic anemia and can be found in fortified foods and supplements. The chemical structure of N2-acetylfolic acid features an acetyl group attached to the nitrogen at position 2 of the pteridine ring, which is part of the folic acid molecule.

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  • 2544-29-8 Structure

  • Basic information

    1. Product Name: N(2)-acetylfolic acid
    2. Synonyms: N(2)-acetylfolic acid
    3. CAS NO:2544-29-8
    4. Molecular Formula:
    5. Molecular Weight: 483.44
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 2544-29-8.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: N(2)-acetylfolic acid(CAS DataBase Reference)
    10. NIST Chemistry Reference: N(2)-acetylfolic acid(2544-29-8)
    11. EPA Substance Registry System: N(2)-acetylfolic acid(2544-29-8)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 2544-29-8(Hazardous Substances Data)

2544-29-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 2544-29-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,5,4 and 4 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 2544-29:
(6*2)+(5*5)+(4*4)+(3*4)+(2*2)+(1*9)=78
78 % 10 = 8
So 2544-29-8 is a valid CAS Registry Number.

2544-29-8Downstream Products

2544-29-8Relevant articles and documents

The synthesis of folic acid, multiply labelled with stable isotopes, for bio-availability studies in human nutrition

Maunder, Peter,Finglas, Paul M.,Mallet, Anthony I.,Mellon, Fred A.,Aaqib Razzaque,Ridge, Brian,Vahteristo, Liisa,Witthoeft, Cornelia

, p. 1311 - 1323 (2007/10/03)

Two different methods for the synthesis of folic acid, which are suitable for the incorporation of compounds multiply labelled with stable isotopes, are described. The first method is based on the use of a novel reductive amination to link 2-acetyIamino-4-hydroxy-6-formylpteridine withp-aminobenzoyl-L-glutamic acid. The second method is based on the penultimate formation of an amide bond between Ar-2-acetyl-Ar-10-trifluoroacetyIpteroic acid and dimethyl L-glutamate. Both methods have been used to transform [13C6]aniline into folic acid, labelled with [13C6] in the p-aminobenzoate moiety, and [3,3,4,4-2H4]-L-glutamic acid into folic acid, labelled with [2H4] in the glutamate moiety. Doubly labelled [13C6,2H 4]-p-aminobenzoyl-L-glutamate has also been prepared by the former method.

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