31162-13-7

Basic information

• Product Name: 2-Azidobenzoic acid
• Synonyms: 2-Azidobenzoic acid;o-Azidobenzoic acid;2-Azidobenzoic acid solution;2-Azidobenzoic acid solution ~0.25 M in tert-butyl methyl ether, >=95.0% (HPLC)
• CAS NO: 31162-13-7
• Molecular Formula: C₇H₅N₃O₂
• Molecular Weight: 0
• Mol File: 31162-13-7.mol
• Article Data: 58

Chemical Properties

• Melting Point: 142-143 °C (decomp)
• Flash Point: -33℃
• Appearance: /
• Storage Temp.: ?20°C
• Solubility: Chloroform (Slightly, Sonicated), DMSO (Slightly)
• BRN: 1950619
• CAS DataBase Reference: 2-Azidobenzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Azidobenzoic acid(31162-13-7)
• EPA Substance Registry System: 2-Azidobenzoic acid(31162-13-7)

Safety Data

• Hazard Codes: F,Xi
• Statements: 11-38
• Safety Statements: 16
• RIDADR: UN 2398 3 / PGII
• WGK Germany: 3
• Hazardous Substances Data: 31162-13-7(Hazardous Substances Data)

Usage

Synthesis

The solution of the corresponding 2-aminobenzoic acid (15.3 mmol) in water (15 mL) and conc. HCl (17 mL) was placed in a 200 mL beaker and cooled to 5 °C. To this mixture a precooled solution of sodium nitrite (1.06 g, 15.3 mmol in 10 mL water) was added drop wise with vigorous stirring. After stirring for 15 min, a solution of sodium azide (1.08 g, 16.6 mmol) in 10 mL water was added and the resulting mixture was gradually warmed to room temperature and stirred at this temperature for about 2 h. The white crystalline azides precipitated from the reaction mixture and were filtered off. After washing with cold water and drying in the dark at room temperature the azides were recrystallized from heptane/benzene (v/v, 1:1).?1H NMR (400 MHz, CDCl3) δ 10.65 ?(s, 1H), 8.11 (dd, J = 7.9, 1.5 Hz, 1H), 7.66 – 7.56 (m, 1H), 7.31 – 7.21 (m, 2H). 13C ?NMR (101 MHz, CDCl3) δ 168.8, 140.4, 134.6, 133.4, 125.1, 120.9, 119.7.

Uses

2-Azidobenzoic Acid can be used for polyethylene surface with aryl azides.

Upstream product

• 1427465-36-8 1-(4-chlorophenyl)-1λ³-benzo[d][1,2]iodaoxol-3(1H)-one 
• 1427465-34-6 1-(2,4,6-trimethylphenyl)-1H-1λ³-benzo[b]iodo-3(2H)-one 
• 1427465-29-9 1-(4-methylphenyl)-1H-1λ³-benzo[b]iodo-3(2H)-one 
• 552-16-9 ortho-nitrobenzoic acid 
• 90701-81-8 2-azidobenzohydrazide 
• 34897-85-3 o-azidobenzoyl chloride 
• 41225-81-4 3-amino-1,2,3-benzotriazin-4(3H)-one 
• 88-67-5 2-Iodobenzoic acid 
• 90701-80-7 N-(o-azidobenzoyl)-p-chlorobenzaldehyd hydrazone 
• 118-92-3 anthranilic acid 
• 40515-78-4 (E)-3-(2-azidophenyl)acrylic acid 
• 90323-83-4 (4-oxo-4H-benzo[d][1,2,3]triazin-3-yl)-carbamic acid methyl ester 
• 75681-26-4 3-acetylamino-3H-benzo[d][1,2,3]triazin-4-one 
• 612-27-1 2-nitroso-benzoic acid 

Downstream Products

• 63254-88-6 2-{[(benzyloxy)carbonyl]amino}benzoic acid 
• 623583-11-9 (2-Azido-phenyl)-((2S,4S)-4-fluoro-2-hydroxymethyl-pyrrolidin-1-yl)-methanone 
• 623583-12-0 (2-Azido-phenyl)-((2S,4R)-4-fluoro-2-hydroxymethyl-pyrrolidin-1-yl)-methanone 
• 623583-13-1 (2-Azido-phenyl)-((S)-4,4-difluoro-2-hydroxymethyl-pyrrolidin-1-yl)-methanone 
• 196928-08-2 (3S)-[1-(2-azidobenzoyl)]-3,4-dihydro-4-methyl-3-phenylmethyl-[1,4]benzodiazepin-2,5(1H)-dione 
• 196928-07-1 N-(2-azidobenzoyl)-N-methyl-L-phenylalanine methyl ester 
• 211567-41-8 (3S)-3,4-dihydro-2-methoxy-N-methyl-3-phenylmethyl-[1,4]benzodiazepin-5(5H)one 
• 50886-63-0 (3S)-3,4-dihydro-4-methyl-3-phenylmethyl-[1,4]benzodiazepin-2,5(1H)-dione 
• 1025937-27-2 2-(3-chloro-phenyliminomethyleneamino)-benzoic acid ethyl ester 
• 622403-42-3 1-phenyl-3-(2-ethoxycarbonylphenyl) carbodiimide 
• 179039-70-4 ethyl 2-(triphenylphosphoranylidene-amino)benzoate 
• 622403-43-4 2-(4-Chloro-phenyliminomethyleneamino)-benzoic acid ethyl ester 
• 741-75-3 2-(piperidin-1-yl)-3-phenylquinazolin-4(3H)-one 

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